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Biology and Biochemistry

D-Index
124
Citations
50493
World Ranking
534
National Ranking
336

Overview

Victor M. Darley-Usmar is affiliated with the University of Alabama at Birmingham in the United States. Their research primarily spans the fields of Biochemistry, Genetics and Molecular Biology, and Medicine, with a strong focus on Molecular Biology, Physiology, and Immunology as major subfields. Their work also extends into Cancer Research and Cardiology and Cardiovascular Medicine.

Their research topics include:

  • Mitochondrial Function and Pathology
  • Glycosylation and Glycoproteins Research
  • Cancer, Hypoxia, and Metabolism
  • Epigenetics and DNA Methylation
  • Autophagy in Disease and Therapy
  • Carbohydrate Chemistry and Synthesis
  • Metabolism and Genetic Disorders

Victor M. Darley-Usmar has contributed to several recent scientific papers, covering various aspects of cellular metabolism, immune regulation, and disease mechanisms. Selected publications include:

  • "A novel approach to measure mitochondrial respiration in frozen biological samples" (2020), The EMBO Journal
  • "Lung Tumor Cell-Derived Exosomes Promote M2 Macrophage Polarization" (2020), Cells
  • "Insulin-Like Growth Factors Are Key Regulators of T Helper 17 Regulatory T Cell Balance in Autoimmunity" (2020), Immunity
  • "Fasting drives the metabolic, molecular and geroprotective effects of a calorie-restricted diet in mice" (2021), Nature Metabolism
  • "Mitochondrial Oxidative Phosphorylation Regulates the Fate Decision between Pathogenic Th17 and Regulatory T Cells" (2020), Cell Reports

The scientist frequently collaborates with other researchers including Gloria A. Benavides, Jianhua Zhang, Xiaosen Ouyang, Michelle S. Johnson, and Martin E. Young. These partnerships have contributed to a sustained body of work across multiple studies and publications.

Victor M. Darley-Usmar's publications are commonly found in the following venues:

  • Free Radical Biology and Medicine
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Cancer Research
  • Frontiers in Aging
  • Acta Pharmaceutica Sinica B

Best Publications

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • Measuring reactive oxygen and nitrogen species with fluorescent probes: challenges and limitations.

    Balaraman Kalyanaraman;Victor Darley-Usmar;Kelvin J.A. Davies;Phyllis A. Dennery

  • Reversible inhibition of cytochrome c oxidase, the terminal enzyme of the mitochondrial respiratory chain, by nitric oxide. Implications for neurodegenerative diseases.

    M.W.J. Cleeter;J.M. Cooper;V.M. Darley-Usmar;S. Moncada

  • Hydrogen sulfide mediates the vasoactivity of garlic

    Gloria A. Benavides;Giuseppe L. Squadrito;Robert W. Mills;Hetal D. Patel

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • Production of hydroxyl radicals from the simultaneous generation of superoxide and nitric oxide.

    N Hogg;V M Darley-Usmar;M T Wilson;S Moncada

  • Nitric oxide and oxygen radicals: a question of balance

    Victor Darley-Usmar;Helen Wiseman;Barry Halliwell

  • Oxidative Stress Induces Vascular Calcification Through Modulation of the Osteogenic Transcription Factor Runx2 by AKT Signaling

    Chang Hyun Byon;Amjad Javed;Qun Dai;John C. Kappes

  • Cellular mechanisms of redox cell signalling: role of cysteine modification in controlling antioxidant defences in response to electrophilic lipid oxidation products.

    Anna-Liisa Levonen;Aimee Landar;Anup Ramachandran;Erin K. Ceaser

  • Biological aspects of reactive nitrogen species.

    Rakesh P. Patel;Joanne McAndrew;Hassan Sellak;C.Roger White

  • Deoxymyoglobin is a Nitrite Reductase That Generates Nitric Oxide and Regulates Mitochondrial Respiration

    Sruti Shiva;Zhi Huang;Rozalina Grubina;Junhui Sun

  • The Simultaneous Generation of Superoxide and Nitric Oxide Can Initiate Lipid Peroxidation in Human Low Density Lipoprotein

    Victor M. Darley-usmar;Neil Hogg;Vanessa J. O'leary;Michael T. Wilson

  • Hypoxia, red blood cells, and nitrite regulate NO-dependent hypoxic vasodilation

    Jack H. Crawford;T. Scott Isbell;T. Scott Isbell;T. Scott Isbell;Zhi Huang;Zhi Huang;Zhi Huang;Sruti Shiva;Sruti Shiva;Sruti Shiva

  • cGMP mediates the vascular and platelet actions of nitric oxide: confirmation using an inhibitor of the soluble guanylyl cyclase

    Maria A. Moro;Rachel J. Russell;Selim Cellek;Ignacio Lizasoain

  • Integration of cellular bioenergetics with mitochondrial quality control and autophagy.

    Bradford G Hill;Gloria A Benavides;Jack R Lancaster;Scott Ballinger

  • Blood radicals: reactive nitrogen species, reactive oxygen species, transition metal ions, and the vascular system.

    Victor Darley-Usmar;Barry Halliwell

  • Assessing bioenergetic function in response to oxidative stress by metabolic profiling

    Brian P. Dranka;Gloria A. Benavides;Anne R. Diers;Samantha Giordano

  • Circulating plasma xanthine oxidase contributes to vascular dysfunction in hypercholesterolemic rabbits

    C R White;V Darley-Usmar;W R Berrington;M McAdams

  • Paradoxical fate and biological action of peroxynitrite on human platelets

    María Ángeles Moro;Victor M. Darley-Usmar;David A. Goodwin;Nicholas G. Read

  • Metformin reverses established lung fibrosis in a bleomycin model.

    Sunad Rangarajan;Nathaniel B. Bone;Anna A. Zmijewska;Shaoning Jiang

Frequent Co-Authors

Jianhua Zhang
Jianhua Zhang The University of Texas MD Anderson Cancer Center
Stephen Barnes
Stephen Barnes University of Alabama at Birmingham
Paul S. Brookes
Paul S. Brookes University of Rochester Medical Center
Anna-Liisa Levonen
Anna-Liisa Levonen University of Eastern Finland
Marion Kirk
Marion Kirk University of Alabama at Birmingham
Neil Hogg
Neil Hogg Medical College of Wisconsin
Jaroslaw W. Zmijewski
Jaroslaw W. Zmijewski University of Alabama at Birmingham
Anita B. Hjelmeland
Anita B. Hjelmeland University of Alabama at Birmingham
Bruce A. Freeman
Bruce A. Freeman University of Pittsburgh
Hanjoong Jo
Hanjoong Jo Emory University

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