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Biology and Biochemistry

D-Index
52
Citations
23227
World Ranking
16428
National Ranking
6793

Overview

Anita B. Hjelmeland is affiliated with the University of Alabama at Birmingham in the United States. Their research spans multiple areas within biochemistry, genetics, molecular biology, and medicine, with significant focus on oncology and cancer research.

Their scholarly output includes 52 publications in both the fields of Biochemistry, Genetics and Molecular Biology, and Medicine. Their subfields of study further specify Molecular Biology (24 publications), Oncology (18 publications), Cancer Research (17 publications), Genetics (16 publications), and Immunology (11 publications).

Major topics addressed in their work involve:

  • Glioma Diagnosis and Treatment
  • Cancer, Hypoxia, and Metabolism
  • Cancer Cells and Metastasis
  • Cancer Genomics and Diagnostics
  • Mitochondrial Function and Pathology
  • Cancer Research and Treatments
  • CAR-T cell therapy research

Hjelmeland's recent papers include:

  • "Glioma stem cells and their roles within the hypoxic tumor microenvironment," 2020, published in Theranostics
  • "GAP43-dependent mitochondria transfer from astrocytes enhances glioblastoma tumorigenicity," 2023, published in Nature Cancer
  • "Reactive oxygen species produced by altered tumor metabolism impacts cancer stem cell maintenance," 2021, published in Redox Biology
  • "Sphingolipid Metabolism in Glioblastoma and Metastatic Brain Tumors: A Review of Sphingomyelinases and Sphingosine-1-Phosphate," 2020, published in Biomolecules
  • "Regulation of NKG2D Stress Ligands and Its Relevance in Cancer Progression," 2022, published in Cancers

Frequent collaborators in their research include Amber B. Jones, Christopher D. Willey, Joshua C. Anderson, Kaysaw Tuy, and Sarah Williford.

Key journals and venues where Hjelmeland has published frequently consist of Neuro-Oncology (10 publications), bioRxiv (Cold Spring Harbor Laboratory) (5 publications), Cells (3 publications), Cancers (2 publications), and JCI Insight (2 publications).

Best Publications

  • Glioma stem cells promote radioresistance by preferential activation of the DNA damage response

    Shideng Bao;Qiulian Wu;Roger E McLendon;Yueling Hao

  • Stem cell-like glioma cells promote tumor angiogenesis through vascular endothelial growth factor

    Shideng Bao;Qiulian Wu;Sith Sathornsumetee;Yueling Hao

  • Hypoxia-Inducible Factors Regulate Tumorigenic Capacity of Glioma Stem Cells

    Zhizhong Li;Shideng Bao;Shideng Bao;Qiulian Wu;Qiulian Wu;Hui Wang

  • The Hypoxic Microenvironment Maintains Glioblastoma Stem Cells and Promotes Reprogramming towards a Cancer Stem Cell Phenotype

    John M. Heddleston;Zhizhong Li;Roger E. McLendon;Anita B. Hjelmeland

  • Integrin Alpha 6 regulates glioblastoma stem cells

    Justin D. Lathia;Joseph Gallagher;John M. Heddleston;Jialiang Wang

  • Notch promotes radioresistance of glioma stem cells

    Jialiang Wang;Timothy P. Wakeman;Justin D. Lathia;Anita B. Hjelmeland

  • Hypoxia inducible factors in cancer stem cells

    J. M. Heddleston;Zong-Ming Li;Justin D Lathia;Shideng Bao

  • Targeting cancer stem cells through L1CAM suppresses glioma growth.

    Shideng Bao;Qiulian Wu;Zhizhong Li;Sith Sathornsumetee

  • Brain tumor initiating cells adapt to restricted nutrition through preferential glucose uptake

    William A Flavahan;Qiulian Wu;Masahiro Hitomi;Nasiha Rahim

  • c-Myc is required for maintenance of glioma cancer stem cells.

    Jialiang Wang;Hui Wang;Zhizhong Li;Qiulian Wu

  • Acidic stress promotes a glioma stem cell phenotype

    A. B. Hjelmeland;Q. Wu;J. M. Heddleston;G. S. Choudhary

  • Targeting Interleukin 6 Signaling Suppresses Glioma Stem Cell Survival and Tumor Growth

    Hui Wang;Justin D. Lathia;Qiulian Wu;Jialiang Wang

  • Chemotherapy activates cancer-associated fibroblasts to maintain colorectal cancer-initiating cells by IL-17A

    Fiorenza Lotti;Awad M. Jarrar;Rish K. Pai;Masahiro Hitomi;Masahiro Hitomi

  • Glioma Stem Cell Proliferation and Tumor Growth Are Promoted by Nitric Oxide Synthase-2

    Christine E. Eyler;Qiulian Wu;Kenneth Yan;Jennifer M. MacSwords

  • Brain Cancer Stem Cells Display Preferential Sensitivity to Akt Inhibition

    Christine E. Eyler;Wen Chi Foo;Katherine M. LaFiura;Roger E. McLendon

  • Nonreceptor Tyrosine Kinase BMX Maintains Self-Renewal and Tumorigenic Potential of Glioblastoma Stem Cells by Activating STAT3

    Olga A. Guryanova;Qiulian Wu;Lin Cheng;Lin Cheng;Justin D Lathia

  • SB-431542, a small molecule transforming growth factor-β-receptor antagonist, inhibits human glioma cell line proliferation and motility

    Mark D. Hjelmeland;Anita B. Hjelmeland;Sith Sathornsumetee;Elizabeth D. Reese

  • A novel low‐molecular weight inhibitor of focal adhesion kinase, TAE226, inhibits glioma growth

    Qing Shi;Anita B. Hjelmeland;Stephen T. Keir;Linhua Song

  • Distribution of CD133 reveals glioma stem cells self-renew through symmetric and asymmetric cell divisions.

    J D Lathia;M Hitomi;J Gallagher;S P Gadani

  • Targeting SPARC expression decreases glioma cellular survival and invasion associated with reduced activities of FAK and ILK kinases.

    Q Shi;S Bao;L Song;Q Wu

Frequent Co-Authors

Jeremy N. Rich
Jeremy N. Rich University of Pittsburgh
Justin D. Lathia
Justin D. Lathia Cleveland Clinic Lerner College of Medicine
Roger E. McLendon
Roger E. McLendon Duke University
Victor M. Darley-Usmar
Victor M. Darley-Usmar University of Alabama at Birmingham
G. Yancey Gillespie
G. Yancey Gillespie University of Alabama at Birmingham
Shideng Bao
Shideng Bao Cleveland Clinic Lerner College of Medicine
Darell D. Bigner
Darell D. Bigner Duke University
Xiao-Fan Wang
Xiao-Fan Wang Duke University
Jianhua Zhang
Jianhua Zhang The University of Texas MD Anderson Cancer Center
Hui Wang
Hui Wang University of Ulster

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