His scientific interests lie mostly in Cancer research, Stem cell, Neural stem cell, Cancer stem cell and Neurosphere. His research integrates issues of Radioresistance, Mesenchymal stem cell and Phosphorylation in his study of Cancer research. His Stem cell research incorporates themes from Gene knockdown, Immunology, Pathology, Signal transduction and Maternal embryonic leucine zipper kinase.
His study looks at the relationship between Neural stem cell and fields such as Adult stem cell, as well as how they intersect with chemical problems. As part of one scientific family, Ichiro Nakano deals mainly with the area of Neurosphere, narrowing it down to issues related to the Cell biology, and often Glial fibrillary acidic protein, Splicing factor, RNA splicing and Cell. His studies deal with areas such as SOX2 and Amniotic stem cells as well as Neuroepithelial cell.
Cancer research, Stem cell, Glioma, Cancer stem cell and Cell biology are his primary areas of study. The concepts of his Cancer research study are interwoven with issues in Carcinogenesis, Cancer, Immunology, Signal transduction and Mesenchymal stem cell. His work focuses on many connections between Stem cell and other disciplines, such as Neurosphere, that overlap with his field of interest in CD44.
His research in Glioma intersects with topics in Phenotype, Radioresistance and Cell. The study incorporates disciplines such as PI3K/AKT/mTOR pathway and Bioinformatics in addition to Cancer stem cell. In his research on the topic of Cell biology, Gene knockdown is strongly related with Molecular biology.
His primary scientific interests are in Cancer research, Glioma, Glioblastoma, Stem cell and Cell biology. His Cancer research study combines topics from a wide range of disciplines, such as Cancer, Cell, Phenotype, Signal transduction and Mesenchymal stem cell. His Glioma study combines topics in areas such as Angiogenesis, Cell growth, Tumor microenvironment, Cancer stem cell and NF-κB.
Ichiro Nakano combines subjects such as Clinical trial and Tumor cells with his study of Glioblastoma. His work carried out in the field of Stem cell brings together such families of science as Cell culture, Ectopic expression, Apoptosis, Neurosphere and Temozolomide. His Cell biology study integrates concerns from other disciplines, such as RNA splicing, Beta oxidation, RNA-binding protein and Alternative splicing.
Ichiro Nakano spends much of his time researching Cancer research, Glioma, Mesenchymal stem cell, Stem cell and Signal transduction. His Cancer research research is multidisciplinary, incorporating elements of Immune checkpoint, Cancer, Apoptosis and Regulation of gene expression, Gene. His studies in Glioma integrate themes in fields like Transcriptome, Gene expression, Transition, Phenotype and Radioresistance.
His Mesenchymal stem cell study combines topics in areas such as PD-L1, T-cell receptor, Tumor progression, Gene silencing and Programmed cell death. The Stem cell study combines topics in areas such as Autophagy and Cell growth. In his study, which falls under the umbrella issue of Signal transduction, Cell biology, RHOA and Biochemistry is strongly linked to Cancer cell.
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Cancerous stem cells can arise from pediatric brain tumors
Houman D. Hemmati;Ichiro Nakano;Jorge A. Lazareff;Michael Masterman-Smith.
Proceedings of the National Academy of Sciences of the United States of America (2003)
Mesenchymal Differentiation Mediated by NF-κB Promotes Radiation Resistance in Glioblastoma
Krishna P.L. Bhat;Veerakumar Balasubramaniyan;Brian Vaillant;Ravesanker Ezhilarasan.
Cancer Cell (2013)
Phosphorylation of EZH2 activates STAT3 signaling via STAT3 methylation and promotes tumorigenicity of glioblastoma stem-like cells
Eunhee Kim;Misuk Kim;Dong Hun Woo;Yongjae Shin.
Cancer Cell (2013)
Mesenchymal glioma stem cells are maintained by activated glycolytic metabolism involving aldehyde dehydrogenase 1A3.
Ping Mao;Kaushal Joshi;Jianfeng Li;Sung Hak Kim.
Proceedings of the National Academy of Sciences of the United States of America (2013)
Brain tumor initiating cells adapt to restricted nutrition through preferential glucose uptake
William A Flavahan;Qiulian Wu;Masahiro Hitomi;Nasiha Rahim.
Nature Neuroscience (2013)
Immune evasion mediated by PD-L1 on glioblastoma-derived extracellular vesicles
Franz L. Ricklefs;Franz L. Ricklefs;Quazim Alayo;Harald Krenzlin;Ahmad B. Mahmoud;Ahmad B. Mahmoud.
Science Advances (2018)
Incorporation and differentiation of hippocampus-derived neural stem cells transplanted in injured adult rat retina.
Akihiro Nishida;Masayo Takahashi;Hidenobu Tanihara;Ichiro Nakano.
Investigative Ophthalmology & Visual Science (2000)
MiR-21 in the extracellular vesicles (EVs) of cerebrospinal fluid (CSF): a platform for glioblastoma biomarker development.
Johnny C. Akers;Valya Ramakrishnan;Ryan Kim;Johan Skog.
PLOS ONE (2013)
CAR-Engineered NK Cells Targeting Wild-Type EGFR and EGFRvIII Enhance Killing of Glioblastoma and Patient-Derived Glioblastoma Stem Cells.
Jianfeng Han;Jianhong Chu;Wing Keung Chan;Jianying Zhang.
Scientific Reports (2015)
Extracellular Vesicles Modulate the Glioblastoma Microenvironment via a Tumor Suppression Signaling Network Directed by miR-1
Agnieszka Bronisz;Agnieszka Bronisz;Yan Wang;Michal O. Nowicki;Michal O. Nowicki;Pierpaolo Peruzzi.
Cancer Research (2014)
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