World's Best Scientists 2026 revealed!

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Biology and Biochemistry

D-Index
73
Citations
19636
World Ranking
5917
National Ranking
2799

Overview

Ichiro Nakano is a researcher affiliated with the University of Alabama at Birmingham in the United States. Their work is situated primarily within the fields of biochemistry, genetics, molecular biology, and medicine, with a focus on cancer research, immunology, and neurology.

The scientist's research explores key topics including:

  • Glioma diagnosis and treatment
  • Extracellular vesicles in disease
  • Cancer, hypoxia, and metabolism
  • MicroRNA in disease regulation
  • Epigenetics and DNA methylation
  • Neuroblastoma research and treatments
  • Circular RNAs in diseases

Several recent publications by Nakano illustrate a focus on glioblastoma and glioma biology. Notable papers include:

  • "Glioma-initiating cells at tumor edge gain signals from tumor core cells to promote their malignancy" (2020, Nature Communications)
  • "Enhanced fatty acid oxidation provides glioblastoma cells metabolic plasticity to accommodate to its dynamic nutrient microenvironment" (2020, Cell Death and Disease)
  • "PRMT6 methylation of RCC1 regulates mitosis, tumorigenicity, and radiation response of glioblastoma stem cells" (2021, Molecular Cell)
  • "An Update on Neurofibromatosis Type 1-Associated Gliomas" (2020, Cancers)
  • "Imidazo[1,2-a]pyridine Derivatives as Aldehyde Dehydrogenase Inhibitors: Novel Chemotypes to Target Glioblastoma Stem Cells" (2020, Journal of Medicinal Chemistry)

Nakano has collaborated frequently with several researchers, including:

  • Harley I. Kornblum
  • Soniya Bastola
  • Daisuke Yamashita
  • Bakhos A. Tannous
  • Riki Kawaguchi

The scientist's work is often published in specific venues associated with oncology and molecular biology. Frequent publication venues include:

  • Neuro-Oncology
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Communications
  • Journal of Clinical Investigation
  • Neuro-Oncology Advances

The subfields of study most represented in Nakano's publications are molecular biology, genetics, cancer research, immunology, and neurology. These areas underscore a focus on the cellular and molecular mechanisms underlying cancer and neurological disorders.

Best Publications

  • Cancerous stem cells can arise from pediatric brain tumors

    Houman D. Hemmati;Ichiro Nakano;Jorge A. Lazareff;Michael Masterman-Smith

  • Mesenchymal Differentiation Mediated by NF-κB Promotes Radiation Resistance in Glioblastoma

    Krishna P.L. Bhat;Veerakumar Balasubramaniyan;Brian Vaillant;Ravesanker Ezhilarasan

  • Phosphorylation of EZH2 activates STAT3 signaling via STAT3 methylation and promotes tumorigenicity of glioblastoma stem-like cells

    Eunhee Kim;Misuk Kim;Dong Hun Woo;Yongjae Shin

  • Mesenchymal glioma stem cells are maintained by activated glycolytic metabolism involving aldehyde dehydrogenase 1A3.

    Ping Mao;Kaushal Joshi;Jianfeng Li;Sung Hak Kim

  • Immune evasion mediated by PD-L1 on glioblastoma-derived extracellular vesicles

    Franz L. Ricklefs;Franz L. Ricklefs;Quazim Alayo;Harald Krenzlin;Ahmad B. Mahmoud;Ahmad B. Mahmoud

  • Brain tumor initiating cells adapt to restricted nutrition through preferential glucose uptake

    William A Flavahan;Qiulian Wu;Masahiro Hitomi;Nasiha Rahim

  • CAR-Engineered NK Cells Targeting Wild-Type EGFR and EGFRvIII Enhance Killing of Glioblastoma and Patient-Derived Glioblastoma Stem Cells.

    Jianfeng Han;Jianhong Chu;Wing Keung Chan;Jianying Zhang

  • MiR-21 in the extracellular vesicles (EVs) of cerebrospinal fluid (CSF): a platform for glioblastoma biomarker development.

    Johnny C. Akers;Valya Ramakrishnan;Ryan Kim;Johan Skog

  • Incorporation and differentiation of hippocampus-derived neural stem cells transplanted in injured adult rat retina.

    Akihiro Nishida;Masayo Takahashi;Hidenobu Tanihara;Ichiro Nakano

  • Apoptotic Cell-Derived Extracellular Vesicles Promote Malignancy of Glioblastoma Via Intercellular Transfer of Splicing Factors.

    Marat S. Pavlyukov;Hai Yu;Hai Yu;Soniya Bastola;Mutsuko Minata

  • The AMPK Inhibitor Compound C Is a Potent AMPK-Independent Antiglioma Agent

    Xiaona Liu;Rishi Raj Chhipa;Ichiro Nakano;Biplab Dasgupta

  • Inhibition of SOAT1 suppresses glioblastoma growth via blocking SREBP-1-mediated lipogenesis

    Feng Geng;Xiang Cheng;Xiaoning Wu;Ji Young Yoo

  • Cancer Stem Cell-Secreted Macrophage Migration Inhibitory Factor Stimulates Myeloid Derived Suppressor Cell Function and Facilitates Glioblastoma Immune Evasion

    Balint Otvos;Daniel J Silver;Erin E Mulkearns-Hubert;Alvaro G Alvarado

  • Extracellular Vesicles Modulate the Glioblastoma Microenvironment via a Tumor Suppression Signaling Network Directed by miR-1

    Agnieszka Bronisz;Agnieszka Bronisz;Yan Wang;Michal O. Nowicki;Michal O. Nowicki;Pierpaolo Peruzzi

  • MELK-dependent FOXM1 phosphorylation is essential for proliferation of glioma stem cells.

    Kaushal Joshi;Yeshavanth Banasavadi-Siddegowda;Xiaokui Mo;Sung-Hak Kim

  • MST4 Phosphorylation of ATG4B Regulates Autophagic Activity, Tumorigenicity, and Radioresistance in Glioblastoma

    Tianzhi Huang;Chung Kwon Kim;Chung Kwon Kim;Angel A. Alvarez;Rajendra P. Pangeni;Rajendra P. Pangeni

  • Phenotypic Plasticity of Invasive Edge Glioma Stem-like Cells in Response to Ionizing Radiation

    Mutsuko Minata;Alessandra Audia;Junfeng Shi;Songjian Lu

  • The Long Non-coding RNA HIF1A-AS2 Facilitates the Maintenance of Mesenchymal Glioblastoma Stem-like Cells in Hypoxic Niches

    Marco Mineo;Franz Ricklefs;Franz Ricklefs;Arun K. Rooj;Shawn M. Lyons

  • EZH2 protects glioma stem cells from radiation-induced cell death in a MELK/FOXM1-dependent manner.

    Sung Hak Kim;Kaushal Joshi;Ravesanker Ezhilarasan;Toshia R. Myers

  • Laminin alpha 2 enables glioblastoma stem cell growth.

    Justin D. Lathia;Justin D. Lathia;Meizhang Li;Peter E. Hall;Joseph Gallagher

Frequent Co-Authors

Shi Yuan Cheng
Shi Yuan Cheng Northwestern University
E. Antonio Chiocca
E. Antonio Chiocca Brigham and Women's Hospital
Craig Horbinski
Craig Horbinski Northwestern University
Do-Hyun Nam
Do-Hyun Nam Samsung Medical Center
Jeremy N. Rich
Jeremy N. Rich University of Pittsburgh
Justin D. Lathia
Justin D. Lathia Cleveland Clinic Lerner College of Medicine
Bakhos A. Tannous
Bakhos A. Tannous Harvard University
Balveen Kaur
Balveen Kaur Augusta University
Jeongwu Lee
Jeongwu Lee Case Western Reserve University
Anita B. Hjelmeland
Anita B. Hjelmeland University of Alabama at Birmingham

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