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Biology and Biochemistry

D-Index
61
Citations
28757
World Ranking
11090
National Ranking
4795

Overview

Shideng Bao is affiliated with the Cleveland Clinic Lerner College of Medicine in the United States. Their research primarily spans the fields of Biochemistry, Genetics and Molecular Biology, with further contributions to Medicine. Within these fields, they have specialized in subfields including Molecular Biology, Cancer Research, Immunology, Oncology, and Epidemiology.

Their scientific work addresses several key topics, including:

  • RNA modifications and cancer
  • RNA research and splicing
  • Epigenetics and DNA methylation
  • Cancer-related molecular mechanisms research
  • Cancer, hypoxia, and metabolism
  • Autophagy in disease and therapy
  • Ubiquitin and proteasome pathways

Shideng Bao has published extensively in multiple high-impact journals. Frequent publication venues include:

  • Neuro-Oncology
  • Nature Communications
  • Science Translational Medicine
  • The Journal of Experimental Medicine
  • Neuro-Oncology Advances

Among recent publications authored or coauthored by Bao are:

  • "Inflammation mobilizes copper metabolism to promote colon tumorigenesis via an IL-17-STEAP4-XIAP axis," 2020, Nature Communications
  • "Dual Role of WISP1 in maintaining glioma stem cells and tumor-supportive macrophages in glioblastoma," 2020, Nature Communications
  • "Pharmacological inhibition of BACE1 suppresses glioblastoma growth by stimulating macrophage phagocytosis of tumor cells," 2021, Nature Cancer
  • "Inhibiting DNA-PK induces glioma stem cell differentiation and sensitizes glioblastoma to radiation in mice," 2021, Science Translational Medicine
  • "CD44+ lung cancer stem cell-derived pericyte-like cells cause brain metastases through GPR124-enhanced trans-endothelial migration," 2023, Cancer Cell

Collaborative efforts have involved frequent coauthors such as Jennifer S. Yu, Jeremy N. Rich, Kui Zhai, Zhi Huang, and Qiulian Wu, with each having contributed to multiple joint publications with Bao.

Best Publications

  • Glioma stem cells promote radioresistance by preferential activation of the DNA damage response

    Shideng Bao;Qiulian Wu;Roger E McLendon;Yueling Hao

  • Stem cell-like glioma cells promote tumor angiogenesis through vascular endothelial growth factor

    Shideng Bao;Qiulian Wu;Sith Sathornsumetee;Yueling Hao

  • Hypoxia-Inducible Factors Regulate Tumorigenic Capacity of Glioma Stem Cells

    Zhizhong Li;Shideng Bao;Shideng Bao;Qiulian Wu;Qiulian Wu;Hui Wang

  • Periostin secreted by glioblastoma stem cells recruits M2 tumour-associated macrophages and promotes malignant growth

    Wenchao Zhou;Susan Q. Ke;Zhi Huang;William Flavahan

  • Glioblastoma Stem Cells Generate Vascular Pericytes to Support Vessel Function and Tumor Growth

    Lin Cheng;Zhi Huang;Wenchao Zhou;Qiulian Wu

  • Cardiac defects and altered ryanodine receptor function in mice lacking FKBP12

    Weinian Shou;Bahman Aghdasi;Dawna L. Armstrong;Qiuxia Guo

  • Hypoxia inducible factors in cancer stem cells

    J. M. Heddleston;Zong-Ming Li;Justin D Lathia;Shideng Bao

  • BMP10 is essential for maintaining cardiac growth during murine cardiogenesis.

    Hanying Chen;Shu Shi;Lourdes Acosta;Weiming Li

  • Targeting cancer stem cells through L1CAM suppresses glioma growth.

    Shideng Bao;Qiulian Wu;Zhizhong Li;Sith Sathornsumetee

  • Cancer Stem Cells: The Architects of the Tumor Ecosystem.

    Briana C. Prager;Qi Xie;Shideng Bao;Jeremy N. Rich

  • Acquired Expression of Periostin by Human Breast Cancers Promotes Tumor Angiogenesis through Up-Regulation of Vascular Endothelial Growth Factor Receptor 2 Expression

    Rong Shao;Shideng Bao;Xuefang Bai;Carrie Blanchette

  • Mitochondrial control by DRP1 in brain tumor initiating cells

    Qi Xie;Qiulian Wu;Craig M Horbinski;William A Flavahan

  • ATR/ATM-mediated phosphorylation of human Rad17 is required for genotoxic stress responses.

    Shideng Bao;Randal S. Tibbetts;Kathryn M. Brumbaugh;Yanan Fang

  • Targeting glioma stem cells through combined BMI1 and EZH2 inhibition.

    Xun Jin;Xun Jin;Xun Jin;Leo J.Y. Kim;Qiulian Wu;Qiulian Wu;Lisa C. Wallace

  • Cancer stem cells in glioblastoma—molecular signaling and therapeutic targeting

    Zhi Huang;Lin Cheng;Olga A. Guryanova;Qiulian Wu

  • Nonreceptor Tyrosine Kinase BMX Maintains Self-Renewal and Tumorigenic Potential of Glioblastoma Stem Cells by Activating STAT3

    Olga A. Guryanova;Qiulian Wu;Lin Cheng;Lin Cheng;Justin D Lathia

  • Tumour-associated macrophages secrete pleiotrophin to promote PTPRZ1 signalling in glioblastoma stem cells for tumour growth

    Yu Shi;Yi Fang Ping;Yi Fang Ping;Wenchao Zhou;Zhi Cheng He;Zhi Cheng He

  • N6-methyladenine DNA Modification in Glioblastoma

    Qi Xie;Tao P. Wu;Ryan C. Gimple;Ryan C. Gimple;Zheng Li

  • Potential therapeutic implications of cancer stem cells in glioblastoma

    Lin Cheng;Shideng Bao;Jeremy N. Rich

  • EXTH-37. TARGETING GLIOMA STEM CELLS THROUGH COMBINED BMI1 AND EZH2 INHIBITION

    Xun Jin;Leo Kim;Qiulian Wu;Lisa C Wallace

Frequent Co-Authors

Jeremy N. Rich
Jeremy N. Rich University of Pittsburgh
Justin D. Lathia
Justin D. Lathia Cleveland Clinic Lerner College of Medicine
Anita B. Hjelmeland
Anita B. Hjelmeland University of Alabama at Birmingham
Roger E. McLendon
Roger E. McLendon Duke University
Xiu-Wu Bian
Xiu-Wu Bian Third Military Medical University
Xiaoxia Li
Xiaoxia Li Cleveland Clinic Lerner College of Medicine
Michael Weller
Michael Weller University of Zurich
Alexandru Almasan
Alexandru Almasan Cleveland Clinic Lerner College of Medicine
Tatiana V. Byzova
Tatiana V. Byzova Cleveland Clinic Lerner College of Medicine
Yong Li
Yong Li Baylor College of Medicine

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