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Toshifumi Aoyama

Toshifumi Aoyama

D-Index & Metrics

Biology and Biochemistry

D-Index
66
Citations
16762
World Ranking
8609
National Ranking
579

Overview

Toshifumi Aoyama is affiliated with Shinshu University in Japan. Their research primarily focuses on medicine and biochemistry, genetics, and molecular biology, contributing to a total of seven publications in medicine and five in biochemistry and related fields.

Aoyama's work encompasses several subfields, including epidemiology, molecular biology, endocrinology, diabetes and metabolism, cancer research, and hepatology. Specific research topics include liver disease diagnosis and treatment, diet, metabolism, and disease, regulation of FOXO transcription factors, cancer related to lipids and metabolism, peroxisome proliferator-activated receptors, hepatitis C virus research, and lysosomal storage disorders.

Their recent publications, spanning from 2020 to 2021, include the following:

  • Dietary Restriction Suppresses Steatosis-Associated Hepatic Tumorigenesis in Hepatitis C Virus Core Gene Transgenic Mice, 2020, Liver Cancer
  • A Saturated Fatty Acid-Rich Diet Enhances Hepatic Lipogenesis and Tumorigenesis in HCV Core Gene Transgenic Mice, 2020, The Journal of Nutritional Biochemistry
  • Polyunsaturated Fatty Acid Deficiency Affects Sulfatides and Other Sulfated Glycans in Lysosomes Through Autophagy-Mediated Degradation, 2020, The FASEB Journal
  • Mechanisms of Steatosis-Derived Hepatocarcinogenesis: Lessons from HCV Core Gene Transgenic Mice, 2021, Engineering

Frequent co-authors collaborating with Aoyama include Pan Diao, Naoki Tanaka, Fangping Jia, Xiaojing Wang, and Xiao Hu.

Key publication venues where Aoyama's work appears are Liver Cancer, The Journal of Nutritional Biochemistry, Engineering, and The FASEB Journal.

Best Publications

  • Diet-induced insulin resistance in mice lacking adiponectin/ACRP30.

    Norikazu Maeda;Iichiro Shimomura;Ken Kishida;Hitoshi Nishizawa

  • Altered Constitutive Expression of Fatty Acid-metabolizing Enzymes in Mice Lacking the Peroxisome Proliferator-activated Receptor α (PPARα)

    Toshifumi Aoyama;Jeffrey M. Peters;Nobuko Iritani;Tamie Nakajima

  • Life without white fat: a transgenic mouse

    Jaideep Moitra;Mark M. Mason;Michelle Olive;Dmitry Krylov

  • Hydroxylation of warfarin by human cDNA-expressed cytochrome P-450: a role for P-4502C9 in the etiology of (S)-warfarin-drug interactions.

    A E Rettie;K R Korzekwa;K L Kunze;R F Lawrence

  • Constitutive Regulation of Cardiac Fatty Acid Metabolism through Peroxisome Proliferator-activated Receptor α Associated with Age-dependent Cardiac Toxicity

    Kenichi Watanabe;Hiroshi Fujii;Toshihiro Takahashi;Makoto Kodama

  • Lidocaine metabolism in human liver microsomes by cytochrome P450IIIA4

    Mario J Bargetzi;Toshifumi Aoyama;Frank J Gonzalez;Urs A Meyer

  • Highly purified eicosapentaenoic acid treatment improves nonalcoholic steatohepatitis.

    Naoki Tanaka;Kenji Sano;Akira Horiuchi;Eiji Tanaka

  • Peroxisome proliferator-activated receptor alpha protects against alcohol-induced liver damage.

    Tamie Nakajima;Yuji Kamijo;Naoki Tanaka;Eiko Sugiyama

  • PPARα activation is essential for HCV core protein–induced hepatic steatosis and hepatocellular carcinoma in mice

    Naoki Tanaka;Kyoji Moriya;Kendo Kiyosawa;Kazuhiko Koike

  • Peroxisome proliferator‐activated receptor α protects against alcohol‐induced liver damage

    Tamie Nakajima;Tamie Nakajima;Yuji Kamijo;Yuji Kamijo;Naoki Tanaka;Naoki Tanaka;Eiko Sugiyama;Eiko Sugiyama

  • Targeting nuclear receptors for the treatment of fatty liver disease.

    Naoki Tanaka;Toshifumi Aoyama;Shioko Kimura;Frank J. Gonzalez

  • cDNA cloning and sequence and cDNA-directed expression of human P450 IIB1: identification of a normal and two variant cDNAs derived from the CYP2B locus on chromosome 19 and differential expression of the IIB mRNAs in human liver.

    S Yamano;P T Nhamburo;T Aoyama;U A Meyer

  • MOLECULAR CLONING OF CDNA ENCODING RAT VERY LONG-CHAIN ACYL-COA SYNTHETASE

    Atsushi Uchiyama;Toshifumi Aoyama;Keiju Kamijo;Yasushi Uchida

  • Sesamin, a sesame lignan, is a potent inducer of hepatic fatty acid oxidation in the rat.

    Lakshmikuttyamma Ashakumary;Isabelle Rouyer;Yoko Takahashi;Takashi Ide

  • Comparative effects of perilla and fish oils on the activity and gene expression of fatty acid oxidation enzymes in rat liver.

    Takashi Ide;Hideyuki Kobayashi;Lakshmikuttyamma Ashakumary;Isabelle A. Rouyer

  • Identification of a new variant CYP2D6 allele lacking the codon encoding Lys-281: possible association with the poor metabolizer phenotype.

    Rachel Tyndale;Toshifumi Aoyama;Franck Broly;Tamihide Matsunaga

  • Role of peroxisome proliferator-activated receptor alpha in altered cell cycle regulation in mouse liver.

    Jeffrey Maurice Peters;Toshifumi Aoyama;Russell C. Cattley;Usuda Nobumitsu

  • Di(2-ethylhexyl)phthalate Induces Hepatic Tumorigenesis through a Peroxisome Proliferator-activated Receptor α-independent Pathway

    Yuki Ito;Osamu Yamanoshita;Nobuyuki Asaeda;Yoshiaki Tagawa

  • Estradiol metabolism by complementary deoxyribonucleic acid-expressed human cytochrome P450s.

    Toshifumi Aoyama;Kenneth Korzekwa;Kiyoshi Nagata;James Gillette

  • A novel disease with deficiency of mitochondrial very-long-chain Acyl-CoA dehydrogenase

    Toshifumi Aoyama;Yasushi Uchida;Richard I. Kelley;Michael Marble

Frequent Co-Authors

Takashi Hashimoto
Takashi Hashimoto Shinshu University
Frank J. Gonzalez
Frank J. Gonzalez National Institutes of Health
Harry V. Gelboin
Harry V. Gelboin National Institutes of Health
Tadao Orii
Tadao Orii Gifu University
Seiji Yamaguchi
Seiji Yamaguchi Shimane University
Naomi Kondo
Naomi Kondo Gifu University
Reiji Kannagi
Reiji Kannagi Academia Sinica
Yoshimitsu Fukushima
Yoshimitsu Fukushima Shinshu University
Jun Nakayama
Jun Nakayama Shinshu University
Eiji Tanaka
Eiji Tanaka Shinshu University

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