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Roger E. McLendon

Roger E. McLendon

D-Index & Metrics

Medicine

D-Index
129
Citations
95522
World Ranking
2524
National Ranking
1422

Overview

Roger E. McLendon is affiliated with Duke University in the United States and has focused their research primarily in the fields of Medicine and Biochemistry, Genetics and Molecular Biology. Their work spans subfields including Molecular Biology, Genetics, Immunology, Oncology, and Radiology, Nuclear Medicine and Imaging.

The scientist's research topics encompass a range of specialized areas such as:

  • Glioma Diagnosis and Treatment
  • Chromatin Remodeling and Cancer
  • CAR-T cell therapy research
  • Radiomics and Machine Learning in Medical Imaging
  • Hedgehog Signaling Pathway Studies
  • Epigenetics and DNA Methylation
  • Neuroblastoma Research and Treatments

Roger E. McLendon has contributed to several recent papers, including:

  • Failure of human rhombic lip differentiation underlies medulloblastoma formation, 2022, Nature
  • Very low mutation burden is a feature of inflamed recurrent glioblastomas responsive to cancer immunotherapy, 2021, Nature Communications
  • The integrated genomic and epigenomic landscape of brainstem glioma, 2020, Nature Communications
  • The transcriptional landscape of Shh medulloblastoma, 2021, Nature Communications
  • Clinical Outcomes and Patient-Matched Molecular Composition of Relapsed Medulloblastoma, 2021, Journal of Clinical Oncology

The frequent coauthors collaborating with Roger E. McLendon include:

  • David M. Ashley
  • Annick Desjardins
  • Darell D. Bigner
  • Michael C. Brown
  • Simon G. Gregory

In terms of publication venues, their work has appeared regularly in:

  • Neuro-Oncology
  • UNC Libraries
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Communications
  • Nature

Best Publications

  • Glioma stem cells promote radioresistance by preferential activation of the DNA damage response

    Shideng Bao;Qiulian Wu;Roger E McLendon;Yueling Hao

  • Comprehensive genomic characterization defines human glioblastoma genes and core pathways

    Roger McLendon;Allan Friedman;Darrell Bigner;Erwin G. Van Meir

  • An Integrated Genomic Analysis of Human Glioblastoma Multiforme

    D. Williams Parsons;Siân Jones;Xiaosong Zhang;Jimmy Cheng-Ho Lin

  • IDH1 and IDH2 Mutations in Gliomas

    Hai Yan;D. Williams Parsons;Genglin Jin;Roger McLendon

  • Comprehensive, Integrative Genomic Analysis of Diffuse Lower-Grade Gliomas.

    Daniel J. Brat;Roel G.W. Verhaak;Kenneth D. Aldape;W. K.Alfred Yung

  • Cell-of-Origin Patterns Dominate the Molecular Classification of 10,000 Tumors from 33 Types of Cancer.

    Katherine A. Hoadley;Christina Yau;Christina Yau;Toshinori Hinoue;Denise M. Wolf

  • Stem cell-like glioma cells promote tumor angiogenesis through vascular endothelial growth factor

    Shideng Bao;Qiulian Wu;Sith Sathornsumetee;Yueling Hao

  • Hypoxia-Inducible Factors Regulate Tumorigenic Capacity of Glioma Stem Cells

    Zhizhong Li;Shideng Bao;Shideng Bao;Qiulian Wu;Qiulian Wu;Hui Wang

  • TERT promoter mutations occur frequently in gliomas and a subset of tumors derived from cells with low rates of self-renewal

    Patrick J. Killela;Zachary J. Reitman;Yuchen Jiao;Chetan Bettegowda

  • Altered Telomeres in Tumors with ATRX and DAXX Mutations

    Christopher M. Heaphy;Roeland F. de Wilde;Yuchen Jiao;Alison P. Klein

  • Genomic and Functional Approaches to Understanding Cancer Aneuploidy

    Alison M. Taylor;Alison M. Taylor;Juliann Shih;Gavin Ha;Gavin Ha;Galen F. Gao

  • Prasugrel versus clopidogrel for acute coronary syndromes without revascularization

    Matthew T. Roe;Paul W. Armstrong;Keith A.A. Fox;Harvey D. White

  • Subgroup-specific structural variation across 1,000 medulloblastoma genomes

    Paul A. Northcott;Paul A. Northcott;David J.H. Shih;John Peacock;Livia Garzia

  • Periostin secreted by glioblastoma stem cells recruits M2 tumour-associated macrophages and promotes malignant growth

    Wenchao Zhou;Susan Q. Ke;Zhi Huang;William Flavahan

  • The whole-genome landscape of medulloblastoma subtypes

    Paul A. Northcott;Paul A. Northcott;Ivo Buchhalter;Ivo Buchhalter;A. Sorana Morrissy;Volker Hovestadt

  • Glioblastoma Stem Cells Generate Vascular Pericytes to Support Vessel Function and Tumor Growth

    Lin Cheng;Zhi Huang;Wenchao Zhou;Qiulian Wu

  • Immunologic Escape After Prolonged Progression-Free Survival With Epidermal Growth Factor Receptor Variant III Peptide Vaccination in Patients With Newly Diagnosed Glioblastoma

    John H. Sampson;Amy B Heimberger;Gary E. Archer;Kenneth D. Aldape

  • The Hypoxic Microenvironment Maintains Glioblastoma Stem Cells and Promotes Reprogramming towards a Cancer Stem Cell Phenotype

    John M. Heddleston;Zhizhong Li;Roger E. McLendon;Anita B. Hjelmeland

  • Phase II Trial of Gefitinib in Recurrent Glioblastoma

    Jeremy N. Rich;David A. Reardon;Terry Peery;Jeannette M. Dowell

  • TERT PROMOTER MUTATIONS OCCUR FREQUENTLY IN GLIOMAS AND A SUBSET OF TUMORS DERIVED FROM CELLS WITH LOW RATES OF SELF-RENEWAL

    Hai Yan;P.J. Killela;Z.J. Reitman;Y. Jiao

Frequent Co-Authors

Darell D. Bigner
Darell D. Bigner Duke University
Henry S. Friedman
Henry S. Friedman Duke University
Allan H. Friedman
Allan H. Friedman Duke University
James E. Herndon
James E. Herndon Duke University
Jeremy N. Rich
Jeremy N. Rich University of Pittsburgh
John H. Sampson
John H. Sampson Duke University
David A. Reardon
David A. Reardon Harvard University
James J. Vredenburgh
James J. Vredenburgh Yale School of Medicine
Gary E. Archer
Gary E. Archer Duke University
James M. Provenzale
James M. Provenzale Duke University

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