World's Best Scientists 2026 revealed!

D-Index & Metrics

Chemistry

D-Index
49
Citations
8060
World Ranking
14888
National Ranking
831

Research.com Recognitions

  • 1990 - Edward Harrison Memorial Prize, Royal Society of Chemistry (UK)

Overview

Luet-Lok Wong is affiliated with the University of Oxford in the United Kingdom. Their research spans multiple scientific disciplines, with a primary focus on Materials Science, Biochemistry, Genetics and Molecular Biology, and Chemistry. The scientist's work includes significant contributions to subfields such as Materials Chemistry, Molecular Biology, Organic Chemistry, Pharmacology, and Computational Theory and Mathematics.

The research conducted by Luet-Lok Wong covers a variety of topics, including Crystallization and Solubility Studies, X-ray Diffraction in Crystallography, Pharmacogenetics and Drug Metabolism, Computational Drug Discovery Methods, Enzyme Catalysis and Immobilization, Asymmetric Hydrogenation and Catalysis, and Catalytic C-H Functionalization Methods.

Notable recent publications demonstrate a range of interdisciplinary scientific inquiries. These include:

  • Oxidative Diversification of Steroids by Nature-Inspired Scanning Glycine Mutagenesis of P450BM3 (CYP102A1), 2020, ACS Catalysis
  • Cryo-EM structure of trimeric Mycobacterium smegmatis succinate dehydrogenase with a membrane-anchor SdhF, 2020, Nature Communications
  • Enantioselective oxidation of unactivated C-H bonds in cyclic amines by iterative docking-guided mutagenesis of P450BM3 (CYP102A1), 2022, Nature Synthesis
  • Selective P450BM3 Hydroxylation of Cyclobutylamine and Bicyclo[1.1.1]pentylamine Derivatives: Underpinning Synthetic Chemistry for Drug Discovery, 2023, Journal of the American Chemical Society
  • Biophysical Techniques for Distinguishing Ligand Binding Modes in Cytochrome P450 Monooxygenases, 2020, Biochemistry

Frequent collaborators include Jeremy Robertson, Lucy A. Harwood, Ziyue Xiong, Kirsten E. Christensen, and Ruiyao Wang. The scientist has published multiple times in established venues such as The Cambridge Structural Database, Nature Communications, Organic Letters, ACS Catalysis, and the Journal of the American Chemical Society.

In 1990, Luet-Lok Wong received the Edward Harrison Memorial Prize from the Royal Society of Chemistry (UK).

Best Publications

  • Carbon-hydrogen-transition metal bonds

    M. Brookhart;M. L. H. Green;Luet-Lok Wong

  • Design of Wide-Spectrum Inhibitors Targeting Coronavirus Main Proteases

    Haitao Yang;Weiqing Xie;Xiaoyu Xue;Xiaoyu Xue;Kailin Yang;Kailin Yang

  • P450BM3 (CYP102A1): connecting the dots

    Christopher J. C. Whitehouse;Stephen G. Bell;Luet-Lok Wong

  • Protein engineering of Bacillus megaterium CYP102. The oxidation of polycyclic aromatic hydrocarbons.

    Angus B. Carmichael;Luet-Lok Wong

  • Biotransformation of the sesquiterpene (+)-valencene by cytochrome P450cam and P450BM-3

    Rebecca J. Sowden;Samina Yasmin;Nicholas H. Rees;Stephen G. Bell

  • Protein engineering of cytochrome P450cam (CYP101) for the oxidation of polycyclic aromatic hydrocarbons

    Charles F. Harford-Cross;Angus B. Carmichael;Fiona K. Allan;Paul A. England

  • An electron transfer path connects subunits of a mycobacterial respiratory supercomplex.

    Hongri Gong;Jun Li;Jun Li;Ao Xu;Ao Xu;Yanting Tang

  • Molecular recognition in (+)-alpha-pinene oxidation by cytochrome P450cam

    Stephen G. Bell;Xuehui Chen;Rebecca J. Sowden;Feng Xu

  • Crystal Structures of Human Glycerol 3-phosphate Dehydrogenase 1 (GPD1)

    Xianjin Ou;Chaoneng Ji;Xueqing Han;Xiaodong Zhao

  • Crystal structure of human pirin: an iron-binding nuclear protein and transcription cofactor.

    Hai Pang;Mark Bartlam;Qinghong Zeng;Hideyuki Miyatake

  • Redox properties of cytochrome P450BM3 measured by direct methods

    Barry D. Fleming;Yanni Tian;Stephen G. Bell;Luet-Lok Wong

  • The heme monooxygenase cytochrome P450cam can be engineered to oxidize ethane to ethanol.

    Feng Xu;Stephen G. Bell;Jaka Lednik;Andrew Insley

  • RELATIONSHIP BETWEEN INTRAMOLECULAR CHEMICAL-EXCHANGE AND NMR-OBSERVED RATE CONSTANTS

    Malcolm L. H. Green;Luet Lok Wong;Andrea Sella

  • Evolved CYP102A1 (P450BM3) variants oxidise a range of non-natural substrates and offer new selectivity options

    Christopher J. C. Whitehouse;Stephen G. Bell;Henry G. Tufton;Richard J. P. Kenny

  • Oxidation of polychlorinated benzenes by genetically engineered CYP101 (cytochrome P450cam)

    Jonathan P. Jones;Ellen J. O'Hare;Luet-Lok Wong

  • Structural information from orientationally selective DEER spectroscopy

    J. E. Lovett;A. M. Bowen;C. R. Timmel;M. W. Jones

  • Direct electrochemistry of cytochrome P450cam

    Jurate Kazlauskaite;Andrew C. G. Westlake;Luet-Lok Wong;H. Allen O. Hill

  • The catalytic activity of cytochrome P450cam towards styrene oxidation is increased by site-specific mutagenesis

    Darren P Nickerson;Charles F Harford-Cross;Sarah R Fulcher;Luet-Lok Wong

  • Surface-modified mutants of cytochrome P450cam: enzymatic properties and electrochemistry.

    Kenneth Kam-Wing Lo;Luet-Lok Wong;H.Allen O Hill

  • The oxidation of naphthalene and pyrene by cytochrome P450cam

    Paul A England;Charles F Harford-Cross;Julie-Anne Stevenson;Duncan A Rouch

  • Butane and propane oxidation by engineered cytochrome P450cam.

    Stephen G. Bell;Julie-Anne Stevenson;Helen D. Boyd;Sophie Campbell

Frequent Co-Authors

Zihe Rao
Zihe Rao Tsinghua University
Malcolm L. H. Green
Malcolm L. H. Green University of Oxford
Mark Bartlam
Mark Bartlam Nankai University
H. Allen O. Hill
H. Allen O. Hill University of Oxford
Wen Yang
Wen Yang Beijing Institute of Technology
Dermot O'Hare
Dermot O'Hare University of Oxford
Philip Mountford
Philip Mountford University of Oxford
Kenneth Kam-Wing Lo
Kenneth Kam-Wing Lo City University of Hong Kong
Luke W. Guddat
Luke W. Guddat University of Queensland
Guanghou Shui
Guanghou Shui Chinese Academy of Sciences

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

Studying Chemistry in the USA opens doors to a variety of exciting career pathways beyond traditional laboratory roles. Many graduates explore fields where their scientific knowledge can be applied in practical, impactful ways.

For those interested in legal aspects of science, pursuing a paralegal degree can be a rewarding option. Understanding the nuances of legal documentation and procedures can lead to promising opportunities, with insights into paralegal salary often reflecting the demand for specialized expertise.

Chemistry graduates may also consider careers in the pharmaceutical industry. Becoming a pharmaceutical sales representative combines scientific understanding with communication skills. To learn more about this pathway and earning potential, check out this guide on pharma sales rep salary.

For those dedicated to healthcare, the journey to becoming a pharmacist remains a respectable yet challenging option, requiring rigorous study and training. Learn what it takes and the realities involved by exploring the article on is it hard to become a pharmacist.

Finally, for individuals fascinated by forensic science, a role as an autopsy technician offers a unique blend of biology and investigative work. Information about the educational requirements and earning potential can be found by reviewing the details about autopsy technician salary.

Best Scientists Citing Luet-Lok Wong

Trending Scientists

Recently Published Articles