World's Best Scientists 2026 revealed!
Rita Bernhardt

Rita Bernhardt

D-Index & Metrics

Chemistry

D-Index
60
Citations
13324
World Ranking
9666
National Ranking
694

Biology and Biochemistry

D-Index
62
Citations
13902
World Ranking
10790
National Ranking
776

Overview

Rita Bernhardt is affiliated with Saarland University in Germany and has contributed extensively to the fields of Medicine and Biochemistry, Genetics, and Molecular Biology. Their research covers a broad range of subfields, including Molecular Biology, Pharmacology, Endocrinology, Diabetes and Metabolism, Neurology, and Cellular and Molecular Neuroscience.

The scientist's work addresses several main topics, with a strong focus on Pharmacogenetics and Drug Metabolism, Hormonal Regulation and Hypertension, and Steroid Chemistry and Biochemistry. Additional areas of research include Parkinson's Disease Mechanisms and Treatments, Nuclear Receptors and Signaling, Neurological diseases and metabolism, and Antifungal resistance and susceptibility.

Among their recent publications are:

  • Redox Partners: Function Modulators of Bacterial P450 Enzymes, 2020, Trends in Microbiology
  • Development and application of a highly efficient CRISPR-Cas9 system for genome engineering in Bacillus megaterium, 2021, Journal of Biotechnology
  • Resurrection and characterization of ancestral CYP11A1 enzymes, 2021, FEBS Journal
  • Synthesis, Optimization, Antifungal Activity, Selectivity, and CYP51 Binding of New 2-Aryl-3-azolyl-1-indolyl-propan-2-ols, 2020, Pharmaceuticals
  • A CYPome-wide study reveals new potential players in the pathogenesis of Parkinson's disease, 2023, Frontiers in Pharmacology

Frequent coauthors collaborating with Bernhardt include Philip Hartz, Frank Hannemann, Michael C. Hutter, Fabrice Pagniez, and Patrícia Recordon-Pinson.

The scientist publishes regularly in several key venues, most notably the Journal of Biotechnology and Frontiers in Pharmacology, both with three publications each, followed by FEBS Journal and The Cambridge Structural Database with two publications each, and Trends in Microbiology with one publication.

Best Publications

  • Cytochromes P450 as versatile biocatalysts.

    Rita Bernhardt

  • Cytochrome P450 systems--biological variations of electron transport chains.

    Frank Hannemann;Andreas Bichet;Kerstin M. Ewen;Rita Bernhardt

  • Cytochromes P450 as promising catalysts for biotechnological application: chances and limitations.

    Rita Bernhardt;Vlada B. Urlacher

  • Humans possess two mitochondrial ferredoxins, Fdx1 and Fdx2, with distinct roles in steroidogenesis, heme, and Fe/S cluster biosynthesis.

    Alex D. Sheftel;Oliver Stehling;Antonio J. Pierik;Hans-Peter Elsässer

  • Influence of grain germination on functional properties of sorghum flour

    Abd Elmoneim O. Elkhalifa;Rita Bernhardt

  • Adrenodoxin: Structure, stability, and electron transfer properties

    Asya V. Grinberg;Frank Hannemann;Burkhard Schiffler;Jürgen Müller

  • Effect of fermentation on the functional properties of sorghum flour

    Abd Elmoneim O. Elkhalifa;B. Schiffler;R. Bernhardt

  • New aspects of electron transfer revealed by the crystal structure of a truncated bovine adrenodoxin, Adx(4–108)

    Alexander Müller;Jürgen J Müller;Yves A Muller;Heike Uhlmann

  • Selected Physicochemical Properties of Starch Isolated from Fermented Sorghum Flour

    Abd Elmoneim O. Elkhalifa;Abd Elmoneim O. Elkhalifa;Burkhard Schiffler;Rita Bernhardt

  • Cytochrome P450: Structure, function, and generation of reactive oxygen species

    Unknown

  • C-terminal region of adrenodoxin affects its structural integrity and determines differences in its electron transfer function to cytochrome P-450.

    H Uhlmann;R Kraft;R Bernhardt

  • Redox Partners: Function Modulators of Bacterial P450 Enzymes.

    Shengying Li;Lei Du;Lei Du;Rita Bernhardt

  • CYP17- and CYP11B-dependent steroid hydroxylases as drug development targets.

    Tarek Hakki;Rita Bernhardt

  • Modulation of aldosterone and cortisol synthesis on the molecular level

    Michael Lisurek;Rita Bernhardt

  • Characterization of the versatile monooxygenase CYP109B1 from Bacillus subtilis

    Marco Girhard;Tobias Klaus;Yogan Khatri;Rita Bernhardt

  • Functional expression of human mitochondrial CYP11B2 in fission yeast and identification of a new internal electron transfer protein, etp1

    Matthias Bureik;Burkhard Schiffler;Yasushi Hiraoka;Frank Vogel

  • Towards preparative scale steroid hydroxylation with cytochrome P450 monooxygenase CYP106A2.

    Daniela Zehentgruber;Frank Hannemann;Sabrina Bleif;Rita Bernhardt

  • Adrenodoxin: The archetype of vertebrate-type [2Fe–2S] cluster ferredoxins

    Kerstin Maria Ewen;Michael Kleser;Rita Bernhardt

  • The role of sulfated steroid hormones in reproductive processes.

    Joachim Geyer;Katharina Bakhaus;Rita Bernhardt;Carina Blaschka

  • The human steroid hydroxylases CYP1B1 and CYP11B2.

    Matthias Bureik;Michael Lisurek;Rita Bernhardt

  • Dynamics in a Pure Encounter Complex of Two Proteins Studied by Solution Scattering and Paramagnetic NMR Spectroscopy

    Xingfu Xu;Wolfgang Reinle;Frank Hannemann;Peter V. Konarev

  • Cellular surface display of dimeric Adx and whole cell P450-mediated steroid synthesis on E. coli.

    Joachim Jose;Rita Bernhardt;Frank Hannemann

Frequent Co-Authors

Vlada B. Urlacher
Vlada B. Urlacher Heinrich Heine University Düsseldorf
Udo Heinemann
Udo Heinemann Max Delbrück Center for Molecular Medicine
Rolf W. Hartmann
Rolf W. Hartmann Helmholtz Centre for Infection Research
Marcellus Ubbink
Marcellus Ubbink Leiden University
Alexander I. Archakov
Alexander I. Archakov Pirogov Russian National Research Medical University
Christian G. Huber
Christian G. Huber University of Salzburg
Rolf Müller
Rolf Müller Saarland University
Jean-Marc Pascussi
Jean-Marc Pascussi University of Montpellier
Michael R. Waterman
Michael R. Waterman Vanderbilt University
Alain Van Dorsselaer
Alain Van Dorsselaer University of Strasbourg

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