What is he best known for?
The fields of study he is best known for:
- Enzyme
- Gene
- Organic chemistry
Rolf W. Hartmann spends much of his time researching Enzyme, Stereochemistry, Enzyme inhibitor, Chemical synthesis and Biochemistry.
The study incorporates disciplines such as In vitro, Estrogen, Aldosterone synthase and In vivo in addition to Enzyme.
His Stereochemistry research incorporates themes from Selectivity, IC50, Aromatase and Structure–activity relationship.
His Aromatase research includes themes of Lyase and Pharmacology.
His Enzyme inhibitor study which covers Bicyclic molecule that intersects with Ether cleavage, Molecule, Heme and Aldol condensation.
His study explores the link between Chemical synthesis and topics such as Docking that cross with problems in Active site.
His most cited work include:
- 17β-Hydroxysteroid dehydrogenases (17β-HSDs) as therapeutic targets: protein structures, functions, and recent progress in inhibitor development. (145 citations)
- Novel Strategies for the Treatment of Pseudomonas aeruginosa Infections (117 citations)
- Antibiotic-free nanotherapeutics: ultra-small, mucus-penetrating solid lipid nanoparticles enhance the pulmonary delivery and anti-virulence efficacy of novel quorum sensing inhibitors. (104 citations)
What are the main themes of his work throughout his whole career to date?
The scientist’s investigation covers issues in Stereochemistry, Enzyme, Biochemistry, Aromatase and Pharmacology.
His Stereochemistry research is multidisciplinary, incorporating perspectives in Biological activity, Selectivity, Steroid, Structure–activity relationship and Enzyme inhibitor.
His work in Enzyme inhibitor covers topics such as Chemical synthesis which are related to areas like Docking.
His work is dedicated to discovering how Enzyme, Aldosterone synthase are connected with Aldosterone and other disciplines.
His research investigates the connection between Biochemistry and topics such as Pseudomonas aeruginosa that intersect with problems in Pyocyanin.
His Pharmacology research is multidisciplinary, incorporating elements of In vivo, Breast cancer and Steroid 11-beta-hydroxylase.
He most often published in these fields:
- Stereochemistry (38.19%)
- Enzyme (26.63%)
- Biochemistry (22.61%)
What were the highlights of his more recent work (between 2013-2021)?
- Biochemistry (22.61%)
- Stereochemistry (38.19%)
- Pharmacology (14.07%)
In recent papers he was focusing on the following fields of study:
His main research concerns Biochemistry, Stereochemistry, Pharmacology, Pseudomonas aeruginosa and Microbiology.
His work on Substituent as part of general Stereochemistry study is frequently connected to Linker, therefore bridging the gap between diverse disciplines of science and establishing a new relationship between them.
His Pharmacology study incorporates themes from Aldosterone, Aromatase, Aldosterone synthase, IC50 and Steroid 11-beta-hydroxylase.
Rolf W. Hartmann has researched Pseudomonas aeruginosa in several fields, including Quorum sensing, Virulence factor, Virulence and Cystic fibrosis.
The various areas that Rolf W. Hartmann examines in his Microbiology study include Pseudomonas aeruginosa Infections, In vivo and Biofilm.
His Enzyme study integrates concerns from other disciplines, such as In vitro and Moiety.
Between 2013 and 2021, his most popular works were:
- Novel Strategies for the Treatment of Pseudomonas aeruginosa Infections (117 citations)
- Antibiotic-free nanotherapeutics: ultra-small, mucus-penetrating solid lipid nanoparticles enhance the pulmonary delivery and anti-virulence efficacy of novel quorum sensing inhibitors. (104 citations)
- Overcoming the unexpected functional inversion of a PqsR antagonist in Pseudomonas aeruginosa: an in vivo potent antivirulence agent targeting pqs quorum sensing. (65 citations)
In his most recent research, the most cited papers focused on:
- Enzyme
- Gene
- Organic chemistry
His primary areas of study are Biochemistry, Pseudomonas aeruginosa, Quorum sensing, Stereochemistry and Microbiology.
Enzyme, Mutant, IC50, Small molecule and Kinase are among the areas of Biochemistry where Rolf W. Hartmann concentrates his study.
His study in the fields of Biosynthesis under the domain of Enzyme overlaps with other disciplines such as Linker.
His Pseudomonas aeruginosa research integrates issues from In vitro, Structure–activity relationship, In vivo and Biofilm.
He combines subjects such as Virulence factor and Cell signaling with his study of Quorum sensing.
His work carried out in the field of Stereochemistry brings together such families of science as Polymerase, Lead compound, Mode of action, Selectivity and Steroid 11-beta-hydroxylase.
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