World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
61
Citations
10834
World Ranking
11558
National Ranking
418

Overview

Claude Cochet is affiliated with Grenoble Alpes University in France, focusing research primarily within the fields of Medicine and Biochemistry, Genetics and Molecular Biology. Their work spans multiple subfields, including Molecular Biology, Pulmonary and Respiratory Medicine, Oncology, Biomedical Engineering, and Cell Biology.

The scientist's research covers a range of topics, most notably in renal and related cancers. Specific areas of investigation include renal cell carcinoma treatment, protein kinase regulation and GTPase signaling, 3D printing in biomedical research, cancer cells and metastasis, PI3K/AKT/mTOR signaling in cancer, and ferroptosis and cancer prognosis.

Claude Cochet has contributed to several publications, with research appearing frequently in key venues such as:

  • Cancers
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Immunology
  • Molecular and Cellular Biochemistry
  • iScience

Recent papers include:

  • Ex-Vivo Treatment of Tumor Tissue Slices as a Predictive Preclinical Method to Evaluate Targeted Therapies for Patients with Renal Carcinoma, 2020, published in Cancers
  • CIGB-300 anticancer peptide regulates the protein kinase CK2-dependent phosphoproteome, 2020, published in Molecular and Cellular Biochemistry
  • Cooperative Blockade of CK2 and ATM Kinases Drives Apoptosis in VHL-Deficient Renal Carcinoma Cells through ROS Overproduction, 2021, published in Cancers
  • COL7A1 Expression Improves Prognosis Prediction for Patients with Clear Cell Renal Cell Carcinoma Atop of Stage, 2023, published in Cancers
  • Cancer selective cell death induction by a bivalent CK2 inhibitor targeting the ATP site and the allosteric αD pocket, 2024, published in iScience

Collaboration is a significant aspect of their research activities, with frequent co-authors including Odile Filhol, Catherine Pillet, Christophe Battail, Caroline Roelants, and Laurent Guyon. These collaborations have been reflected in multiple joint publications.

Best Publications

  • A structural basis for substrate specificities of protein Ser/Thr kinases: primary sequence preference of casein kinases I and II, NIMA, phosphorylase kinase, calmodulin-dependent kinase II, CDK5, and Erk1.

    Z. Songyang;Kun Ping Lu;Young T. Kwon;Li Huei Tsai

  • Monoclonal anti-epidermal growth factor receptor antibodies which are inhibitors of epidermal growth factor binding and antagonists of epidermal growth factor binding and antagonists of epidermal growth factor-stimulated tyrosine protein kinase activity.

    G N Gill;T Kawamoto;C Cochet;A Le

  • Joining the cell survival squad: an emerging role for protein kinase CK2.

    Khalil Ahmed;Delphine A Gerber;Claude Cochet

  • Disruption of the regulatory beta subunit of protein kinase CK2 in mice leads to a cell-autonomous defect and early embryonic lethality.

    Thierry Buchou;Muriel Vernet;Olivier Blond;Hans H Jensen

  • Demonstration of epidermal growth factor-induced receptor dimerization in living cells using a chemical covalent cross-linking agent.

    C Cochet;O Kashles;E M Chambaz;I Borrello

  • Selectivity, Cocrystal Structures, and Neuroprotective Properties of Leucettines, a Family of Protein Kinase Inhibitors Derived from the Marine Sponge Alkaloid Leucettamine B.

    Tania Tahtouh;Jonathan M. Elkins;Panagis Filippakopoulos;Meera Soundararajan

  • Crystal structure of the human protein kinase CK2 regulatory subunit reveals its zinc finger-mediated dimerization.

    Laurent Chantalat;Didier Leroy;Odile Filhol;Arsenio Nueda

  • Identification of Polyoxometalates as Nanomolar Noncompetitive Inhibitors of Protein Kinase CK2

    Renaud Prudent;Virginie Moucadel;Béatrice Laudet;Caroline Barette

  • Fibroblast Growth Factor-2 Binds to the Regulatory β Subunit of CK2 and Directly Stimulates CK2 Activity toward Nucleolin

    Hélène Bonnet;Odile Filhol;Isabelle Truchet;Philippe Brethenou

  • Nuclear localization of protein kinase CK2 catalytic subunit (CK2α) is associated with poor prognostic factors in human prostate cancer

    Mathieu Laramas;Dominique Pasquier;Odile Filhol;François Ringeisen

  • Protein kinase CK2 in health and disease: Cellular functions of protein kinase CK2: a dynamic affair.

    O. Filhol;C. Cochet

  • PHOSPHORYLATION BY CK2 AND MAPK ENHANCES CALNEXIN ASSOCIATION WITH RIBOSOMES

    E. Chevet;H.N. Wong;D. Gerber;C. Cochet

  • Live-Cell Fluorescence Imaging Reveals the Dynamics of Protein Kinase CK2 Individual Subunits

    Odile Filhol;Arsenio Nueda;Véronique Martel;Delphine Gerber-Scokaert

  • Interaction between the epidermal growth factor receptor and phosphoinositide kinases.

    C Cochet;O Filhol;B Payrastre;T Hunter

  • Protein kinase CK2: a new view of an old molecular complex

    Odile Filhol;Jean-Louis Martiel;Claude Cochet

  • Polyamine-mediated protein phosphorylations: A possible target for intracellular polyamine action

    Claude Cochet;Edmond M. Chambaz

  • Binding of Polyamines to an Autonomous Domain of the Regulatory Subunit of Protein Kinase CK2 Induces a Conformational Change in the Holoenzyme A PROPOSED ROLE FOR THE KINASE STIMULATION

    Didier Leroy;Jean-Karim Heriché;Odile Filhol;Edmond M. Chambaz

  • Casein kinase II and the tumor suppressor protein P53 associate in a molecular complex that is negatively regulated upon P53 phosphorylation.

    O Filhol;J Baudier;C Delphin;P Loue-Mackenbach

  • Selective inhibition of a cyclic nucleotide independent protein kinase (G type casein kinase) by quercetin and related polyphenols.

    C. Cochet;J.J. Feige;F. Pirollet;M. Keramidas

  • New Protein Kinase CK2 Inhibitors : Jumping out of the Catalytic Box

    Renaud Prudent;Claude Cochet

Frequent Co-Authors

Jean-Jacques Feige
Jean-Jacques Feige Grenoble Alpes University
Didier Job
Didier Job Grenoble Alpes University
Jacques Baudier
Jacques Baudier Aix-Marseille University
Ruben Abagyan
Ruben Abagyan University of California, San Diego
Stefan Knapp
Stefan Knapp Goethe University Frankfurt
Panagis Filippakopoulos
Panagis Filippakopoulos Structural Genomics Consortium
Alex N. Bullock
Alex N. Bullock University of Oxford
Otto Dideberg
Otto Dideberg Centre national de la recherche scientifique, CNRS
Olivier Hermine
Olivier Hermine Necker-Enfants Malades Hospital

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Best Scientists Citing Claude Cochet

Trending Scientists