Flavio Meggio

Overview

Best Publications

• One-thousand-and-one substrates of protein kinase CK2?

  Flavio Meggio;Lorenzo A. Pinna

  1599
  Citations

• Selectivity of 4,5,6,7-tetrabromobenzotriazole, an ATP site-directed inhibitor of protein kinase CK2 ('casein kinase-2').

  Stefania Sarno;Helen Reddy;Flavio Meggio;Maria Ruzzene

  437
  Citations

• Protein kinase CK2 ("casein kinase-2") and its implication in cell division and proliferation.

  Lorenzo A. Pinna;Flavio Meggio

  437
  Citations

• Roscovitine Targets, Protein Kinases and Pyridoxal Kinase

  Stéphane Bach;Marie Knockaert;Jens Reinhardt;Olivier Lozach

  432
  Citations

• The Protein Kinase CK2 Facilitates Repair of Chromosomal DNA Single-Strand Breaks

  Joanna I. Loizou;Sherif F. El-Khamisy;Anastasia Zlatanou;David J. Moore

  369
  Citations

• Different susceptibility of protein kinases to staurosporine inhibition Kinetic studies and molecular bases for the resistance of protein kinase CK2

  Flavio Meggio;Arianna Donella Deana;Maria Ruzzene;Anna M. Brunati

  366
  Citations

• The selectivity of inhibitors of protein kinase CK2: an update.

  Mario A Pagano;Jenny Bain;Zygmunt Kazimierczuk;Stefania Sarno

  288
  Citations

• Substrate specificity of protein kinase CK2.

  Flavio Meggio;Oriano Marin;Lorenzo Pinna

  244
  Citations

• Site specificity of casein kinase-2 (TS) from rat liver cytosol. A study with model peptide substrates.

  Oriano Marin;Flavio Meggio;Fernando Marchiori;Gianfranco Borin

  237
  Citations

• Toward the rational design of protein kinase casein kinase-2 inhibitors.

  Stefania Sarno;Stefano Moro;Flavio Meggio;Giuseppe Zagotto

  225
  Citations

• Optimization of protein kinase CK2 inhibitors derived from 4,5,6,7-tetrabromobenzimidazole.

  Mario A Pagano;Mariola Andrzejewska;Maria Ruzzene;Stefania Sarno

  224
  Citations

• 2-dimethylamino-4,5,6,7-tetrabromo-1H-benzimidazole: a novel powerful and selective inhibitor of protein kinase CK2

  Mario A. Pagano;Flavio Meggio;Maria Ruzzene;Mariola Andrzejewska

  219
  Citations

• Role of the beta subunit of casein kinase-2 on the stability and specificity of the recombinant reconstituted holoenzyme.

  Flavio Meggio;Brigitte Boldyreff;Oriano Marin;Lorenzo A. Pinna

  210
  Citations

• Endogenous phosphate acceptor proteins for rat liver cytosolic casein kinases.

  F Meggio;A D Deana;L A Pinna

  205
  Citations

• Casein kinase 2 down-regulation and activation by polybasic peptides are mediated by acidic residues in the 55-64 region of the beta-subunit. A study with calmodulin as phosphorylatable substrate.

  Flavio Meggio;Brigitte Boldyreff;Olaf-Georg Issinger;Lorenzo A. Pinna

  192
  Citations

• Identification of ellagic acid as potent inhibitor of protein kinase CK2: a successful example of a virtual screening application.

  Giorgio Cozza;Paolo Bonvini;Elisa Zorzi;Giorgia Poletto

  192
  Citations

• QUINALIZARIN AS A POTENT, SELECTIVE AND CELL PERMEABLE INHIBITOR OF PROTEIN KINASE CK2.

  Giorgio Cozza;Marco Mazzorana;Elena Papinutto;Jenny Bain

  190
  Citations

• Synthetic peptides including acidic clusters as substrates and inhibitors of rat liver casein kinase TS (type-2).

  F Meggio;F Marchiori;G Borin;G Chessa

  185
  Citations

• Unprecedented selectivity and structural determinants of a new class of protein kinase CK2 inhibitors in clinical trials for the treatment of cancer.

  Roberto Battistutta;Giorgio Cozza;Fabrice Pierre;Elena Papinutto

  184
  Citations

• Ribofuranosyl‐benzimidazole derivatives as inhibitors of casein kinase‐2 and casein kinase‐1

  Flavio Meggio;David Shugar;Lorenzo A. Pinna

  179
  Citations