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Giuseppe Zanotti

Giuseppe Zanotti

D-Index & Metrics

Biology and Biochemistry

D-Index
51
Citations
8966
World Ranking
17209
National Ranking
546

Overview

Giuseppe Zanotti is a researcher affiliated with the University of Padua in Italy, specializing in biochemistry, genetics, and molecular biology, with additional focus on medicine. Their work emphasizes molecular biology, materials chemistry, endocrinology, cellular and molecular neuroscience, and biochemistry as core subfields.

The main research topics addressed by Zanotti include enzyme structure and function, protein structure and dynamics, botulinum toxin and related neurological disorders, diphtheria, corynebacterium, and tetanus, bacteriophages and microbial interactions, coenzyme Q10 studies and effects, and advanced battery technologies research.

Giuseppe Zanotti has published in various scientific venues, frequently contributing to bioRxiv (Cold Spring Harbor Laboratory) and the International Journal of Molecular Sciences. Other notable publication venues include Toxicon, Nature Chemical Biology, and Pharmacological Research.

Recent papers showcasing Zanotti's research activity include:

  • Atomic structure of potato virus X, the prototype of the Alphaflexiviridae family, 2020, Nature Chemical Biology
  • Aldosterone synthase inhibitors for cardiovascular diseases: A comprehensive review of preclinical, clinical and in silico data, 2020, Pharmacological Research
  • Experimentally Determined Long Intrinsically Disordered Protein Regions Are Now Abundant in the Protein Data Bank, 2020, International Journal of Molecular Sciences
  • High-Light versus Low-Light: Effects on Paired Photosystem II Supercomplex Structural Rearrangement in Pea Plants, 2020, International Journal of Molecular Sciences
  • Benzylaminoethyureido-Tailed Benzenesulfonamides: Design, Synthesis, Kinetic and X-ray Investigations on Human Carbonic Anhydrases, 2020, International Journal of Molecular Sciences

Zanotti frequently collaborates with other researchers, including Alessandro Grinzato, Giampietro Schiavo, Marco Pirazzini, Eaazhisai Kandiah, and Francesca Vallese.

Best Publications

  • Crystal structure of the trigonal form of bovine beta-lactoglobulin and of its complex with retinol at 2.5 A resolution.

    Hugo L. Monaco;Giuseppe Zanotti;Paola Spadon;Martino Bolognesi

  • Toward the rational design of protein kinase casein kinase-2 inhibitors.

    Stefania Sarno;Stefano Moro;Flavio Meggio;Giuseppe Zagotto

  • Three-dimensional structure of recombinant human muscle fatty acid-binding protein.

    G Zanotti;G Scapin;P Spadon;J.H. Veerkamp

  • Plasma retinol-binding protein: structure and interactions with retinol, retinoids, and transthyretin.

    Giuseppe Zanotti;Rodolfo Berni

  • Structural features underlying selective inhibition of protein kinase CK2 by ATP site‐directed tetrabromo‐2‐benzotriazole

    Roberto Battistutta;Erika De Moliner;Stefania Sarno;Giuseppe Zanotti

  • Structure of the Neutrophil-activating Protein from Helicobacter pylori

    Giuseppe Zanotti;Elena Papinutto;William G. Dundon;Roberto Battistutta

  • The replacement of ATP by the competitive inhibitor emodin induces conformational modifications in the catalytic site of protein kinase CK2.

    Roberto Battistutta;Stefania Sarno;Erika De Moliner;Elena Papinutto

  • Bicyclic peptide inhibitor reveals large contact interface with a protease target.

    Alessandro Angelini;Laura Cendron;Shiyu Chen;Jeremy Touati

  • Biochemical and three-dimensional-structural study of the specific inhibition of protein kinase CK2 by [5-oxo-5,6-dihydroindolo-(1,2-a)quinazolin-7-yl]acetic acid (IQA).

    Stefania Sarno;Erika De Moliner;Maria Ruzzene;Mario A. Pagano

  • Structure of Two Iron-binding Proteins from Bacillus anthracis

    Elena Papinutto;William George Dundon;N Pitulis;Roberto Battistutta

  • Crystal structure of peach Pru p 3, the prototypic member of the family of plant non-specific lipid transfer protein pan-allergens

    Nicola Pasquato;Rodolfo Berni;Claudia Folli;Silvia Folloni

  • The New Apolipoprotein A-I Variant Leu174 → Ser Causes Hereditary Cardiac Amyloidosis, and the Amyloid Fibrils Are Constituted by the 93-Residue N-Terminal Polypeptide

    Laura Obici;Vittorio Bellotti;Palma Mangione;Monica Stoppini

  • Inspecting the Structure-Activity Relationship of Protein Kinase CK2 Inhibitors Derived from Tetrabromo-Benzimidazole

    Roberto Battistutta;Marco Mazzorana;Stefania Sarno;Zygmunt Kazimierczuk

  • Helicobacter pylori secreted peptidyl prolyl cis, trans-isomerase drives Th17 inflammation in gastric adenocarcinoma

    Amedeo Amedei;Fabio Munari;Chiara Della Bella;Elena Niccolai

  • Borrelia burgdorferi NapA-Driven Th17 Cell Inflammation in Lyme Arthritis

    Gaia Codolo;Amedeo Amedei;Allen C. Steere;Elena Papinutto

  • Crystal structure of liganded and unliganded forms of bovine plasma retinol-binding protein.

    Giuseppe Zanotti;R. Berni;H. L. Monaco

  • ATP site-directed inhibitors of protein kinase CK2: an update.

    Stefania Sarno;Elena Papinutto;Cinzia Franchin;J Bain

  • The ATP-binding site of protein kinase CK2 holds a positive electrostatic area and conserved water molecules.

    Roberto Battistutta;Marco Mazzorana;Laura Cendron;Andrea Bortolato

  • Inhibition of protein kinase CK2 by anthraquinone-related compounds. A structural insight.

    Erika De Moliner;Stefano Moro;Stefania Sarno;Giuseppe Zagotto

  • Crystal structure and refolding properties of the mutant F99S/M153T/V163A of the green fluorescent protein.

    Roberto Battistutta;Alessandro Negro;Giuseppe Zanotti

Frequent Co-Authors

Stefania Sarno
Stefania Sarno University of Bologna
Lorenzo A. Pinna
Lorenzo A. Pinna University of Padua
Cesare Montecucco
Cesare Montecucco University of Padua
Mario Milco D'Elios
Mario Milco D'Elios University of Siena
Simone Ottonello
Simone Ottonello University of Parma
Stefano Moro
Stefano Moro University of Padua
Stefano Lupi
Stefano Lupi Sapienza University of Rome
Amedeo Amedei
Amedeo Amedei University of Florence
Flavio Meggio
Flavio Meggio University of Padua
Marisa Brini
Marisa Brini University of Padua

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