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Ornella Rossetto

Ornella Rossetto

D-Index & Metrics

Biology and Biochemistry

D-Index
65
Citations
15684
World Ranking
9126
National Ranking
250

Overview

Ornella Rossetto is affiliated with the University of Padua in Italy and has contributed extensively to research in medicine and biochemistry, genetics, and molecular biology. Their work primarily focuses on neurological fields, including neurology, cellular and molecular neuroscience, and molecular biology.

Their research addresses a range of neurological disorders and treatments, with particular attention to botulinum toxin and related neurological conditions. Other main topics include hereditary neurological disorders, diphtheria and tetanus-related infections, streptococcal infections and treatments, Parkinson's disease mechanisms and treatments, as well as pain mechanisms and treatments.

Notable recent publications by Rossetto include:

  • Botulinum Neurotoxins: Mechanism of Action, 2020, Handbook of Experimental Pharmacology
  • Tetanus and tetanus neurotoxin: From peripheral uptake to central nervous tissue targets, 2021, Journal of Neurochemistry
  • Toxicology and pharmacology of botulinum and tetanus neurotoxins: an update, 2022, Archives of Toxicology
  • Paper-based electrochemical peptide sensor for on-site detection of botulinum neurotoxin serotype A and C, 2021, Biosensors and Bioelectronics
  • Clinical duration of action of different botulinum toxin types in humans, 2020, Toxicon

Frequent co-authors collaborating with Rossetto include Marco Pirazzini, Cesare Montecucco, F Fabris, Aram Megighian, and Marika Tonellato. Their collaborative work has contributed to advancing understanding in the field of neurotoxins and neurological disorder treatments.

Rossetto's publications often appear in specialized journals such as Toxicon, the International Journal of Molecular Sciences, the British Journal of Pharmacology, bioRxiv (Cold Spring Harbor Laboratory), and the Journal of Neurochemistry, with Toxicon being the most common venue for their work.

Best Publications

  • Tetanus and botulinum-B neurotoxins block neurotransmitter release by proteolytic cleavage of synaptobrevin

    Giampietro G. Schiavo;Fabio Benfenati;Bernard Poulain;Ornella Rossetto

  • Botulinum Neurotoxins: Biology, Pharmacology, and Toxicology.

    Marco Pirazzini;Ornella Rossetto;Roberto Eleopra;Cesare Montecucco

  • Botulinum neurotoxins: genetic, structural and mechanistic insights

    Ornella Rossetto;Marco Pirazzini;Cesare Montecucco

  • Identification of the nerve terminal targets of botulinum neurotoxin serotypes A, D, and E.

    G Schiavo;O Rossetto;S Catsicas;P Polverino de Laureto

  • Long-Distance Retrograde Effects of Botulinum Neurotoxin A

    Flavia Antonucci;Chiara Rossi;Laura Gianfranceschi;Ornella Rossetto

  • Botulinum neurotoxin serotype F is a zinc endopeptidase specific for VAMP/synaptobrevin

    G. Schiavo;C. C. Shone;O. Rossetto;F. C. G. Alexander

  • Tetanus toxin is a zinc protein and its inhibition of neurotransmitter release and protease activity depend on zinc.

    G. Schiavo;B. Poulain;O. Rossetto;F. Benfenati

  • Tetanus and botulinum neurotoxins: mechanism of action and therapeutic uses

    Rossella Pellizzari;Ornella Rossetto;Giampietro Schiavo;Cesare Montecucco

  • Botulinum neurotoxins are zinc proteins.

    G Schiavo;O Rossetto;A Santucci;B.R. DasGupta

  • Historical perspectives and guidelines for botulinum neurotoxin subtype nomenclature

    Michael W. Peck;Theresa J. Smith;Fabrizio Anniballi;John W. Austin

  • VAMP-2 and cellubrevin are expressed in pancreatic beta-cells and are essential for Ca(2+)-but not for GTP gamma S-induced insulin secretion.

    R. Regazzi;C. B. Wollheim;Jochen Lang;J.-M. Theler

  • Common and distinct fusion proteins in axonal growth and transmitter release

    Astrid Osen-Sand;Julie K. Staple;Ezio Naldi;Giampietro Schiavo

  • SNARE motif and neurotoxins

    Ornella Rossetto;Giampietro Schiavo;Cesare Montecucco;Bernard Poulain

  • SNAP-25 modulation of calcium dynamics underlies differences in GABAergic and glutamatergic responsiveness to depolarization

    Claudia Verderio;Davide Pozzi;Elena Pravettoni;Francesca Inverardi

  • Tetanus and botulinum neurotoxins: turning bad guys into good by research.

    Ornella Rossetto;Michela Seveso;Paola Caccin;Giampietro Schiavo

  • Functional characterisation of tetanus and botulinum neurotoxins binding domains.

    Giovanna Lalli;Judit Herreros;Shona L. Osborne;Cesare Montecucco

  • Different time courses of recovery after poisoning with botulinum neurotoxin serotypes A and E in humans

    Roberto Eleopra;Valeria Tugnoli;Ornella Rossetto;Domenico De Grandis

  • Equivalent Effects of Snake PLA2 Neurotoxins and Lysophospholipid-Fatty Acid Mixtures

    Michela Rigoni;Paola Caccin;Paola Caccin;Paola Caccin;Steve Gschmeissner;Steve Gschmeissner;Steve Gschmeissner;Grielof Koster;Grielof Koster;Grielof Koster

  • Botulinum Neurotoxins A and E Undergo Retrograde Axonal Transport in Primary Motor Neurons

    Laura Restani;Francesco Giribaldi;Maria Manich;Maria Manich;Kinga Bercsenyi

  • VAMP/synaptobrevin isoforms 1 and 2 are widely and differentially expressed in nonneuronal tissues.

    O Rossetto;L Gorza;G Schiavo;N Schiavo

Frequent Co-Authors

Cesare Montecucco
Cesare Montecucco University of Padua
Giampietro Schiavo
Giampietro Schiavo University College London
Thomas Binz
Thomas Binz Hanover University of Applied Sciences and Arts
Roberto Eleopra
Roberto Eleopra Misericordia University
Matteo Caleo
Matteo Caleo University of Padua
Claudia Verderio
Claudia Verderio University of Milan
Michela Matteoli
Michela Matteoli Humanitas University
Eric A. Johnson
Eric A. Johnson University of Wisconsin–Madison
Fabio Benfenati
Fabio Benfenati Italian Institute of Technology
Flaminia Pavone
Flaminia Pavone National Academies of Sciences, Engineering, and Medicine

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