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Microbiology

D-Index
65
Citations
11799
World Ranking
2553
National Ranking
1030

Overview

Joseph T. Barbieri is affiliated with the Medical College of Wisconsin in the United States. Their research primarily spans the field of Medicine, with a notable focus on Neurology, Cellular and Molecular Neuroscience, and Infectious Diseases. Within these areas, their work addresses a variety of specific topics including Botulinum Toxin and Related Neurological Disorders, Neurological Disorders and Treatments, Hereditary Neurological Disorders, and the study of pathogenic bacteria such as Clostridium difficile and Clostridium perfringens.

Barbieri has contributed publications to several scientific venues, with frequent appearances in the International Journal of Molecular Sciences and Toxicon, each hosting three of their publications. Additionally, their work has appeared in Vaccine, mBio, and Biochemistry.

Recent papers include:

  • A Novel High-Potency Tetanus Vaccine, 2020, mBio
  • Genetically detoxified tetanus toxin as a vaccine and conjugate carrier protein, 2022, Vaccine
  • Tetanus Toxin cis-Loop Contributes to Light-Chain Translocation, 2020, mSphere
  • Multiple Domains of Staphylococcal Superantigen-like Protein 11 (SSL11) Contribute to Neutrophil Inhibition, 2022, Biochemistry
  • How Botulinum Neurotoxin Light Chain A1 Maintains Stable Association with the Intracellular Neuronal Plasma Membrane, 2022, Toxins

Collaboration is a significant aspect of Barbieri's research activity. Frequent co-authors include Sabine Pellett, William H. Tepp, Amanda Przedpelski, Marite Bradshaw, and Alexander P. Gardner, reflecting ongoing partnerships in related fields of study.

The scientist's subfield expertise covers Neurology extensively with 22 publications, alongside engagements in Cellular and Molecular Neuroscience, Infectious Diseases, Molecular Biology, and Endocrinology. Their focus on neurological disorders particularly emphasizes biochemical and structural characterization relevant to toxins and hereditary conditions, as well as applied research in vaccine development and bacterial pathogenesis.

Best Publications

  • ExoY, an adenylate cyclase secreted by the Pseudomonas aeruginosa type III system.

    Timothy L. Yahr;Amy J. Vallis;Michael K. Hancock;Joseph T. Barbieri

  • Mutants of pertussis toxin suitable for vaccine development

    Mariagrazia Pizza;Antonio Covacci;Antonella Bartoloni;Maria Perugini

  • The N-terminal Domain of Pseudomonas aeruginosaExoenzyme S Is a GTPase-activating Protein for Rho GTPases

    Udo-Michael Goehring;Gudula Schmidt;Kristin J. Pederson;Klaus Aktories

  • Bacterial cytotoxins: targeting eukaryotic switches

    Klaus Aktories;Joseph T. Barbieri

  • Pseudomonas aeruginosa ExoS and ExoT.

    J. T. Barbieri;J. Sun

  • Novel bacterial ADP-ribosylating toxins: structure and function.

    Nathan C. Simon;Klaus Aktories;Joseph T. Barbieri

  • Bacterial toxins that modify the actin cytoskeleton.

    Joseph T. Barbieri;Matthew J. Riese;Klaus Aktories

  • Pseudomonas aeruginosa ExoT Is a Rho GTPase-Activating Protein

    Rebecca Krall;Gudula Schmidt;Klaus Aktories;Joseph T. Barbieri

  • The family of bacterial ADP-ribosylating exotoxins.

    K M Krueger;J T Barbieri

  • Molecular Mechanisms of the Cytotoxicity of ADP-Ribosylating Toxins

    Qing Deng;Joseph T. Barbieri

  • Interaction of 14-3-3 with a nonphosphorylated protein ligand, exoenzyme S of Pseudomonas aeruginosa.

    Shane C. Masters;Kristin J. Pederson;Lixin Zhang;Joseph T. Barbieri

  • Regulation of ExoS production and secretion by Pseudomonas aeruginosa in response to tissue culture conditions.

    Amy J. Vallis;Timothy L. Yahr;Joseph T. Barbieri;Dara W. Frank

  • Glycosylated SV2 and Gangliosides as Dual Receptors for Botulinum Neurotoxin Serotype F

    Zhuji Fu;Chen Chen;Joseph T. Barbieri;Jung-Ja P. Kim

  • The amino-terminal domain of Pseudomonas aeruginosa ExoS disrupts actin filaments via small-molecular-weight GTP-binding proteins.

    Kristin J. Pederson;Amy J. Vallis;Klaus Aktories;Dara W. Frank

  • Pseudomonas aeruginosa ExoT ADP-ribosylates CT10 regulator of kinase (Crk) proteins.

    Jianjun Sun;Joseph T. Barbieri

  • Gangliosides as High Affinity Receptors for Tetanus Neurotoxin

    Chen Chen;Zhuji Fu;Jung-Ja P. Kim;Joseph T. Barbieri

  • Genetic relationship between the 53- and 49-kilodalton forms of exoenzyme S from Pseudomonas aeruginosa.

    T L Yahr;J T Barbieri;D W Frank

  • Subunit vaccine against the seven serotypes of botulism.

    Michael R. Baldwin;William H. Tepp;Amanda Przedpelski;Christina L. Pier

  • Pseudomonas aeruginosa exoenzyme S ADP-ribosylates Ras at multiple sites.

    Anand K. Ganesan;Dara W. Frank;Ravi P. Misra;Gudula Schmidt

  • Diphtheria toxin. Effect of substituting aspartic acid for glutamic acid 148 on ADP-ribosyltransferase activity.

    R K Tweten;J T Barbieri;R J Collier

Frequent Co-Authors

Eric A. Johnson
Eric A. Johnson University of Wisconsin–Madison
Dara W. Frank
Dara W. Frank Medical College of Wisconsin
Sheng Chen
Sheng Chen University of Southampton
Jung-Ja P. Kim
Jung-Ja P. Kim Medical College of Wisconsin
Kim D. Janda
Kim D. Janda Scripps Research Institute
Robert J Collier
Robert J Collier University of Arizona
Klaus Aktories
Klaus Aktories University of Freiburg
Joel Moss
Joel Moss National Institutes of Health
David J. Evans
David J. Evans Touro University California
Timothy L. Yahr
Timothy L. Yahr University of Iowa

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