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D-Index & Metrics

Microbiology

D-Index
66
Citations
14189
World Ranking
2425
National Ranking
980

Overview

Dara W. Frank is affiliated with the Medical College of Wisconsin in the United States. Their research primarily focuses on the intersection of biochemistry, genetics, and molecular biology, with additional work in medicine.

Their main fields of study include:

  • Biochemistry, Genetics and Molecular Biology
  • Medicine

Their subfields of study cover:

  • Molecular Biology
  • Molecular Medicine
  • Endocrinology
  • Genetics
  • Pulmonary and Respiratory Medicine

Key topics addressed in their research comprise:

  • Antibiotic Resistance in Bacteria
  • Bacterial biofilms and quorum sensing
  • Bacterial Genetics and Biotechnology
  • Infections and bacterial resistance
  • Alzheimer's disease research and treatments
  • Sphingolipid Metabolism and Signaling
  • Electron Spin Resonance Studies

Their frequent collaborators include Troy Stevens, Molly O. Riegert, Ron Balczon, Maxx H. Tessmer, and S.B. Voth.

Dara W. Frank has contributed to multiple papers, some of the recent ones include:

  • Virulent Pseudomonas aeruginosa infection converts antimicrobial amyloids into cytotoxic prions, 2020, The FASEB Journal
  • Perspectives on the Pseudomonas aeruginosa Type III Secretion System Effector ExoU and Its Subversion of the Host Innate Immune Response to Infection, 2021, Toxins
  • Achromobacter xylosoxidans Cellular Pathology Is Correlated with Activation of a Type III Secretion System, 2020, Infection and Immunity
  • Host phospholipid peroxidation fuels ExoU-dependent cell necrosis and supports Pseudomonas aeruginosa-driven pathology, 2021, PLoS Pathogens
  • Exoenzyme Y induces extracellular active caspase-7 accumulation independent from apoptosis: modulation of transmissible cytotoxicity, 2020, American Journal of Physiology-Lung Cellular and Molecular Physiology

They have published frequently in several scientific venues including:

  • American Journal of Physiology-Lung Cellular and Molecular Physiology
  • The FASEB Journal
  • Infection and Immunity
  • Protein Science
  • Toxins

Best Publications

  • ExoU expression by Pseudomonas aeruginosa correlates with acute cytotoxicity and epithelial injury.

    Viviane Finck-Barbançon;Joanne Goranson;Lei Zhu;Teiji Sawa

  • Type III protein secretion is associated with death in lower respiratory and systemic Pseudomonas aeruginosa infections

    Arup Roy-Burman;Richard H. Savel;Sara Racine;Britta L. Swanson

  • ExoY, an adenylate cyclase secreted by the Pseudomonas aeruginosa type III system.

    Timothy L. Yahr;Amy J. Vallis;Michael K. Hancock;Joseph T. Barbieri

  • The exoenzyme S regulon of Pseudomonas aeruginosa.

    Dara W. Frank

  • The mechanism of action of the Pseudomonas aeruginosa‐encoded type III cytotoxin, ExoU

    Hiromi Sato;Dara W. Frank;Cecilia J. Hillard;Jimmy B. Feix

  • Pathogenesis of septic shock in Pseudomonas aeruginosa pneumonia

    Kiyoyasu Kurahashi;Osamu Kajikawa;Teiji Sawa;Maria Ohara

  • Active and passive immunization with the Pseudomonas V antigen protects against type III intoxication and lung injury.

    Teiji Sawa;Timothy L. Yahr;Maria Ohara;Kiyoyasu Kurahashi

  • Pseudomonas aeruginosa-mediated cytotoxicity and invasion correlate with distinct genotypes at the loci encoding exoenzyme S.

    S. M. J. Fleiszig;J. P. Wiener-Kronish;H. Miyazaki;V. Vallas

  • EXOENZYME S OF PSEUDOMONAS AERUGINOSA IS SECRETED BY A TYPE III PATHWAY

    Timothy L. Yahr;Joanne Goranson;Dara W. Frank

  • ExoU is a potent intracellular phospholipase.

    Hiromi Sato;Dara W. Frank

  • Use of the Galleria mellonella Caterpillar as a Model Host To Study the Role of the Type III Secretion System in Pseudomonas aeruginosa Pathogenesis

    Sachiko Miyata;Monika Casey;Dara W. Frank;Frederick M. Ausubel

  • Identification of type III secreted products of the Pseudomonas aeruginosa exoenzyme S regulon.

    Timothy L. Yahr;Liane M. Mende-Mueller;Matthew B. Friese;Dara W. Frank

  • Generation and Characterization of a Protective Monoclonal Antibody to Pseudomonas aeruginosa PcrV

    Dara W. Frank;Amy Vallis;Jeanine P. Wiener-Kronish;Arup Roy-Burman

  • Analyses of the DNA-binding and transcriptional activation properties of ExsA, the transcriptional activator of the Pseudomonas aeruginosa exoenzyme S regulon.

    A K Hovey;D W Frank

  • Regulation of ExoS production and secretion by Pseudomonas aeruginosa in response to tissue culture conditions.

    Amy J. Vallis;Timothy L. Yahr;Joseph T. Barbieri;Dara W. Frank

  • Construction and characterization of a highly efficient Francisella shuttle plasmid.

    Tamara M. Maier;Andrea Havig;Monika Casey;Francis E. Nano

  • The amino-terminal domain of Pseudomonas aeruginosa ExoS disrupts actin filaments via small-molecular-weight GTP-binding proteins.

    Kristin J. Pederson;Amy J. Vallis;Klaus Aktories;Dara W. Frank

  • Biological effects of Pseudomonas aeruginosa type III-secreted proteins on CHO cells.

    Amy J. Vallis;Viviane Finck-Barbançon;Timothy L. Yahr;Dara W. Frank

  • Paradoxical cAMP-Induced Lung Endothelial Hyperpermeability Revealed by Pseudomonas aeruginosa ExoY

    Sarah L. Sayner;Dara W. Frank;Judy King;Hairu Chen

  • Genetic relationship between the 53- and 49-kilodalton forms of exoenzyme S from Pseudomonas aeruginosa.

    T L Yahr;J T Barbieri;D W Frank

Frequent Co-Authors

Timothy L. Yahr
Timothy L. Yahr University of Iowa
Jeanine P. Wiener-Kronish
Jeanine P. Wiener-Kronish Harvard University
Joseph T. Barbieri
Joseph T. Barbieri Medical College of Wisconsin
Troy Stevens
Troy Stevens University of South Alabama
Barbara H. Iglewski
Barbara H. Iglewski University of Rochester
Roland Seifert
Roland Seifert Hannover Medical School
Suzanne M. J. Fleiszig
Suzanne M. J. Fleiszig University of California, Berkeley
Volkhard Kaever
Volkhard Kaever Hannover Medical School
Jens Meiler
Jens Meiler Vanderbilt University
Daniel Ladant
Daniel Ladant Institut Pasteur

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