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Microbiology

D-Index
60
Citations
13942
World Ranking
3112
National Ranking
1231

Overview

Alan R. Hauser is affiliated with Northwestern University in the United States. Their research spans multiple disciplines with a focus on biochemistry, genetics, molecular biology, and medicine. This includes extensive work in molecular biology, molecular medicine, epidemiology, infectious diseases, and pharmacology.

The scientist's research interests are primarily centered on topics such as:

  • Antibiotic Resistance in Bacteria
  • Bacterial biofilms and quorum sensing
  • Antibiotics Pharmacokinetics and Efficacy
  • Genomics and Phylogenetic Studies
  • Pneumonia and Respiratory Infections
  • Clostridium difficile and Clostridium perfringens research
  • Gut microbiota and health

Hauser has contributed to numerous scientific publications. Notable recent papers include:

  • Circuits between infected macrophages and T cells in SARS-CoV-2 pneumonia, 2021, published in Nature
  • Systemic infection facilitates transmission of Pseudomonas aeruginosa in mice, 2020, published in Nature Communications
  • A clade of SARS-CoV-2 viruses associated with lower viral loads in patient upper airways, 2020, published in EBioMedicine
  • A comparative genomics approach identifies contact-dependent growth inhibition as a virulence determinant, 2020, published in Proceedings of the National Academy of Sciences
  • Genomic surveillance for multidrug-resistant or hypervirulent Klebsiella pneumoniae among United States bloodstream isolates, 2022, published in BMC Infectious Diseases

Frequent collaborators in Hauser's work include Egon A. Ozer, Richard G. Wunderink, Sophia Nozick, Kelly E. R. Bachta, and Marine Lebrun-Corbin. Collaboration with these coauthors reflects a network of research activity across infectious diseases and molecular biology.

The scientist's work has appeared regularly in several publication venues, with significant contributions in:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Open Forum Infectious Diseases
  • Antimicrobial Agents and Chemotherapy
  • mBio
  • Microbiology Spectrum

Best Publications

  • The type III secretion system of Pseudomonas aeruginosa : infection by injection

    Alan R. Hauser

  • Circuits between infected macrophages and T cells in SARS-CoV-2 pneumonia.

    Rogan A Grant;Luisa Morales-Nebreda;Nikolay S Markov;Suchitra Swaminathan

  • Prevalence of type III secretion genes in clinical and environmental isolates of Pseudomonas aeruginosa.

    Heather Feltman;Grant Schulert;Salman Khan;Manu Jain

  • Clinical Significance of Microbial Infection and Adaptation in Cystic Fibrosis

    Alan R. Hauser;Manu Jain;Maskit Bar-Meir;Susanna A. McColley

  • Type III protein secretion is associated with poor clinical outcomes in patients with ventilator-associated pneumonia caused by Pseudomonas aeruginosa.

    Alan R. Hauser;Enesha Cobb;Maria Bodí;Dolors Mariscal

  • Streptococcus pyogenes causing toxic-shock-like syndrome and other invasive diseases: clonal diversity and pyrogenic exotoxin expression.

    James M. Musser;Alan R. Hauser;Michael H. Kim;Patrick M. Schlievert

  • Relative contributions of Pseudomonas aeruginosa ExoU, ExoS, and ExoT to virulence in the lung

    Ciara M. Shaver;Alan R. Hauser

  • Clonal basis for resurgence of serious Streptococcus pyogenes disease in the 1980s.

    P. P. Cleary;P. M. Schlievert;J. P. Handley;Michael H Kim

  • The biofilm life cycle and virulence of Pseudomonas aeruginosa are dependent on a filamentous prophage

    Scott A. Rice;Chuan Hao Tan;Chuan Hao Tan;Per Jensen Mikkelsen;Vanderlene Kung

  • The Accessory Genome of Pseudomonas aeruginosa

    Vanderlene L. Kung;Egon A. Ozer;Alan R. Hauser

  • Pseudomonas aeruginosa gene products PilT and PilU are required for cytotoxicity in vitro and virulence in a mouse model of acute pneumonia

    James C. Comolli;Alan R. Hauser;Leslie Waite;Cynthia B. Whitchurch

  • Molecular analysis of pyrogenic exotoxins from Streptococcus pyogenes isolates associated with toxic shock-like syndrome.

    A R Hauser;D L Stevens;E L Kaplan;P M Schlievert

  • Secretion of the Toxin ExoU Is a Marker for Highly Virulent Pseudomonas aeruginosa Isolates Obtained from Patients with Hospital-Acquired Pneumonia

    Grant S. Schulert;Heather Feltman;Shira D. P. Rabin;Ciara G. Martin

  • Pseudomonas aeruginosa virulence and therapy: evolving translational strategies.

    Jeffrey L. Veesenmeyer;Alan R. Hauser;Thiago Lisboa;Jordi Rello

  • Genome-Wide Identification of Acinetobacter baumannii Genes Necessary for Persistence in the Lung

    Nengding Wang;Egon A. Ozer;Mark J. Mandel;Alan R. Hauser

  • PepA, a secreted protein of Pseudomonas aeruginosa, is necessary for cytotoxicity and virulence.

    Alan R. Hauser;Pil Jung Kang;Joanne N. Engel

  • The Arginine Finger Domain of ExoT Contributes to Actin Cytoskeleton Disruption and Inhibition of Internalization of Pseudomonas aeruginosa by Epithelial Cells and Macrophages

    L. Garrity-Ryan;B. Kazmierczak;R. Kowal;J. Comolli

  • Characterization of the core and accessory genomes of Pseudomonas aeruginosa using bioinformatic tools Spine and AGEnt

    Egon A Ozer;Jonathan P Allen;Alan R Hauser

  • Pseudomonas aeruginosa Induces Type-III-Secretion-Mediated Apoptosis of Macrophages and Epithelial Cells

    Alan R. Hauser;Joanne N. Engel

  • Nucleotide sequence of the streptococcal pyrogenic exotoxin type B gene and relationship between the toxin and the streptococcal proteinase precursor.

    A R Hauser;P M Schlievert

  • Streptococcus pyogenes causing toxic-shock-like syndrome and other invasive diseases

    James M. Musser;Alan R. Hauser;Michael H Kim;Patrick M. Schlievert

Frequent Co-Authors

Jordi Rello
Jordi Rello Instituto de Salud Carlos III
Joanne N. Engel
Joanne N. Engel University of California, San Francisco
Cheng-Hsun Chiu
Cheng-Hsun Chiu Chang Gung University
Patrick M. Schlievert
Patrick M. Schlievert University of Iowa
Dale N. Gerding
Dale N. Gerding Veterans Health Administration
Antonio Oliver
Antonio Oliver Instituto de Salud Carlos III
Francisco M. Marty
Francisco M. Marty Brigham and Women's Hospital
John J. Mekalanos
John J. Mekalanos Harvard Medical School
Wayne F. Anderson
Wayne F. Anderson Northwestern University
Richard G. Wunderink
Richard G. Wunderink Northwestern University

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