World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
58
Citations
11578
World Ranking
13224
National Ranking
1034

Overview

Dominic J. Wells is affiliated with the Royal Veterinary College in the United Kingdom. Their research primarily focuses on areas within biochemistry, genetics, and molecular biology, with a total of 57 publications in these fields. Medicine is another significant area of study for Wells, with 28 associated publications.

Their work spans multiple subfields including molecular biology, surgery, biomedical engineering, physiology, and genetics. Molecular biology represents the most prominent subfield with 44 publications. Other subfields such as surgery and biomedical engineering each account for 9 articles, while physiology and genetics include 7 publications each.

The main topics addressed in Wells's research encompass muscle physiology and disorders, adipose tissue and metabolism, tissue engineering and regenerative medicine, RNA research and splicing, molecular biology techniques and applications, virus-based gene therapy research, and muscle metabolism and nutrition. Muscle physiology and disorders is the dominant research topic with 54 publications, followed by adipose tissue and metabolism and tissue engineering and regenerative medicine with 14 publications each.

Frequent co-authors collaborating with Wells include:

  • Richard J. Piercy
  • John Hildyard
  • Rachel Harron
  • Dominique Riddell
  • Annemieke Aartsma-Rus

Dominic J. Wells regularly publishes in several scientific venues. The most frequent publication outlets are:

  • Wellcome Open Research
  • Neuromuscular Disorders
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Disease Models & Mechanisms
  • Journal of Neuromuscular Diseases

Recent notable papers include:

  • Improving translatability of preclinical studies for neuromuscular disorders: lessons from the TREAT-NMD Advisory Committee for Therapeutics (TACT), 2020, Disease Models & Mechanisms
  • The skeletal muscle phenotype of the DE50-MD dog model of Duchenne muscular dystrophy, 2022, Wellcome Open Research
  • Musculoskeletal magnetic resonance imaging in the DE50-MD dog model of Duchenne muscular dystrophy, 2021, Neuromuscular Disorders
  • Validation of DE50-MD dogs as a model for the brain phenotype of Duchenne muscular dystrophy, 2022, Disease Models & Mechanisms
  • Simvastatin Treatment Does Not Ameliorate Muscle Pathophysiology in a Mouse Model for Duchenne Muscular Dystrophy, 2020, Journal of Neuromuscular Diseases

Best Publications

  • Exon skipping and dystrophin restoration in patients with Duchenne muscular dystrophy after systemic phosphorodiamidate morpholino oligomer treatment: an open-label, phase 2, dose-escalation study.

    Sebahattin Cirak;Virginia Arechavala-Gomeza;Michela Guglieri;Lucy Feng

  • Local restoration of dystrophin expression with the morpholino oligomer AVI-4658 in Duchenne muscular dystrophy: a single-blind, placebo-controlled, dose-escalation, proof-of-concept study

    Maria Kinali;Maria Kinali;Virginia Arechavala-Gomeza;Lucy Feng;Sebahattin Cirak

  • Gene Therapy Progress and Prospects: Electroporation and other physical methods

    D J Wells

  • Gene expression in skeletal muscle in response to stretch and force generation

    G. Goldspink;A. Scutt;P. T. Loughna;D. J. Wells

  • Optimisation of electrotransfer of plasmid into skeletal muscle by pretreatment with hyaluronidase -- increased expression with reduced muscle damage.

    JM McMahon;E Signori;KE Wells;VM Fazio;VM Fazio

  • Three-dimensional Human iPSC-derived Artificial Skeletal Muscles Model Muscular Dystrophies and Enable Multilineage Tissue Engineering

    Sara Martina Maffioletti;Shilpita Sarcar;Alexander B.H. Henderson;Ingra Mannhardt

  • Age-related changes in collagen gene expression in the muscles of mdx dystrophic and normal mice

    Geoffrey Goldspink;Kenneth Fernandes;Pamela E. Williams;Dominic J. Wells

  • The Neuroprotective Effects of Heat Shock Protein 27 Overexpression in Transgenic Animals against Kainate-induced Seizures and Hippocampal Cell Death

    Mohammed T. Akbar;Anna M.C. Lundberg;Ke Liu;Sharmili Vidyadaran

  • Expression of human full-length and minidystrophin in transgenic mdx mice: implications for gene therapy of Duchenne muscular dystrophy

    Dominic J. Wells;Kim E. Wells;Emmanuel A. Asante;Gaynor Turner

  • Improved Gene Transfer by Direct Plasmid Injection Associated With Regeneration in Mouse Skeletal Muscle

    Dominic J. Wells

  • Direct retroviral-mediated transfer of a dystrophin minigene into mdx mouse muscle in vivo

    Matthew G. Dunckley;Dominic J. Wells;Frank S. Walsh;George Dickson

  • Heat shock protein 27 protects the heart against myocardial infarction.

    Christopher A. Efthymiou;Mihaela M. Mocanu;Jackie de Belleroche;Dominic J. Wells

  • Extracellular Release of the Atheroprotective Heat Shock Protein 27 Is Mediated by Estrogen and Competitively Inhibits acLDL Binding to Scavenger Receptor-A

    Katey Rayner;Yong-Xiang Chen;Melissa McNulty;Trevor Simard

  • Running energetics in the pronghorn antelope

    Stan L. Lindstedt;Stan L. Lindstedt;James F. Hokanson;James F. Hokanson;Dominic J. Wells;Dominic J. Wells;Steven D. Swain

  • Adeno-associated virus vector gene transfer and sarcolemmal expression of a 144 kDa micro-dystrophin effectively restores the dystrophin-associated protein complex and inhibits myofibre degeneration in nude/mdx mice

    Stewart A. Fabb;Dominic J. Wells;Patricia Serpente;George Dickson

  • Electroporation for gene transfer to skeletal muscles: current status.

    Jillian M McMahon;Dominic J Wells

  • How much dystrophin is enough: the physiological consequences of different levels of dystrophin in the mdx mouse

    C Godfrey;S Muses;G McClorey;K E Wells

  • Codon and mRNA Sequence Optimization of Microdystrophin Transgenes Improves Expression and Physiological Outcome in Dystrophic mdx Mice Following AAV2/8 Gene Transfer

    Helen Foster;Paul S Sharp;Takis Athanasopoulos;Capucine Trollet

  • Protective effects of heat shock protein 27 in a model of ALS occur in the early stages of disease progression.

    Paul S. Sharp;Mohammed T. Akbar;Sonia Bouri;Atsushi Senda

  • Zebrafish melanopsin: isolation, tissue localisation and phylogenetic position

    James Bellingham;David Whitmore;Alisdair R Philp;Dominic J Wells

Frequent Co-Authors

George Dickson
George Dickson Royal Holloway University of London
Francesco Muntoni
Francesco Muntoni University College London
Jennifer E. Morgan
Jennifer E. Morgan University College London
Volker Straub
Volker Straub Newcastle University
Frank S. Walsh
Frank S. Walsh Wolfson Centre for Age-Related Diseases
Annemieke Aartsma-Rus
Annemieke Aartsma-Rus Leiden University Medical Center
Matthew J.A. Wood
Matthew J.A. Wood University of Oxford
Steven B. Marston
Steven B. Marston National Institutes of Health
Kieran Clarke
Kieran Clarke University of Oxford
John R. Hutchinson
John R. Hutchinson Royal Veterinary College

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Best Scientists Citing Dominic J. Wells

Trending Scientists

Recently Published Articles