What is he best known for?
The fields of study he is best known for:
- Gene
- Internal medicine
- DNA
Dominic J. Wells spends much of his time researching Molecular biology, Dystrophin, Duchenne muscular dystrophy, Muscular dystrophy and Skeletal muscle.
The various areas that Dominic J. Wells examines in his Molecular biology study include Plasmid, Transgene, Viral vector, Genetic enhancement and Electroporation.
His Dystrophin research includes themes of Exon skipping, Eteplirsen, Drisapersen and Morpholino.
His research integrates issues of Pathology and Exon in his study of Muscular dystrophy.
His Skeletal muscle research is multidisciplinary, incorporating perspectives in Gene expression and Cell biology.
His Internal medicine research includes elements of Regulation of gene expression and MYH7.
His most cited work include:
- Exon skipping and dystrophin restoration in patients with Duchenne muscular dystrophy after systemic phosphorodiamidate morpholino oligomer treatment: an open-label, phase 2, dose-escalation study. (690 citations)
- Local restoration of dystrophin expression with the morpholino oligomer AVI-4658 in Duchenne muscular dystrophy: a single-blind, placebo-controlled, dose-escalation, proof-of-concept study (569 citations)
- Gene Therapy Progress and Prospects: Electroporation and other physical methods (308 citations)
What are the main themes of his work throughout his whole career to date?
Duchenne muscular dystrophy, Dystrophin, Molecular biology, Cell biology and Skeletal muscle are his primary areas of study.
His study looks at the intersection of Duchenne muscular dystrophy and topics like Endocrinology with Hsp27.
His work carried out in the field of Dystrophin brings together such families of science as Exon skipping and Morpholino.
His studies in Molecular biology integrate themes in fields like Plasmid, Gene expression, Transgene, Transfection and Genetic enhancement.
His study in Cell biology is interdisciplinary in nature, drawing from both Vector, Cardiac muscle and Transplantation.
His studies deal with areas such as Myocyte and In vivo as well as Skeletal muscle.
He most often published in these fields:
- Duchenne muscular dystrophy (29.72%)
- Dystrophin (27.83%)
- Molecular biology (27.36%)
What were the highlights of his more recent work (between 2013-2021)?
- Duchenne muscular dystrophy (29.72%)
- Dystrophin (27.83%)
- Skeletal muscle (19.81%)
In recent papers he was focusing on the following fields of study:
Dominic J. Wells focuses on Duchenne muscular dystrophy, Dystrophin, Skeletal muscle, Muscular dystrophy and Internal medicine.
His work on mdx mouse as part of general Duchenne muscular dystrophy research is often related to 6-minute walk test, thus linking different fields of science.
His Dystrophin study integrates concerns from other disciplines, such as Fibrosis, Exon skipping, Muscle contraction and Cell biology.
He combines topics linked to Pathology with his work on Skeletal muscle.
The study incorporates disciplines such as Muscle tissue, Transgene and Immunology in addition to Muscular dystrophy.
His Internal medicine research incorporates elements of Endocrinology and Cardiology.
Between 2013 and 2021, his most popular works were:
- Three-dimensional Human iPSC-derived Artificial Skeletal Muscles Model Muscular Dystrophies and Enable Multilineage Tissue Engineering (96 citations)
- How much dystrophin is enough: the physiological consequences of different levels of dystrophin in the mdx mouse (65 citations)
- Musculoskeletal Geometry, Muscle Architecture and Functional Specialisations of the Mouse Hindlimb. (53 citations)
In his most recent research, the most cited papers focused on:
- Gene
- Internal medicine
- DNA
His primary areas of study are Duchenne muscular dystrophy, Skeletal muscle, Cell biology, Anatomy and Bioinformatics.
His mdx mouse and Dystrophin study, which is part of a larger body of work in Duchenne muscular dystrophy, is frequently linked to Clinical neurology, bridging the gap between disciplines.
His mdx mouse study combines topics from a wide range of disciplines, such as Regulation of gene expression and Utrophin.
His Myogenic differentiation study in the realm of Skeletal muscle connects with subjects such as Induced pluripotent stem cell.
His research investigates the connection between Cell biology and topics such as Muscular dystrophy that intersect with issues in Cancer research, Transgene, Phenotype, Immunology and Cre recombinase.
His biological study spans a wide range of topics, including Endocrinology and Internal medicine.
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