D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Molecular Biology D-index 76 Citations 19,087 213 World Ranking 710 National Ranking 56

Research.com Recognitions

Awards & Achievements

Member of the European Molecular Biology Organization (EMBO)

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • DNA
  • Enzyme

His main research concerns Oligonucleotide, Biochemistry, Molecular biology, RNA and Peptide. His Oligonucleotide research is multidisciplinary, incorporating perspectives in Combinatorial chemistry, Cell and Peptide nucleic acid, Nucleic acid. His research in Biochemistry tackles topics such as In vivo which are related to areas like Oligomer, RNase P and RNA Stability.

He interconnects mdx mouse, Messenger RNA, Transcription and Luciferase in the investigation of issues within Molecular biology. His RNA research integrates issues from Base pair and Binding site. Michael J. Gait interconnects HeLa, Peptide sequence, RNA splicing and Transfection in the investigation of issues within Peptide.

His most cited work include:

  • Cell penetrating peptides (1506 citations)
  • Nucleotide sequence of tobacco mosaic virus RNA (566 citations)
  • Phosphoramidite derivatives, their preparation and the use thereof in the incorporation of reporter groups on synthetic oligonucleotides (485 citations)

What are the main themes of his work throughout his whole career to date?

Michael J. Gait mostly deals with Oligonucleotide, Biochemistry, RNA, Peptide and Molecular biology. The Oligonucleotide study combines topics in areas such as Combinatorial chemistry, Nucleic acid and Stereochemistry. As part of his studies on Biochemistry, he often connects relevant areas like In vivo.

As a member of one scientific family, he mostly works in the field of RNA, focusing on Binding site and, on occasion, Base pair. The study incorporates disciplines such as Peptide sequence, RNA splicing and Transfection in addition to Peptide. His Molecular biology study also includes fields such as

  • Duchenne muscular dystrophy which connect with Morpholino,
  • Cell biology most often made with reference to Dystrophin.

He most often published in these fields:

  • Oligonucleotide (52.19%)
  • Biochemistry (34.26%)
  • RNA (27.49%)

What were the highlights of his more recent work (between 2010-2019)?

  • Oligonucleotide (52.19%)
  • Duchenne muscular dystrophy (10.36%)
  • Exon skipping (9.16%)

In recent papers he was focusing on the following fields of study:

The scientist’s investigation covers issues in Oligonucleotide, Duchenne muscular dystrophy, Exon skipping, Molecular biology and Nucleic acid. His study with Oligonucleotide involves better knowledge in Biochemistry. His work in the fields of Dystrophin overlaps with other areas such as Identification.

His Nucleic acid research includes themes of Combinatorial chemistry, Locked nucleic acid, Stereochemistry and Cell-penetrating peptide. His Peptide research is multidisciplinary, incorporating perspectives in Biomolecule, Peptide sequence and Cysteine. His RNA study incorporates themes from Duplex and Computational biology.

Between 2010 and 2019, his most popular works were:

  • Delivery of therapeutic oligonucleotides with cell penetrating peptides (142 citations)
  • Pip6-PMO, A New Generation of Peptide-oligonucleotide Conjugates With Improved Cardiac Exon Skipping Activity for DMD Treatment (133 citations)
  • Pip5 Transduction Peptides Direct High Efficiency Oligonucleotide-mediated Dystrophin Exon Skipping in Heart and Phenotypic Correction in mdx Mice (104 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • DNA
  • Enzyme

His primary areas of investigation include Oligonucleotide, Duchenne muscular dystrophy, Molecular biology, Dystrophin and Exon skipping. His Oligonucleotide study combines topics in areas such as Cell, Nucleic acid and Peptide. As part of the same scientific family, he usually focuses on Nucleic acid, concentrating on Computational biology and intersecting with RNA, Anti-miRNA oligonucleotides, RNA extraction, Locked nucleic acid and Blot.

His Molecular biology research incorporates themes from Cancer research and Exon. His study focuses on the intersection of Dystrophin and fields such as Cell biology with connections in the field of Skeletal muscle and Cardiac muscle. His research investigates the link between Biochemistry and topics such as Biophysics that cross with problems in Micelle, DNA, Receptor-mediated endocytosis, Cell culture and Biomolecule.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Cell penetrating peptides

Michael John Gait;Andrey Alexandrovich Arzumanov;Gabriela Dimitroval Ivanova.
Journal of Biological Chemistry (2009)

2499 Citations

Nucleotide sequence of tobacco mosaic virus RNA

P. Goelet;G. P. Lomonossoff;P. J. G. Butler;M. E. Akam.
Proceedings of the National Academy of Sciences of the United States of America (1982)

875 Citations

Phosphoramidite derivatives, their preparation and the use thereof in the incorporation of reporter groups on synthetic oligonucleotides

Konrad Misiura;Michael J. Gait.
(1991)

764 Citations

Human immunodeficiency virus 1 tat protein binds trans-activation-responsive region (TAR) RNA in vitro

Colin Dingwall;Ingemar Ernberg;Michael J. Gait;Sheila M. Green.
Proceedings of the National Academy of Sciences of the United States of America (1989)

678 Citations

HIV-1 tat protein stimulates transcription by binding to a U-rich bulge in the stem of the TAR RNA structure.

Colin Dingwall;Ingemar Ernberg;Michael J. Gait;Sheila M. Green.
The EMBO Journal (1990)

524 Citations

miR-122 targeting with LNA/2′-O-methyl oligonucleotide mixmers, peptide nucleic acids (PNA), and PNA–peptide conjugates

Martin M. Fabani;Michael J. Gait.
RNA (2008)

390 Citations

Configurationally defined phosphorothioate-containing oligoribonucleotides in the study of the mechanism of cleavage of hammerhead ribozymes

George Slim;Michael J. Gait.
Nucleic Acids Research (1991)

360 Citations

High affinity binding of TAR RNA by the human immunodeficiency virus type-1 tat protein requires base-pairs in the RNA stem and amino acid residues flanking the basic region.

Mark J. Churcher;Christina Lamont;François Hamy;Colin Dingwall.
Journal of Molecular Biology (1993)

354 Citations

Cell-penetrating peptide conjugates of peptide nucleic acids (PNA) as inhibitors of HIV-1 Tat-dependent trans -activation in cells

John J D Turner;Gabriela D. Ivanova;Birgit Verbeure;Donna Williams.
Nucleic Acids Research (2005)

321 Citations

Efficient methods for attaching non-radioactive labels to the 5' ends of synthetic oligodeoxyribonucleotides.

Sudhir Agrawal;Chris Christodoulou;Michael J. Gait.
Nucleic Acids Research (1986)

313 Citations

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