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Biology and Biochemistry

D-Index
64
Citations
21325
World Ranking
9475
National Ranking
335

Overview

Bernard Lebleu is affiliated with the University of Montpellier in France. Their research spans the intersection of biochemistry, genetics, molecular biology, and medicine, with a specific focus on molecular biology and pathology-related fields.

The scientist's work has contributed to several subfields including:

  • Molecular Biology
  • Pathology and Forensic Medicine
  • Developmental Neuroscience
  • Cardiology and Cardiovascular Medicine
  • Radiology, Nuclear Medicine and Imaging

Bernard Lebleu has published research broadly on core topics such as:

  • Cardiac Ischemia and Reperfusion
  • RNA Interference and Gene Delivery
  • Anesthesia and Neurotoxicity Research
  • Cardiac Fibrosis and Remodeling
  • Advanced biosensing and bioanalysis techniques
  • Cell death mechanisms and regulation
  • Chemical Synthesis and Analysis

Their recent papers include:

  • Feature Collection in Peptide Therapeutics: Current Applications and Future Directions (2024), published in Biomedicines
  • Oligonucleotides-Based Therapeutics (2021), published in Biomedicines
  • Anti-apoptotic peptide for long term cardioprotection in a mouse model of myocardial ischemia-reperfusion injury (2020), published in Scientific Reports
  • Cardioprotective effect of the TD anti-apoptotic peptide: Study of the mechanisms of action (2020), published in Archives of Cardiovascular Diseases Supplements
  • TD peptide as an adjunct of reperfusion therapy provides long-term cardioprotective effects in a mouse model of ischemia-reperfusion (2021), published in Archives of Cardiovascular Diseases Supplements

Frequent co-authors collaborating on these projects include:

  • Prisca Boisguérin
  • Aurélie Covinhes
  • Laura Gallot
  • Christian Barrère
  • Anne Vincent

Bernard Lebleu's research has been disseminated particularly in the following venues:

  • Biomedicines
  • Archives of Cardiovascular Diseases Supplements
  • Scientific Reports
  • Molecular Therapy - Nucleic Acids

Best Publications

  • A truncated HIV-1 Tat protein basic domain rapidly translocates through the plasma membrane and accumulates in the cell nucleus

    Eric Vivès;Priscille Brodin;Bernard Lebleu

  • Tat peptide-mediated cellular delivery: back to basics.

    Hilary Brooks;Bernard Lebleu;Eric Vivès

  • Oligonucleotides with modified phosphate and modified carbohydrate moieties at the respective chain termini

    Bernard Lebleu;Bernard Bayard

  • Cellular Uptake of Unconjugated TAT Peptide Involves Clathrin-dependent Endocytosis and Heparan Sulfate Receptors

    Jean Philippe Richard;Kamran Melikov;Hilary Brooks;Paul Prevot

  • Specific antiviral activity of a poly(L-lysine)-conjugated oligodeoxyribonucleotide sequence complementary to vesicular stomatitis virus N protein mRNA initiation site.

    Marc Lemaitre;Bernard Bayard;Bernard Lebleu

  • Intracellular distribution of microinjected antisense oligonucleotides.

    Jean Paul Leonetti;Nadir Mechti;Genevieve Degols;Corinne Gagnor

  • Interferon, double-stranded RNA, and protein phosphorylation

    B. Lebleu;Ganes Sen;S. Shaila;B. Cabrer

  • Different mechanisms for cellular internalization of the HIV-1 Tat-derived cell penetrating peptide and recombinant proteins fused to Tat.

    Michelle Silhol;Mudit Tyagi;Mauro Giacca;Bernard Lebleu

  • Design of a peptide-based vector, PepFect6, for efficient delivery of siRNA in cell culture and systemically in vivo.

    Samir E L Andaloussi;Taavi Lehto;Imre Mäger;Katri Rosenthal-Aizman

  • Cell-penetrating peptide conjugates of peptide nucleic acids (PNA) as inhibitors of HIV-1 Tat-dependent trans -activation in cells

    John J D Turner;Gabriela D. Ivanova;Birgit Verbeure;Donna Williams

  • Vectorization of morpholino oligomers by the (R-Ahx-R)4 peptide allows efficient splicing correction in the absence of endosomolytic agents.

    Saïd Abes;Hong M. Moulton;Philippe Clair;Paul Prevot

  • Delivery of therapeutic oligonucleotides with cell penetrating peptides

    Prisca Boisguérin;Sébastien Deshayes;Michael J. Gait;Liz O'Donovan

  • Increased rate of degradation of c-myc mRNA in interferon-treated Daudi cells

    C. Dani;Nadir Mechti;M. Piechaczyk;B. Lebleu

  • Biological activity of oligonucleotide-poly(L-lysine) conjugates: mechanism of cell uptake.

    Jean Paul Leonetti;Genevieve Degols;Bernard Lebleu

  • Improved cell-penetrating peptide–PNA conjugates for splicing redirection in HeLa cells and exon skipping in mdx mouse muscle

    Gabriela D. Ivanova;Andrey Arzumanov;Rachida Abes;Haifang Yin

  • Antibody-targeted liposomes containing oligodeoxyribonucleotides complementary to viral RNA selectively inhibit viral replication.

    Jean-Paul Leonetti;Patrick Machy;Genevieve Degols;Bernard Lebleu

  • Role of the Polyadenylate Segment in the Translation of Globin Messenger RNA in Xenopus Oocytes

    G. Huez;G. Marbaix;E. Hubert;M. Leclercq

  • Cell penetrating peptide conjugates of steric block oligonucleotides

    Bernard Lebleu;Hong M. Moulton;Rachida Abes;Gabriela D. Ivanova

  • Characterization of the Messenger Ribonucleoprotein Released from Reticulocyte Polyribosomes by EDTA Treatment

    Bernard Lebleu;Gérard Marbaix;Georges Huez;Jacques Temmerman

  • RNase L Inhibitor Is Induced during Human Immunodeficiency Virus Type 1 Infection and Down Regulates the 2-5A/RNase L Pathway in Human T Cells

    Camille Martinand;Céline Montavon;Tamim Salehzada;Michelle Silhol

Frequent Co-Authors

Uri Nudel
Uri Nudel Weizmann Institute of Science
Arsène Burny
Arsène Burny Université Libre de Bruxelles
Peter Lengyel
Peter Lengyel Yale University
Marc Piechaczyk
Marc Piechaczyk Centre national de la recherche scientifique, CNRS
Michael J. Gait
Michael J. Gait MRC Laboratory of Molecular Biology
Michel Revel
Michel Revel Weizmann Institute of Science
Samir El Andaloussi
Samir El Andaloussi Karolinska Institute
Christian Devaux
Christian Devaux Centre national de la recherche scientifique, CNRS
Hermona Soreq
Hermona Soreq Hebrew University of Jerusalem
Ülo Langel
Ülo Langel Stockholm University

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