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Biology and Biochemistry

D-Index
78
Citations
33493
World Ranking
4447
National Ranking
2161

Overview

Steven F. Dowdy is a researcher affiliated with the University of California, San Diego in the United States. Their work spans multiple areas within the fields of biochemistry, genetics, and molecular biology, with a particular focus on molecular biology and related subfields.

The scientist's research primarily covers topics including:

  • RNA Interference and Gene Delivery
  • Advanced biosensing and bioanalysis techniques
  • CRISPR and Genetic Engineering
  • Cancer-related Molecular Pathways
  • Nerve injury and regeneration
  • Pluripotent Stem Cells Research
  • Calcium signaling and nucleotide metabolism

Dowdy has contributed to the academic community through publications in diverse prominent venues. Frequent publication outlets include:

  • Nature
  • bioRxiv (Cold Spring Harbor Laboratory)
  • The FASEB Journal
  • Scientific Reports
  • Molecular Therapy - Nucleic Acids

Examples of recent papers authored or co-authored by Dowdy are:

  • "Delivery of RNA Therapeutics: The Great Endosomal Escape!", 2022, Nucleic Acid Therapeutics
  • "Endosomal escape of RNA therapeutics: How do we solve this rate-limiting problem?", 2023, RNA
  • "Reversing a model of Parkinson's disease with in situ converted nigral neurons", 2020, Nature
  • "Two-pore channels regulate Tat endolysosome escape and Tat-mediated HIV-1 LTR transactivation", 2020, The FASEB Journal
  • "Overcoming delivery barriers with LNPs", 2021, Nature Materials

Steven F. Dowdy frequently collaborates with several researchers, including:

  • William C. Mobley
  • Hao Qian
  • Yuanchao Xue
  • Xiang-Dong Fu
  • Satish Jadhav

Their primary research fields, supported by the volume of publications, include biochemistry, genetics, and molecular biology with a notable emphasis on molecular biology, as well as medicine. Within these broader areas, subfields such as cellular and molecular neuroscience, oncology, genetics, and physiology have been explored.

Best Publications

  • In Vivo Protein Transduction: Delivery of a Biologically Active Protein into the Mouse

    Steven R. Schwarze;Alan Ho;Adamina Vocero-Akbani;Steven F. Dowdy

  • Transducible TAT-HA fusogenic peptide enhances escape of TAT-fusion proteins after lipid raft macropinocytosis.

    Jehangir S Wadia;Radu V Stan;Steven F Dowdy

  • Transduction of full-length TAT fusion proteins into mammalian cells:TAT-p27Kip1 induces cell migration

    Hikaru Nagahara;Adamina M. Vocero-Akbani;Eric L. Snyder;Alan Ho

  • CDK inhibitors: cell cycle regulators and beyond.

    Arnaud Besson;Steven F. Dowdy;James M. Roberts

  • Overcoming cellular barriers for RNA therapeutics

    Steven F Dowdy

  • Physical interaction of the retinoblastoma protein with human D cyclins

    Steven F. Dowdy;Philip W. Hinds;Kenway Louie;Steven I. Reed

  • Protein transduction: unrestricted delivery into all cells?

    Steven R. Schwarze;Keith A. Hruska;Steven F. Dowdy

  • Cationic TAT peptide transduction domain enters cells by macropinocytosis.

    Ian M. Kaplan;Jehangir S. Wadia;Steven F. Dowdy

  • In vivo protein transduction: intracellular delivery of biologically active proteins, compounds and DNA.

    Steven R Schwarze;Steven F Dowdy

  • Protein transduction technology.

    Jehangir S Wadia;Steven F Dowdy

  • Function of a human cyclin gene as an oncogene.

    Philip W. Hinds;Steven F. Dowdy;Elinor Ng Eaton;Andrew Arnold

  • TAT-mediated protein transduction into mammalian cells.

    Michelle Becker-Hapak;Sandra S. McAllister;Steven F. Dowdy

  • Synthetic Protein Transduction Domains: Enhanced Transduction Potential in Vitro and in Vivo

    Alan Ho;Steven R. Schwarze;Sarah J. Mermelstein;Gabriel Waksman

  • GalNAc-siRNA Conjugates: Leading the Way for Delivery of RNAi Therapeutics

    Aaron D. Springer;Steven F. Dowdy

  • Highly cited research articles in Journal of Controlled Release: Commentaries and perspectives by authors

    Nicholas A. Peppas;Ruth Duncan;Gary E. Wnek;Allan S. Hoffman

  • Transmembrane delivery of protein and peptide drugs by TAT-mediated transduction in the treatment of cancer.

    Jehangir S Wadia;Steven F Dowdy

  • Cyclin D1 stimulation of estrogen receptor transcriptional activity independent of cdk4.

    Elizabeth Neuman;Mohamed H. Ladha;Nancy Lin;Todd M. Upton

  • Efficient siRNA delivery into primary cells by a peptide transduction domain-dsRNA binding domain fusion protein.

    Akiko Eguchi;Bryan R Meade;Bryan R Meade;Yung-Chi Chang;Craig T Fredrickson

  • Cell penetrating peptides in drug delivery.

    Eric L. Snyder;Steven F. Dowdy

  • A common E2F-1 and p73 pathway mediates cell death induced by TCR activation

    Natalie A. Lissy;Penny K. Davis;Meredith Irwin;William G. Kaelin

Frequent Co-Authors

Eric J. Stanbridge
Eric J. Stanbridge University of California, Irvine
Philip W. Hinds
Philip W. Hinds Tufts University
Keith A. Hruska
Keith A. Hruska Washington University in St. Louis
Bernard E. Weissman
Bernard E. Weissman University of North Carolina at Chapel Hill
Don W. Cleveland
Don W. Cleveland University of California, San Diego
John D. Crispino
John D. Crispino Northwestern University
Amittha Wickrema
Amittha Wickrema University of Chicago
Martin Lotz
Martin Lotz Scripps Research Institute
David Gius
David Gius Northwestern University

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