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Kazuhito Tomizawa

Kazuhito Tomizawa

D-Index & Metrics

Biology and Biochemistry

D-Index
60
Citations
13115
World Ranking
11937
National Ranking
818

Overview

Kazuhito Tomizawa is affiliated with Kumamoto University in Japan and has a research focus primarily in the fields of Biochemistry, Genetics, and Molecular Biology, with an emphasis on Molecular Biology. Their work spans multiple related subfields including Infectious Diseases, Physiology, Genetics, and Plant Science.

Their research topics cover various aspects of RNA biology and related molecular mechanisms. Key topics include:

  • RNA modifications and cancer
  • RNA and protein synthesis mechanisms
  • RNA Research and Splicing
  • Mitochondrial Function and Pathology
  • RNA regulation and disease
  • SARS-CoV-2 and COVID-19 Research
  • SARS-CoV-2 detection and testing

Tomizawa's recent papers illustrate the depth and focus of their research in RNA-related molecular biology and disease mechanisms. Selected publications are:

  • "Human transfer RNA modopathies: diseases caused by aberrations in transfer RNA modifications," 2021, FEBS Journal
  • "FTO Demethylates Cyclin D1 mRNA and Controls Cell-Cycle Progression," 2020, Cell Reports
  • "Loss of Ftsj1 perturbs codon-specific translation efficiency in the brain and is associated with X-linked intellectual disability," 2021, Science Advances
  • "N6-methyladenosine (m6A) is an endogenous A3 adenosine receptor ligand," 2021, Molecular Cell
  • "DDX41 coordinates RNA splicing and transcriptional elongation to prevent DNA replication stress in hematopoietic cells," 2022, Leukemia

The venues where Tomizawa frequently publishes include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Communications Biology
  • Nucleic Acids Research
  • Science Advances
  • Molecular Cell

Collaborative efforts are a significant part of their research activities. Frequent co-authors of Tomizawa include:

  • Fan-Yan Wei
  • Takeshi Chujo
  • Taku Kaitsuka
  • Tsutomu Suzuki
  • Yu Nagayoshi

Best Publications

  • Cysteinyl-tRNA synthetase governs cysteine polysulfidation and mitochondrial bioenergetics

    Takaaki Akaike;Tomoaki Ida;Fan-Yan Wei;Motohiro Nishida;Motohiro Nishida

  • CaM kinase Iα–induced phosphorylation of Drp1 regulates mitochondrial morphology

    Xiao Jian Han;Yun Fei Lu;Shun Ai Li;Taku Kaitsuka

  • Oxytocin improves long-lasting spatial memory during motherhood through MAP kinase cascade

    Kazuhito Tomizawa;Norichika Iga;Yun Fei Lu;Akiyoshi Moriwaki

  • Spinophilin regulates the formation and function of dendritic spines

    Jian Feng;Zhen Yan;Adriana B Ferreira;Kazuhito Tomizawa

  • An Isoform of the Neuronal Cyclin-dependent Kinase 5 (Cdk5) Activator

    Damu Tang;Jeffery Yeung;Ki-Young Lee;Masayuki Matsushita

  • A new cell-permeable peptide allows successful allogeneic islet transplantation in mice

    Hirofumi Noguchi;Masayuki Matsushita;Teru Okitsu;Teru Okitsu;Akiyoshi Moriwaki

  • Tau protein kinase I converts normal tau protein into A68-like component of paired helical filaments.

    K Ishiguro;M Takamatsu;K Tomizawa;A Omori

  • Protein phosphatase 1 modulation of neostriatal AMPA channels: regulation by DARPP-32 and spinophilin.

    Zhen Yan;Linda Hsieh-Wilson;Jian Feng;Kazuhito Tomizawa

  • Ciliary transition zone activation of phosphorylated Tctex-1 controls ciliary resorption, S-phase entry and fate of neural progenitors.

    Aiqun Li;Masaki Saito;Masaki Saito;Jen Zen Chuang;Yun Yu Tseng

  • Critical Role of Calpain-mediated Cleavage of Calcineurin in Excitotoxic Neurodegeneration

    Hai Yan Wu;Kazuhito Tomizawa;Yoshiya Oda;Fan Yan Wei

  • Cdk5/p35 regulates neurotransmitter release through phosphorylation and downregulation of P/Q-type voltage-dependent calcium channel activity.

    Kazuhito Tomizawa;Jun Ohta;Masayuki Matsushita;Akiyoshi Moriwaki

  • A High-Efficiency Protein Transduction System Demonstrating the Role of PKA in Long-Lasting Long-Term Potentiation

    Masayuki Matsushita;Kazuhito Tomizawa;Akiyoshi Moriwaki;Sheng Tian Li

  • Deficit of tRNALys modification by Cdkal1 causes the development of type 2 diabetes in mice

    Fan Yan Wei;Takeo Suzuki;Sayaka Watanabe;Satoshi Kimura

  • Cdk5-dependent regulation of glucose-stimulated insulin secretion

    Fan Yan Wei;Kazuaki Nagashima;Toshio Ohshima;Yasunori Saheki

  • Channel Function Is Dissociated from the Intrinsic Kinase Activity and Autophosphorylation of TRPM7/ChaK1

    Masayuki Matsushita;J. Ashot Kozak;Yoshio Shimizu;Derek T. McLachlin

  • Cophosphorylation of amphiphysin I and dynamin I by Cdk5 regulates clathrin-mediated endocytosis of synaptic vesicles.

    Kazuhito Tomizawa;Satoshi Sunada;Yun Fei Lu;Yoshiya Oda

  • SIRT7 controls hepatic lipid metabolism by regulating the ubiquitin-proteasome pathway

    Tatsuya Yoshizawa;Md. Fazlul Karim;Yoshifumi Sato;Takafumi Senokuchi

  • Truncation and Activation of Calcineurin A by Calpain I in Alzheimer Disease Brain

    Fei Liu;Inge Grundke-Iqbal;Khalid Iqbal;Yoshiya Oda

  • The NH2 terminus of influenza virus hemagglutinin-2 subunit peptides enhances the antitumor potency of polyarginine-mediated p53 protein transduction.

    Hiroyuki Michiue;Kazuhito Tomizawa;Fan Yan Wei;Masayuki Matsushita

  • Enhanced intracellular delivery using arginine-rich peptides by the addition of penetration accelerating sequences (Pas).

    Kentaro Takayama;Ikuhiko Nakase;Hiroyuki Michiue;Toshihide Takeuchi

Frequent Co-Authors

Kohji Takei
Kohji Takei Okayama University
Tsutomu Suzuki
Tsutomu Suzuki University of Tokyo
Hiroshi Yamada
Hiroshi Yamada Okayama University
Takaaki Akaike
Takaaki Akaike Tohoku University
Yoshiya Oda
Yoshiya Oda Eisai (Japan)
Katsuhiko Mikoshiba
Katsuhiko Mikoshiba ShanghaiTech University
Toshio Ohshima
Toshio Ohshima Waseda University
Asuka Inoue
Asuka Inoue Tohoku University
Yuichi Oike
Yuichi Oike Kumamoto University
Masaharu Seno
Masaharu Seno Okayama University

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