World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
45
Citations
14071
World Ranking
19040
National Ranking
7772

Overview

Yisang Yoon is affiliated with Augusta University in the United States. Their research primarily focuses on biochemistry, genetics, and molecular biology, with significant contributions to medicine. Their work spans multiple subfields, including molecular biology, physiology, ophthalmology, clinical biochemistry, and general biochemistry.

Their research covers several key scientific topics such as mitochondrial function and pathology, metabolism and genetic disorders, ophthalmology and visual impairment studies, ATP synthase and ATPases research, nitric oxide and endothelin effects, neutrophil, myeloperoxidase and oxidative mechanisms, and ferroptosis and cancer prognosis.

Yoon has coauthored multiple papers with several frequent collaborators including Hakjoo Lee, Hiromi Sesaki, Sylvia B. Smith, Tae Jin Lee, and Chad A. Galloway.

The scientist's work has been published in several notable venues, reflecting the range and depth of their research focus. Frequent publication venues include:

  • Journal of Biological Chemistry
  • The FASEB Journal
  • Molecular Cell
  • Asia-Pacific Journal of Ophthalmology
  • Nature Communications

Among the recent papers authored or coauthored by Yisang Yoon are:

  • "The short variant of optic atrophy 1 (OPA1) improves cell survival under oxidative stress" (2020, Journal of Biological Chemistry)
  • "OPA1 promotes ferroptosis by augmenting mitochondrial ROS and suppressing an integrated stress response" (2024, Molecular Cell)
  • "Comparison Between an Intraocular Lens With Extended Depth of Focus (Tecnis Symfony ZXR00) and a New Monofocal Intraocular Lens With Enhanced Intermediate Vision (Tecnis Eyhance ICB00)" (2021, Asia-Pacific Journal of Ophthalmology)
  • "The mitochondrial fusion protein OPA1 is dispensable in the liver and its absence induces mitohormesis to protect liver from drug-induced injury" (2023, Nature Communications)
  • "Nucleus-mitochondria positive feedback loop formed by ERK5 S496 phosphorylation-mediated poly (ADP-ribose) polymerase activation provokes persistent pro-inflammatory senescent phenotype and accelerates coronary atherosclerosis after chemo-radiation" (2021, Redox Biology)

Best Publications

  • Calcium, ATP, and ROS: a mitochondrial love-hate triangle

    Paul S. Brookes;Yisang Yoon;James L. Robotham;M. W. Anders

  • Increased production of reactive oxygen species in hyperglycemic conditions requires dynamic change of mitochondrial morphology

    Tianzheng Yu;James L. Robotham;Yisang Yoon

  • The Mitochondrial Protein hFis1 Regulates Mitochondrial Fission in Mammalian Cells through an Interaction with the Dynamin-Like Protein DLP1

    Yisang Yoon;Eugene W. Krueger;Barbara J. Oswald;Mark A. McNiven

  • γ-tubulin is a component of the spindle pole body that is essential for microtubule function in Aspergillus nidulans

    Berl R. Oakley;C.Elizabeth Oakley;Yisang Yoon;M.Katherine Jung

  • Mitochondrial fission mediates high glucose-induced cell death through elevated production of reactive oxygen species.

    Tianzheng Yu;Shey Shing Sheu;James L. Robotham;Yisang Yoon

  • The dynamin family of mechanoenzymes: pinching in new places.

    Mark A McNiven;Hong Cao;Kelly R Pitts;Yisang Yoon

  • Dynamin-like protein 1 is involved in peroxisomal fission

    Annett Koch;Meinolf Thiemann;Markus Grabenbauer;Yisang Yoon

  • A Role for Fis1 in Both Mitochondrial and Peroxisomal Fission in Mammalian Cells

    Annett Koch;Yisang Yoon;Nina A. Bonekamp;Mark A. McNiven

  • The dynamin-like protein DLP1 is essential for normal distribution and morphology of the endoplasmic reticulum and mitochondria in mammalian cells.

    K.R. Pitts;Y. Yoon;E.W. Krueger;M.A. McNiven

  • Mammalian dynamin-like protein DLP1 tubulates membranes.

    Yisang Yoon;Kelly R. Pitts;Mark A. McNiven

  • Cytoplasmic dynein regulates the subcellular distribution of mitochondria by controlling the recruitment of the fission factor dynamin-related protein-1

    Aniko Varadi;Linda I. Johnson-Cadwell;Vincenzo Cirulli;Yisang Yoon

  • High-glucose stimulation increases reactive oxygen species production through the calcium and mitogen-activated protein kinase-mediated activation of mitochondrial fission.

    Tianzheng Yu;Bong Sook Jhun;Yisang Yoon

  • Mitochondrial Dynamics in Diabetes

    Yisang Yoon;Chad A. Galloway;Bong Sook Jhun;Tianzheng Yu

  • Perturbations in Mitochondrial Dynamics Induced by Human Mutant PINK1 Can Be Rescued by the Mitochondrial Division Inhibitor mdivi-1

    Mei Cui;Xiangna Tang;Whitney V. Christian;Yisang Yoon

  • A Novel Dynamin-like Protein Associates with Cytoplasmic Vesicles and Tubules of the Endoplasmic Reticulum in Mammalian Cells

    Yisang Yoon;Kelly R. Pitts;Sophie Dahan;Sophie Dahan;Mark A. McNiven

  • Regulation of mitochondrial fission and apoptosis by the mitochondrial outer membrane protein hFis1

    Tianzheng Yu;Randall J. Fox;Lindsay S. Burwell;Yisang Yoon

  • CaMKII induces permeability transition through Drp1 phosphorylation during chronic β-AR stimulation.

    Shangcheng Xu;Shangcheng Xu;Pei Wang;Huiliang Zhang;Guohua Gong

  • Mitochondrial fission and fusion.

    Hakjoo Lee;Yisang Yoon

  • Mitochondria and peroxisomes: are the 'big brother' and the 'little sister' closer than assumed?

    Michael Schrader;Yisang Yoon

  • Mitochondrial morphology-emerging role in bioenergetics.

    Chad A. Galloway;Hakjoo Lee;Yisang Yoon

Frequent Co-Authors

Mark A. McNiven
Mark A. McNiven Mayo Clinic
Shey-Shing Sheu
Shey-Shing Sheu Thomas Jefferson University
Zheng Dong
Zheng Dong Augusta University
Paul S. Brookes
Paul S. Brookes University of Rochester Medical Center
Berl R. Oakley
Berl R. Oakley University of Kansas
Sylvia B. Smith
Sylvia B. Smith Augusta University
Michael Schrader
Michael Schrader University of Exeter
Xiao Ming Yin
Xiao Ming Yin Indiana University
Tohru Fukai
Tohru Fukai Veterans Health Administration
Stephen M. Black
Stephen M. Black Florida International University

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