World's Best Scientists 2026 revealed!

D-Index & Metrics

Medicine

D-Index
76
Citations
27608
World Ranking
18656
National Ranking
9294

Overview

Leena Sharma is affiliated with Northwestern University in the United States. Their primary field of research is Medicine, with a focus on Rheumatology and Surgery. The scientist's work also covers Biomedical Engineering, Pharmacology, and Physiology as subfields of study.

The main topics reflected in their research output include:

  • Osteoarthritis Treatment and Mechanisms
  • Total Knee Arthroplasty Outcomes
  • Knee Injuries and Reconstruction Techniques
  • Lower Extremity Biomechanics and Pathologies
  • Orthopaedic Implants and Arthroplasty
  • Musculoskeletal Synovial Abnormalities and Treatments
  • Musculoskeletal Pain and Rehabilitation

Leena Sharma has contributed extensively to the understanding and treatment of knee osteoarthritis and related conditions. Among the recent papers authored or co-authored by Sharma are:

  • "Osteoarthritis of the Knee," 2021, New England Journal of Medicine
  • "Examining Timeliness of Total Knee Replacement Among Patients with Knee Osteoarthritis in the U.S.," 2020, Journal of Bone and Joint Surgery
  • "Association of Long-term Strenuous Physical Activity and Extensive Sitting With Incident Radiographic Knee Osteoarthritis," 2020, JAMA Network Open
  • "The Association Between Severity of Radiographic Knee OA and Recurrent Falls in Middle and Older Aged Adults: The Osteoarthritis Initiative," 2022, The Journals of Gerontology Series A
  • "Comparison of Evaluation Metrics of Deep Learning for Imbalanced Imaging Data in Osteoarthritis Studies," 2023, Osteoarthritis and Cartilage

The scientist frequently publishes in specialized venues related to musculoskeletal research, including:

  • Osteoarthritis and Cartilage
  • Osteoarthritis and Cartilage Open
  • Journal of Pain
  • Arthritis & Rheumatology
  • New England Journal of Medicine

Collaboration is a notable element in Sharma's academic work. Frequent co-authors include:

  • Alison H. Chang
  • Joan S. Chmiel
  • Orit Almagor
  • Ali Guermazi
  • Jungwha Lee

The focus on osteoarthritis, particularly knee osteoarthritis, extends across treatment modalities, surgical outcomes, biomechanics, and related pain management strategies. The body of research reflects a multidisciplinary approach bridging clinical and biomedical engineering perspectives. The scientist's work has been cited in several high-impact journals, indicating engagement with contemporary issues in musculoskeletal health and orthopaedic interventions.

Best Publications

  • Osteoarthritis: New Insights Part 1: The Disease and Its Risk Factors

    D. T. Felson;R. C. Lawrence;P. A. Dieppe;R. Hirsch

  • The Role of Knee Alignment in Disease Progression and Functional Decline in Knee Osteoarthritis

    Leena Sharma;Jing Song;David T. Felson;September Cahue

  • Leg symptoms in peripheral arterial disease: associated clinical characteristics and functional impairment.

    Mary Mc Grae McDermott;Philip Greenland;Kiang Liu;Jack M. Guralnik

  • KNEE ADDUCTION MOMENT, SERUM HYALURONAN LEVEL, AND DISEASE SEVERITY IN MEDIAL TIBIOFEMORAL OSTEOARTHRITIS

    Leena Sharma;Debra E. Hurwitz;Eugene J.M.A. Thonar;Jeffrey A. Sum

  • Physical functioning over three years in knee osteoarthritis: role of psychosocial, local mechanical, and neuromuscular factors.

    Leena Sharma;September Cahue;Jing Song;Karen Hayes

  • Osteoarthritis of the Knee

    Leena Sharma

  • Varus and valgus alignment and incident and progressive knee osteoarthritis

    Leena Sharma;Jing Song;Dorothy Dunlop;David Felson

  • Potential strategies to reduce medial compartment loading in patients with knee osteoarthritis of varying severity: reduced walking speed.

    Annegret Mündermann;Chris O. Dyrby;Debra E. Hurwitz;Leena Sharma

  • The mechanism of the effect of obesity in knee osteoarthritis: the mediating role of malalignment.

    Leena Sharma;Congrong Lou;September Cahue;Dorothy D. Dunlop

  • Effect of age and osteoarthritis on knee proprioception.

    Yi-Chung Pai;W. Zev Rymer;Rowland W. Chang;Leena Sharma

  • Epidemiology of osteoarthritis: An update

    Leena Sharma;Dipali Kapoor;Sakeba Issa

  • The relationship between specific tissue lesions and pain severity in persons with knee osteoarthritis.

    L. Torres;D.D. Dunlop;C. Peterfy;A. Guermazi

  • Quadriceps Strength and Osteoarthritis Progression in Malaligned and Lax Knees

    Leena Sharma;Dorothy D. Dunlop;September Cahue;Jing Song

  • The influence of alignment on risk of knee osteoarthritis progression according to baseline stage of disease

    Rui Cerejo;Dorothy D. Dunlop;September Cahue;David Channin

  • Knee pain and joint loading in subjects with osteoarthritis of the knee.

    D. E. Hurwitz;A. R. Ryals;A. R. Ryals;J. A. Block;L. Sharma

  • Hip abduction moment and protection against medial tibiofemoral osteoarthritis progression

    Alison Chang;Karen Hayes;Dorothy Dunlop;Jing Song

  • Laxity in healthy and osteoarthritic knees

    Leena Sharma;Congrong Lou;David T. Felson;Dorothy D. Dunlop

  • Effects of doxycycline on progression of osteoarthritis: Results of a randomized, placebo‐controlled, double‐blind trial

    Kenneth D. Brandt;Steven A. Mazzuca;Barry P. Katz;Kathleen A. Lane

  • Is obesity a risk factor for progressive radiographic knee osteoarthritis

    J. Niu;Y. Q. Zhang;J. Torner;M. Nevitt

  • Relationship of Meniscal Damage, Meniscal Extrusion, Malalignment, and Joint Laxity to Subsequent Cartilage Loss in Osteoarthritic Knees

    Leena Sharma;Felix Eckstein;Jing Song;Ali Guermazi

Frequent Co-Authors

Ali Guermazi
Ali Guermazi Boston University
Michael C. Nevitt
Michael C. Nevitt University of California, San Francisco
Joan S. Chmiel
Joan S. Chmiel Northwestern University
Frank W. Roemer
Frank W. Roemer University of Erlangen-Nuremberg
Felix Eckstein
Felix Eckstein Paracelsus Medical University
David T. Felson
David T. Felson Boston University
Rebecca D. Jackson
Rebecca D. Jackson The Ohio State University
Charles B. Eaton
Charles B. Eaton Brown University
Marc C. Hochberg
Marc C. Hochberg University of Maryland, Baltimore
Cora E. Lewis
Cora E. Lewis University of Alabama at Birmingham

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