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Biology and Biochemistry

D-Index
62
Citations
26858
World Ranking
10521
National Ranking
362

Overview

Heidi M. McBride is affiliated with the Montreal Neurological Institute and Hospital in Canada. Their research primarily spans the fields of Biochemistry, Genetics and Molecular Biology, and Medicine, with notable focus areas including Molecular Biology, Neurology, Physiology, Immunology, and Cellular and Molecular Neuroscience.

The scientist's work is centered on key topics such as:

  • Mitochondrial Function and Pathology
  • Parkinson's Disease Mechanisms and Treatments
  • Peroxisome Proliferator-Activated Receptors
  • Endoplasmic Reticulum Stress and Disease
  • Autophagy in Disease and Therapy
  • Interferon and Immune Responses
  • Cancer, Hypoxia, and Metabolism

Heidi M. McBride has contributed to several recent papers, including:

  • "MIROs and DRP1 drive mitochondrial-derived vesicle biogenesis and promote quality control" (2021) published in Nature Cell Biology
  • "Golgi-derived PI (4) P-containing vesicles drive late steps of mitochondrial division" (2020) published in Science
  • "Critical Role of Lipid Scramblase TMEM16F in Phosphatidylserine Exposure and Repair of Plasma Membrane after Pore Formation" (2020) published in Cell Reports
  • "Mitochondrial-derived vesicles in metabolism, disease, and aging" (2024) published in Cell Metabolism
  • "Recommendations for mitochondria transfer and transplantation nomenclature and characterization" (2025) published in Nature Metabolism

The scientist has frequently published in venues such as:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Cell Reports
  • Nature Cell Biology
  • Science
  • Cell Metabolism

Among frequent co-authors are:

  • Michel Desjardins
  • Sherilyn Junelle Recinto
  • Jo Anne Stratton
  • Olesia Ignatenko
  • Samantha Gruenheid

Best Publications

  • Rab proteins as membrane organizers

    Marino Zerial;Heidi McBride

  • Mitochondria: more than just a powerhouse.

    Heidi M. McBride;Margaret Neuspiel;Sylwia Wasiak

  • The Rab5 effector EEA1 is a core component of endosome docking

    Savvas Christoforidis;Heidi M. McBride;Robert D. Burgoyne;Marino Zerial

  • The PINK1/Parkin pathway regulates mitochondrial morphology

    Angela C. Poole;Ruth E. Thomas;Laurie A. Andrews;Heidi M. McBride

  • A new pathway for mitochondrial quality control: mitochondrial‐derived vesicles

    Ayumu Sugiura;Gian-Luca McLelland;Edward A Fon;Heidi M McBride

  • A Novel Rab5 GDP/GTP Exchange Factor Complexed to Rabaptin-5 Links Nucleotide Exchange to Effector Recruitment and Function

    Hisanori Horiuchi;Roger Lippé;Heidi M. McBride;Mariantonietta Rubino

  • A Vesicular Transport Pathway Shuttles Cargo from Mitochondria to Lysosomes

    Vincent Soubannier;Gian Luca McLelland;Rodolfo Zunino;Emelie Braschi

  • Mitochondrial processing peptidase regulates PINK1 processing, import and Parkin recruitment

    Andrew W Greene;Karl Grenier;Miguel A Aguileta;Stephanie Muise

  • Oligomeric Complexes Link Rab5 Effectors with NSF and Drive Membrane Fusion via Interactions between EEA1 and Syntaxin 13

    Heidi M McBride;Vladimir Rybin;Carol Murphy;Angelika Giner

  • Parkin and PINK1 function in a vesicular trafficking pathway regulating mitochondrial quality control.

    Gian-Luca McLelland;Vincent Soubannier;Carol X Chen;Heidi M McBride

  • Bax/Bak promote sumoylation of DRP1 and its stable association with mitochondria during apoptotic cell death.

    Sylwia Wasiak;Rodolfo Zunino;Heidi M. McBride

  • Cargo-selected transport from the mitochondria to peroxisomes is mediated by vesicular carriers.

    Margaret Neuspiel;Astrid C. Schauss;Emelie Braschi;Rodolfo Zunino

  • Parkinson’s Disease-Related Proteins PINK1 and Parkin Repress Mitochondrial Antigen Presentation

    Diana Matheoud;Ayumu Sugiura;Angélique Bellemare-Pelletier;Annie Laplante

  • Intestinal infection triggers Parkinson’s disease-like symptoms in Pink1 −/− mice

    Diana Matheoud;Tyler Cannon;Aurore Voisin;Anna-Maija Penttinen

  • Loss of the Parkinson’s Disease-linked gene DJ-1 perturbs mitochondrial dynamics

    I. Irrcher;H. Aleyasin;E.L. Seifert;S.J. Hewitt

  • Sumo1 Conjugates Mitochondrial Substrates and Participates in Mitochondrial Fission

    Zdena Harder;Rodolfo Zunino;Heidi McBride

  • Activated Mitofusin 2 Signals Mitochondrial Fusion, Interferes with Bax Activation, and Reduces Susceptibility to Radical Induced Depolarization

    Margaret Neuspiel;Rodolfo Zunino;Sandhya Gangaraju;Peter Rippstein

  • MAPL is a new mitochondrial SUMO E3 ligase that regulates mitochondrial fission

    Emélie Braschi;Rodolfo Zunino;Heidi M McBride

  • Endoplasmic reticulum BIK initiates DRP1-regulated remodelling of mitochondrial cristae during apoptosis.

    Marc Germain;Jaigi P Mathai;Heidi M McBride;Gordon C Shore

  • OPA1-dependent cristae modulation is essential for cellular adaptation to metabolic demand.

    David A Patten;Jacob Wong;Mireille Khacho;Vincent Soubannier

Frequent Co-Authors

Gordon C. Shore
Gordon C. Shore McGill University
Aled M. Edwards
Aled M. Edwards Structural Genomics Consortium
David S. Park
David S. Park New York University
Ruth S. Slack
Ruth S. Slack University of Ottawa
Eric A. Shoubridge
Eric A. Shoubridge Montreal Neurological Institute and Hospital
Marino Zerial
Marino Zerial Max Planck Society
Miguel A. Andrade-Navarro
Miguel A. Andrade-Navarro Johannes Gutenberg University of Mainz
Christine Des Rosiers
Christine Des Rosiers University of Montreal
Anne-Claude Gingras
Anne-Claude Gingras Lunenfeld-Tanenbaum Research Institute
Opher Gileadi
Opher Gileadi Karolinska Institute

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