Eric A. Shoubridge

Research.com Recognitions

• 2004 - Fellow of the Royal Society of Canada Academy of Science

Overview

Best Publications

• SURF1, encoding a factor involved in the biogenesis of cytochrome c oxidase, is mutated in Leigh syndrome.

  Zhiqing Zhu;Jianbo Yao;T. Johns;K. Fu

  754
  Citations

• Random genetic drift in the female germline explains the rapid segregation of mammalian mitochondrial DNA.

  Jack P. Jenuth;Alan C. Peterson;Alan C. Peterson;Katherine Fu;Katherine Fu;Eric A. Shoubridge;Eric A. Shoubridge

  696
  Citations

• The mitochondrial DNA genetic bottleneck results from replication of a subpopulation of genomes

  Timothy Wai;Daniella Teoli;Eric A Shoubridge

  507
  Citations

• Identification of the gene responsible for methylmalonic aciduria and homocystinuria, cblC type.

  Jordan P Lerner-Ellis;Jamie C Tirone;Jamie C Tirone;Peter D Pawelek;Carole Doré

  450
  Citations

• Tissue-specific selection for different mtDNA genotypes in heteroplasmic mice

  Jack P. Jenuth;Alan C. Peterson;Eric A. Shoubridge;Eric A. Shoubridge

  449
  Citations

• The Role of Mitochondrial DNA Copy Number in Mammalian Fertility

  Timothy Wai;Asangla Ao;Xiaoyun Zhang;Daniel G. Cyr

  443
  Citations

• The Mitochondrial Transcription Factor TFAM Coordinates the Assembly of Multiple DNA Molecules into Nucleoid-like Structures

  Brett A. Kaufman;Nela Durisic;Jeffrey M. Mativetsky;Santiago Costantino

  436
  Citations

• Evolutionary conservation of the clk-1-dependent mechanism of longevity: loss of mclk1 increases cellular fitness and lifespan in mice

  Xingxing Liu;Ning Jiang;Bryan Hughes;Eve Bigras

  398
  Citations

• Cytochrome c oxidase deficiency.

  Eric A. Shoubridge

  396
  Citations

• Distribution and threshold expression of the tRNA(Lys) mutation in skeletal muscle of patients with myoclonic epilepsy and ragged-red fibers (MERRF).

  L Boulet;G Karpati;E A Shoubridge

  395
  Citations

• Mutations in COX15 produce a defect in the mitochondrial heme biosynthetic pathway, causing early-onset fatal hypertrophic cardiomyopathy.

  Hana Antonicka;Andre Mattman;Christopher G. Carlson;D. Moira Glerum

  379
  Citations

• Myoblast transfer in duchenne muscular dystrophy

  George Karpati;Djordje Ajdukovic;Douglas Arnold;Robert B. Gledhill

  378
  Citations

• Mitochondrial RNA Granules Are Centers for Posttranscriptional RNA Processing and Ribosome Biogenesis

  Hana Antonicka;Eric A. Shoubridge

  346
  Citations

• Mutations in Iron-Sulfur Cluster Scaffold Genes NFU1 and BOLA3 Cause a Fatal Deficiency of Multiple Respiratory Chain and 2-Oxoacid Dehydrogenase Enzymes

  Jessie M. Cameron;Alexandre Janer;Valeriy Levandovskiy;Nevena MacKay

  344
  Citations

• A proximity-dependent biotinylation map of a human cell.

  Christopher D. Go;Christopher D. Go;James D. R. Knight;Archita Rajasekharan;Bhavisha Rathod

  344
  Citations

• A molecular chaperone for mitochondrial complex I assembly is mutated in a progressive encephalopathy

  Isla Ogilvie;Nancy G. Kennaway;Eric A. Shoubridge

  341
  Citations

• Mitochondrial DNA and the mammalian oocyte.

  Eric A Shoubridge;Timothy Wai

  336
  Citations

• Mutation in TACO1, encoding a translational activator of COX I, results in cytochrome c oxidase deficiency and late-onset Leigh syndrome.

  Woranontee Weraarpachai;Hana Antonicka;Florin Sasarman;Florin Sasarman;Jürgen Seeger

  334
  Citations

• Reconstitution of Mitochondria Derived Vesicle Formation Demonstrates Selective Enrichment of Oxidized Cargo

  Vincent Soubannier;Peter Rippstein;Brett A. Kaufman;Eric A. Shoubridge

  314
  Citations

• Deletion mutants are functionally dominant over wild-type mitochondrial genomes in skeletal muscle fiber segments in mitochondrial disease

  Eric A. Shoubridge;George Karpati;Kenneth E.M. Hastings;Kenneth E.M. Hastings

  303
  Citations