D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 56 Citations 8,279 92 World Ranking 7294 National Ranking 174

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Enzyme
  • Mutation

His scientific interests lie mostly in Mitochondrion, Oxidative phosphorylation, Cell biology, Biochemistry and Biogenesis. His work deals with themes such as Mutation, Molecular biology and Protein subunit, which intersect with Mitochondrion. His biological study spans a wide range of topics, including Complementation, Internal medicine, Endoplasmic reticulum and Intracellular.

The concepts of his Oxidative phosphorylation study are interwoven with issues in Oxidoreductase, Respiratory chain, Function and Mitochondrial DNA. He has included themes like RNA interference and Neurospora crassa in his Cell biology study. He has researched Biogenesis in several fields, including Oxoglutarate dehydrogenase complex and Beta oxidation.

His most cited work include:

  • Blue Native electrophoresis to study mitochondrial and other protein complexes. (333 citations)
  • Mammalian Mitochondrial Complex I: Biogenesis, Regulation, and Reactive Oxygen Species Generation (292 citations)
  • Mitochondrial complex I: structure, function and pathology. (214 citations)

What are the main themes of his work throughout his whole career to date?

His primary areas of study are Mitochondrion, Genetics, Oxidative phosphorylation, Molecular biology and Mutation. His Mitochondrion study combines topics in areas such as NDUFS4, Biogenesis and Mitochondrial DNA. His Oxidative phosphorylation research entails a greater understanding of Biochemistry.

His Molecular biology study also includes fields such as

  • Protein subunit that intertwine with fields like DNA Mutational Analysis,
  • Coenzyme Q – cytochrome c reductase which is related to area like Cytochrome b. His Mutation research is multidisciplinary, relying on both Complementation, Endocrinology and Candidate gene. In the field of Cell biology, his study on Inner mitochondrial membrane overlaps with subjects such as Fluorescence recovery after photobleaching.

He most often published in these fields:

  • Mitochondrion (46.15%)
  • Genetics (34.62%)
  • Oxidative phosphorylation (31.73%)

What were the highlights of his more recent work (between 2016-2021)?

  • Oxidative phosphorylation (31.73%)
  • Cell biology (25.00%)
  • Genetics (34.62%)

In recent papers he was focusing on the following fields of study:

Leo G.J. Nijtmans spends much of his time researching Oxidative phosphorylation, Cell biology, Genetics, Protein subunit and Inner mitochondrial membrane. His study in Oxidative phosphorylation is interdisciplinary in nature, drawing from both Gene and Mitochondrial DNA. His work on Golgi apparatus as part of his general Cell biology study is frequently connected to Extracellular matrix assembly, thereby bridging the divide between different branches of science.

His study focuses on the intersection of Protein subunit and fields such as Molecular biology with connections in the field of Mutation and Complementation. His work in Mutation covers topics such as Biogenesis which are related to areas like Mitochondrion. His Inner mitochondrial membrane research integrates issues from Protein complex assembly and Protein family.

Between 2016 and 2021, his most popular works were:

  • The Assembly Pathway of Mitochondrial Respiratory Chain Complex I. (182 citations)
  • Mutations in ATP6V1E1 or ATP6V1A Cause Autosomal-Recessive Cutis Laxa (50 citations)
  • Bi-allelic Mutations in the Mitochondrial Ribosomal Protein MRPS2 Cause Sensorineural Hearing Loss, Hypoglycemia, and Multiple OXPHOS Complex Deficiencies (27 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Enzyme
  • Mutation

The scientist’s investigation covers issues in Protein subunit, Oxidative phosphorylation, Mitochondrial respiratory chain complex I, Cell biology and Molecular biology. His Protein subunit research includes themes of Multiprotein complex, Biosynthesis, Nuclear gene, Respiratory chain and Computational biology. His Oxidative phosphorylation study integrates concerns from other disciplines, such as Mitochondrial matrix, Ribosomal protein, Gene mutation, Gene and Mitochondrial translation.

As part of his inquiry into Mitochondrion and Genetics, Leo G.J. Nijtmans is doing Mitochondrial respiratory chain complex I research. His research integrates issues of Ribosome, Cutis laxa and Mitochondrial disease in his study of Cell biology. In Molecular biology, Leo G.J. Nijtmans works on issues like Exome sequencing, which are connected to Complementation.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Blue Native electrophoresis to study mitochondrial and other protein complexes.

Leo G J Nijtmans;Nadine S Henderson;Ian J Holt.
Methods (2002)

410 Citations

Mammalian Mitochondrial Complex I: Biogenesis, Regulation, and Reactive Oxygen Species Generation

Werner J.H. Koopman;Leo G.J. Nijtmans;Cindy E.J. Dieteren;Peggy Roestenberg.
Antioxidants & Redox Signaling (2010)

408 Citations

Mitochondrial complex I: structure, function and pathology.

Rolf J. R. J. Janssen;Leo G. Nijtmans;Lambert P. van den Heuvel;Jan A. M. Smeitink.
Journal of Inherited Metabolic Disease (2006)

295 Citations

The Mitochondrial Prohibitin Complex Is Essential for Embryonic Viability and Germline Function in Caenorhabditis elegans

Marta Artal Sanz;William Y. Tsang;Esther M. Willems;Les A. Grivell.
Journal of Biological Chemistry (2003)

259 Citations

Differences in assembly or stability of complex I and other mitochondrial OXPHOS complexes in inherited complex I deficiency

Cristina Ugalde;Rolf J.R.J. Janssen;Lambert P. van den Heuvel;Jan A.M. Smeitink.
Human Molecular Genetics (2004)

229 Citations

The Assembly Pathway of Mitochondrial Respiratory Chain Complex I.

Sergio Guerrero-Castillo;Sergio Guerrero-Castillo;Fabian Baertling;Fabian Baertling;Daniel Kownatzki;Hans J. Wessels.
Cell Metabolism (2017)

222 Citations

Cytosolic signaling protein Ecsit also localizes to mitochondria where it interacts with chaperone NDUFAF1 and functions in complex I assembly.

R.O. Vogel;R.J.R.J. Janssen;M.A.M. van den Brand;C.E.J. Dieteren.
Genes & Development (2007)

219 Citations

Human mitochondrial complex I assembles through the combination of evolutionary conserved modules: a framework to interpret complex I deficiencies

Cristina Ugalde;Rutger Vogel;Richard Huijbens;Bert van den Heuvel.
Human Molecular Genetics (2004)

216 Citations

Identification of mitochondrial complex I assembly intermediates by tracing tagged NDUFS3 demonstrates the entry point of mitochondrial subunits.

Rutger O. Vogel;Cindy E.J. Dieteren;Lambert P. W.J. van den Heuvel;Peter H. G.M. Willems.
Journal of Biological Chemistry (2007)

193 Citations

Mutations in NDUFAF3 (C3ORF60), encoding an NDUFAF4 (C6ORF66)-interacting complex I assembly protein, cause fatal neonatal mitochondrial disease.

Ann Saada;Rutger O. Vogel;Saskia J. Hoefs;Mariël A. van den Brand.
American Journal of Human Genetics (2009)

189 Citations

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