D-Index & Metrics Best Publications
Biology and Biochemistry
Netherlands
2023

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 71 Citations 18,040 283 World Ranking 4154 National Ranking 94

Research.com Recognitions

Awards & Achievements

2023 - Research.com Biology and Biochemistry in Netherlands Leader Award

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Enzyme
  • DNA

His primary areas of investigation include Cell biology, Mitochondrion, Oxidative phosphorylation, Biochemistry and Reactive oxygen species. Peter H.G.M. Willems has included themes like Membrane potential and Cytosol in his Cell biology study. His Mitochondrion research includes elements of Mutation, Cell and Superoxide.

His biological study spans a wide range of topics, including Biogenesis, Oxidoreductase, Leigh disease, Metabolic pathway and Fibroblast. His work deals with themes such as Oxidative stress and Cell signaling, which intersect with Reactive oxygen species. Peter H.G.M. Willems focuses mostly in the field of TRPV5, narrowing it down to matters related to Calcitriol and, in some cases, Connecting tubule and Endocrinology.

His most cited work include:

  • mTOR- and HIF-1α–mediated aerobic glycolysis as metabolic basis for trained immunity (827 citations)
  • Molecular Identification of the Apical Ca2+Channel in 1,25-Dihydroxyvitamin D3-responsive Epithelia * (519 citations)
  • Monogenic Mitochondrial Disorders (348 citations)

What are the main themes of his work throughout his whole career to date?

Cell biology, Biochemistry, Mitochondrion, Internal medicine and Endocrinology are his primary areas of study. Peter H.G.M. Willems interconnects Xenopus and Cytosol in the investigation of issues within Cell biology. Peter H.G.M. Willems combines subjects such as Molecular biology and Biophysics with his study of Biochemistry.

His Biophysics research is multidisciplinary, incorporating elements of Calcium and Inositol. His Mitochondrion research incorporates elements of Cell, Reactive oxygen species, Oxidative phosphorylation, Membrane potential and Mitochondrial disease. The various areas that Peter H.G.M. Willems examines in his Endocrinology study include Cholecystokinin, Receptor and Protein kinase C.

He most often published in these fields:

  • Cell biology (30.85%)
  • Biochemistry (28.14%)
  • Mitochondrion (26.78%)

What were the highlights of his more recent work (between 2013-2021)?

  • Mitochondrion (26.78%)
  • Cell biology (30.85%)
  • Oxidative phosphorylation (16.27%)

In recent papers he was focusing on the following fields of study:

His primary areas of study are Mitochondrion, Cell biology, Oxidative phosphorylation, Biochemistry and Cell. His research in Mitochondrion intersects with topics in Bioinformatics, NDUFS4, Adenosine triphosphate, Function and Membrane potential. His Cell biology study combines topics from a wide range of disciplines, such as Electron transport chain, Ferroptosis and Necroptosis.

His Oxidative phosphorylation research is multidisciplinary, incorporating perspectives in Endocrinology, In vitro, Inner mitochondrial membrane, Internal medicine and Mitochondrial disease. His work in the fields of Cytosol, NADH-Ubiquinone Oxidoreductase, Carbohydrate metabolism and Citric acid cycle overlaps with other areas such as Trolox. His work in Reactive oxygen species addresses subjects such as Oxidative stress, which are connected to disciplines such as Intracellular.

Between 2013 and 2021, his most popular works were:

  • mTOR- and HIF-1α–mediated aerobic glycolysis as metabolic basis for trained immunity (827 citations)
  • Redox Homeostasis and Mitochondrial Dynamics. (254 citations)
  • Broad defects in the energy metabolism of leukocytes underlie immunoparalysis in sepsis (245 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Enzyme
  • DNA

Peter H.G.M. Willems spends much of his time researching Mitochondrion, Oxidative phosphorylation, Cell biology, Biochemistry and Cell. His Mitochondrion research incorporates themes from Bioinformatics, Adenosine triphosphate, Function, Melanoma and In vivo. His study focuses on the intersection of Adenosine triphosphate and fields such as Cellular respiration with connections in the field of Internal medicine and Endocrinology.

In Oxidative phosphorylation, Peter H.G.M. Willems works on issues like Mitochondrial disease, which are connected to Rational design, Drug development, Complementation and Drug discovery. A large part of his Cell biology studies is devoted to Mitochondrial Complex I. The Cell study combines topics in areas such as Lamin, Phenotype, Microscopy, Leigh disease and Citrate synthase.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

mTOR- and HIF-1α–mediated aerobic glycolysis as metabolic basis for trained immunity

Shih-Chin Cheng;Jessica Quintin;Robert A. Cramer;Kelly M. Shepardson.
(2014)

1359 Citations

Molecular Identification of the Apical Ca2+Channel in 1,25-Dihydroxyvitamin D3-responsive Epithelia *

J.G.J. Hoenderop;J.W.C.M. van der Kemp;A. Hartog;K.F.J. van de Graaf.
Journal of Biological Chemistry (1999)

816 Citations

Redox Homeostasis and Mitochondrial Dynamics.

Peter H.G.M. Willems;Rodrigue Rossignol;Cindy E.J. Dieteren;Michael P. Murphy.
Cell Metabolism (2015)

546 Citations

Monogenic Mitochondrial Disorders

Werner J H Koopman;Peter H G M Willems;Jan A M Smeitink.
The New England Journal of Medicine (2012)

520 Citations

Mammalian Mitochondrial Complex I: Biogenesis, Regulation, and Reactive Oxygen Species Generation

Werner J.H. Koopman;Leo G.J. Nijtmans;Cindy E.J. Dieteren;Peggy Roestenberg.
Antioxidants & Redox Signaling (2010)

435 Citations

Mitochondrial function and morphology are impaired in parkin mutant fibroblasts

Heather Mortiboys;Kelly Jean Thomas;Werner J. H. Koopman;Stefanie Klaffke.
Annals of Neurology (2008)

398 Citations

Broad defects in the energy metabolism of leukocytes underlie immunoparalysis in sepsis

Shih Chin Cheng;Brendon P. Scicluna;Rob J W Arts;Mark S. Gresnigt.
Nature Immunology (2016)

382 Citations

Mitochondrial complex I deficiency: from organelle dysfunction to clinical disease

Felix Distelmaier;Felix Distelmaier;Werner J.H. Koopman;Lambertus P. van den Heuvel;Richard J. Rodenburg.
Brain (2008)

345 Citations

Permeation and gating properties of the novel epithelial Ca(2+) channel.

Rudi Vennekens;Joost G.J. Hoenderop;Jean Prenen;Marchel Stuiver.
Journal of Biological Chemistry (2000)

343 Citations

Coxsackievirus protein 2B modifies endoplasmic reticulum membrane and plasma membrane permeability and facilitates virus release

F.J.M. van Kuppeveld;J.G.J. Hoenderop;R.L.L. Smeets;P.H.G.M. Willems.
The EMBO Journal (1997)

339 Citations

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