Peter H. G. M. Willems

Research.com Recognitions

• 2023 - Research.com Biology and Biochemistry in Netherlands Leader Award

Overview

Best Publications

• mTOR- and HIF-1α–mediated aerobic glycolysis as metabolic basis for trained immunity

  Shih-Chin Cheng;Jessica Quintin;Robert A. Cramer;Kelly M. Shepardson

  2188
  Citations

• Molecular Identification of the Apical Ca2+Channel in 1,25-Dihydroxyvitamin D3-responsive Epithelia *

  J.G.J. Hoenderop;J.W.C.M. van der Kemp;A. Hartog;K.F.J. van de Graaf

  837
  Citations

• Redox Homeostasis and Mitochondrial Dynamics.

  Peter H.G.M. Willems;Rodrigue Rossignol;Cindy E.J. Dieteren;Michael P. Murphy

  780
  Citations

• Broad defects in the energy metabolism of leukocytes underlie immunoparalysis in sepsis

  Shih Chin Cheng;Brendon P. Scicluna;Rob J W Arts;Mark S. Gresnigt

  605
  Citations

• Monogenic Mitochondrial Disorders

  Werner J H Koopman;Peter H G M Willems;Jan A M Smeitink

  568
  Citations

• Mitochondrial complex I inhibition triggers a mitophagy-dependent ROS increase leading to necroptosis and ferroptosis in melanoma cells.

  Farhan Basit;Lisanne Mpe van Oppen;Laura Schöckel;Hasse M Bossenbroek

  495
  Citations

• Mammalian Mitochondrial Complex I: Biogenesis, Regulation, and Reactive Oxygen Species Generation

  Werner J.H. Koopman;Leo G.J. Nijtmans;Cindy E.J. Dieteren;Peggy Roestenberg

  470
  Citations

• Mitochondrial function and morphology are impaired in parkin mutant fibroblasts

  Heather Mortiboys;Kelly Jean Thomas;Werner J. H. Koopman;Stefanie Klaffke

  425
  Citations

• Interactions between mitochondrial reactive oxygen species and cellular glucose metabolism

  Dania C. Liemburg-Apers;Peter H. G. M. Willems;Werner J. H. Koopman;Sander Grefte;Sander Grefte

  391
  Citations

• Permeation and gating properties of the novel epithelial Ca(2+) channel.

  Rudi Vennekens;Joost G.J. Hoenderop;Jean Prenen;Marchel Stuiver

  380
  Citations

• Mitochondrial complex I deficiency: from organelle dysfunction to clinical disease

  Felix Distelmaier;Felix Distelmaier;Werner J.H. Koopman;Lambertus P. van den Heuvel;Richard J. Rodenburg

  367
  Citations

• Coxsackievirus protein 2B modifies endoplasmic reticulum membrane and plasma membrane permeability and facilitates virus release

  F.J.M. van Kuppeveld;J.G.J. Hoenderop;R.L.L. Smeets;P.H.G.M. Willems

  359
  Citations

• Calcitriol Controls the Epithelial Calcium Channel in Kidney

  Joost G. J. Hoenderop;Dominik Müller;Annemiete W. C. M. Van Der Kemp;Anita Hartog

  342
  Citations

• Inhibition of complex I of the electron transport chain causes O2−·-mediated mitochondrial outgrowth

  Werner J. H. Koopman;Sjoerd Verkaart;Henk-Jan Visch;Francois H. van der Westhuizen

  332
  Citations

• OXPHOS mutations and neurodegeneration

  Werner J H Koopman;Felix Distelmaier;Jan A M Smeitink;Peter H G M Willems

  311
  Citations

• Localization of the Epithelial Ca2+ Channel in Rabbit Kidney and Intestine

  Joost G. J. Hoenderop;Anita Hartog;Marchel Stuiver;Alain Doucet

  259
  Citations

• Cytosolic signaling protein Ecsit also localizes to mitochondria where it interacts with chaperone NDUFAF1 and functions in complex I assembly.

  Rutger O. Vogel;Rolf J.R.J. Janssen;Mariël A.M. van den Brand;Cindy E.J. Dieteren

  257
  Citations

• Mitochondrial network complexity and pathological decrease in complex I activity are tightly correlated in isolated human complex I deficiency

  Werner J. H. Koopman;Henk-Jan Visch;Sjoerd Verkaart;Lambertus W. P. J. van den Heuvel

  253
  Citations

• Statin-Induced Myopathy Is Associated with Mitochondrial Complex III Inhibition

  Tom J.J. Schirris;G. Herma Renkema;Tina Ritschel;Nicol C. Voermans

  231
  Citations

• Acyl-CoA Dehydrogenase 9 Is Required for the Biogenesis of Oxidative Phosphorylation Complex I

  Jessica Nouws;Leo Nijtmans;Sander M. Houten;Mariël van den Brand

  217
  Citations