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René J. M. Bindels

René J. M. Bindels

D-Index & Metrics

Medicine

D-Index
97
Citations
34371
World Ranking
9287
National Ranking
360

Research.com Recognitions

  • 2005 - Member of Academia Europaea

Overview

René J. M. Bindels is affiliated with Radboud University in the Netherlands and has produced a significant body of research primarily in the fields of Biochemistry, Genetics and Molecular Biology, and Medicine. Their work spans various subfields including Molecular Biology, Nutrition and Dietetics, Plant Science, Genetics, and Surgery.

Their research interests focus notably on topics such as Magnesium in Health and Disease, Ion Transport and Channel Regulation, Extracellular Vesicles in Disease, Aluminum Toxicity and Tolerance in Plants and Animals, Mitochondrial Function and Pathology, Metabolism and Genetic Disorders, and Genetic and Kidney Cyst Diseases.

René J. M. Bindels has authored multiple papers in respected journals. Recent publications include:

  • Comparing Approaches to Normalize, Quantify, and Characterize Urinary Extracellular Vesicles, 2021, Journal of the American Society of Nephrology
  • Sensing of tubular flow and renal electrolyte transport, 2020, Nature Reviews Nephrology
  • Structural and functional comparison of magnesium transporters throughout evolution, 2022, Cellular and Molecular Life Sciences
  • Mechanisms coupling sodium and magnesium reabsorption in the distal convoluted tubule of the kidney, 2020, Acta Physiologica
  • Tacrolimus-induced hypomagnesemia and hypercalciuria requires FKBP12 suggesting a role for calcineurin, 2020, Physiological Reports

The scientist frequently publishes in several venues, with multiple contributions to the Journal of the American Society of Nephrology, Scientific Reports, The FASEB Journal, Journal of Hypertension, and Nature Reviews Nephrology.

Collaboration plays a significant role in their research. Common co-authors include Jeroen H. F. de Baaij, Joost G.J. Hoenderop, Gijs A. C. Franken, Daan H.H.M. Viering, and Juan Pablo Rigalli.

René J. M. Bindels was recognized as a Member of Academia Europaea in 2005.

Best Publications

  • Magnesium in Man: Implications for Health and Disease

    Jeroen H. F. de Baaij;Joost G. J. Hoenderop;René J. M. Bindels

  • Calcium Absorption Across Epithelia

    Joost G. J. Hoenderop;Bernd Nilius;René J. M. Bindels

  • Molecular Identification of the Apical Ca2+Channel in 1,25-Dihydroxyvitamin D3-responsive Epithelia *

    J.G.J. Hoenderop;J.W.C.M. van der Kemp;A. Hartog;K.F.J. van de Graaf

  • A Unified Nomenclature for the Superfamily of TRP Cation Channels

    Craig Montell;Lutz Birnbaumer;Veit Flockerzi;René J. Bindels

  • Duodenal calcium absorption in vitamin D receptor-knockout mice: functional and molecular aspects.

    Sophie J. Van Cromphaut;Mieke Dewerchin;Joost G. J. Hoenderop;Ingrid Stockmans

  • Mutations in CYP24A1 and Idiopathic Infantile Hypercalcemia

    Karl P. Schlingmann;Martin Kaufmann;Stefanie Weber;Andrew Irwin

  • TRPM6 forms the Mg2+ influx channel involved in intestinal and renal Mg2+ absorption.

    Thomas Voets;Bernd Nilius;Susan Hoefs;Annemiete W.C.M. van der Kemp

  • The MRP4/ABCC4 Gene Encodes a Novel Apical Organic Anion Transporter in Human Kidney Proximal Tubules: Putative Efflux Pump for Urinary cAMP and cGMP

    Rémon A. M. H. van Aubel;Pascal H. E. Smeets;Janny G. P. Peters;René J. M. Bindels

  • Enhanced passive Ca2+ reabsorption and reduced Mg2+ channel abundance explains thiazide-induced hypocalciuria and hypomagnesemia

    Tom Nijenhuis;Volker Vallon;Annemiete W.C.M. van der Kemp;Johannes Loffing

  • Renal Ca2+ wasting, hyperabsorption, and reduced bone thickness in mice lacking TRPV5.

    Joost G.J. Hoenderop;Johannes P.T.M. van Leeuwen;Bram C.J. van der Eerden;Ferry F.J. Kersten

  • Homo‐ and heterotetrameric architecture of the epithelial Ca2+ channels TRPV5 and TRPV6

    J G J Hoenderop;Thomas Voets;S Hoefs;F Weidema

  • Impaired basolateral sorting of pro-EGF causes isolated recessive renal hypomagnesemia

    Wouter M. Tiel Groenestege;Stéphanie Thébault;Jenny van der Wijst;Dennis van den Berg

  • Function and expression of the epithelial Ca2+ channel family: comparison of mammalian ECaC1 and 2

    Joost G. J. Hoenderop;Rudi Vennekens;Dominik Müller;Jean Prenen

  • Calcitriol Controls the Epithelial Calcium Channel in Kidney

    Joost G. J. Hoenderop;Dominik Müller;Annemiete W. C. M. Van Der Kemp;Anita Hartog

  • Functional expression of the epithelial Ca(2+) channels (TRPV5 and TRPV6) requires association of the S100A10-annexin 2 complex.

    Stan F.J. van de Graaf;Joost G.J. Hoenderop;Dimitra Gkika;Dennis Lamers

  • Modulation of renal Ca2+ transport protein genes by dietary Ca2+ and 1,25-dihydroxyvitamin D3 in 25-hydroxyvitamin D3-1alpha-hydroxylase knockout mice.

    Joost G J Hoenderop;Olivier Dardenne;Monique Van Abel;Annemiete W C M Van Der Kemp

  • Dominant isolated renal magnesium loss is caused by misrouting of the Na+,K+-ATPase gamma-subunit.

    I C Meij;J B Koenderink;H van Bokhoven;K F Assink

  • Distribution of transcellular calcium and sodium transport pathways along mouse distal nephron.

    Johannes Loffing;Dominique Loffing-Cueni;Victor Valderrabano;L. E. A. Kläusli

  • Hypomagnesemia in Type 2 Diabetes: A Vicious Circle?

    Lisanne M.M. Gommers;Joost G.J. Hoenderop;René J.M. Bindels;Jeroen H.F. de Baaij;Jeroen H.F. de Baaij

  • Molecular Mechanism of Active Ca2+ Reabsorption in the Distal Nephron

    Joost G J Hoenderop;Bernd Nilius;Rene J M Bindels

Frequent Co-Authors

Joost G. J. Hoenderop
Joost G. J. Hoenderop Radboud University
Nine V.A.M. Knoers
Nine V.A.M. Knoers University Medical Center Groningen
Bernd Nilius
Bernd Nilius KU Leuven
Peter H. G. M. Willems
Peter H. G. M. Willems Radboud University
Olivier Devuyst
Olivier Devuyst University of Zurich
Jean Prenen
Jean Prenen KU Leuven
Guy Droogmans
Guy Droogmans KU Leuven
Dominik N. Müller
Dominik N. Müller Max Delbrück Center for Molecular Medicine
C.H. van Os
C.H. van Os Radboud University
Hanka Venselaar
Hanka Venselaar Radboud University

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