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Matthias A. Hediger

Matthias A. Hediger

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Biology and Biochemistry
Switzerland
2023

D-Index & Metrics

Biology and Biochemistry

D-Index
109
Citations
51824
World Ranking
992
National Ranking
19

Research.com Recognitions

  • 2023 - Research.com Biology and Biochemistry in Switzerland Leader Award

Overview

Matthias A. Hediger is affiliated with the University of Bern in Switzerland. Their research primarily spans the fields of Biochemistry, Genetics and Molecular Biology, and Medicine, with a substantial focus on Materials Chemistry, Biochemistry, Molecular Biology, Sensory Systems, and Oncology as key subfields. Their scholarly work engages multiple topics including Crystallization and Solubility Studies, X-ray Diffraction in Crystallography, Amino Acid Enzymes and Metabolism, Ion Channels and Receptors, Drug Transport and Resistance Mechanisms, Neurobiology and Insect Physiology Research, and Trace Elements in Health.

The scientist has contributed to a significant number of publications in highly specialized venues. Their frequent publication outlets include:

  • The Cambridge Structural Database (13 publications)
  • Journal of Biological Chemistry (4 publications)
  • Preprints.org (4 publications)
  • bioRxiv (Cold Spring Harbor Laboratory) (4 publications)
  • Biomolecules (2 publications)

Among recent research papers attributed to Matthias A. Hediger or featuring their collaboration, key studies are:

  • "Sodium-coupled glucose transport, the SLC5 family, and therapeutically relevant inhibitors: from molecular discovery to clinical application," published in 2020 in Pflügers Archiv - European Journal of Physiology
  • "Genetic studies of paired metabolomes reveal enzymatic and transport processes at the interface of plasma and urine," published in 2023 in Nature Genetics
  • "Sequence Features of Mitochondrial Transporter Protein Families," published in 2020 in Biomolecules
  • "The N terminus of Orai1 couples to the AKAP79 signaling complex to drive NFAT1 activation by local Ca 2+ entry," published in 2021 in Proceedings of the National Academy of Sciences
  • "Oncogenic KRAS mutations enhance amino acid uptake by colorectal cancer cells via the hippo signaling effector YAP1," published in 2021 in Molecular Oncology

Matthias A. Hediger has collaborated frequently with several researchers, with whom they have coauthored numerous publications. The most frequent coauthors include:

  • Rajesh Bhardwaj (20 collaborations)
  • Gergely Gyimesi (18 collaborations)
  • Jonai Pujol-Giménez (18 collaborations)
  • Jean-Louis Reymond (12 collaborations)
  • Christine Peinelt (10 collaborations)

Best Publications

  • Cloning and characterization of a mammalian proton-coupled metal-ion transporter

    Hiromi Gunshin;Bryan Mackenzie;Urs V. Berger;Yoshimi Gunshin

  • Cloning and characterization of an extracellular Ca 2+ -sensing receptor from bovine parathyroid

    Edward M. Brown;Gerardo Gamba;Daniela Riccardi;Michael Lombardi

  • Knockout of Glutamate Transporters Reveals a Major Role for Astroglial Transport in Excitotoxicity and Clearance of Glutamate

    Jeffrey D Rothstein;Margaret Dykes-Hoberg;Carlos A Pardo;Lynn A Bristol

  • A Novel Duodenal Iron-Regulated Transporter, IREG1, Implicated in the Basolateral Transfer of Iron to the Circulation

    Andrew T McKie;Paola Marciani;Andreas Rolfs;Karen Brennan

  • Primary structure and functional characterization of a high-affinity glutamate transporter

    Yoshikatsu Kanai;Matthias A. Hediger;Matthias A. Hediger

  • An iron-regulated ferric reductase associated with the absorption of dietary iron

    Andrew T. McKie;Dalna Barrow;Gladys O. Latunde-Dada;Andreas Rolfs

  • Expression cloning and cDNA sequencing of the Na+/glucose co-transporter

    Matthias A. Hediger;Michael J. Coady;Tyson S. Ikeda;Ernest M. Wright

  • The ABCs of solute carriers: physiological, pathological and therapeutic implications of human membrane transport proteins

    Matthias A. Hediger;Michael F. Romero;Ji Bin Peng;Andreas Rolfs

  • Expression cloning of a mammalian proton-coupled oligopeptide transporter

    You Jun Fei;You Jun Fei;Yoshikatsu Kanai;Yoshikatsu Kanai;Stephan Nussberger;Vadivel Ganapathy

  • A family of mammalian Na + -dependent L -ascorbic acid transporters

    Hiroyasu Tsukaguchi;Taro Tokui;Bryan Mackenzie;Urs V. Berger

  • The human kidney low affinity Na+/glucose cotransporter SGLT2. Delineation of the major renal reabsorptive mechanism for D-glucose.

    Yoshikatsu Kanai;Wen Sen Lee;Guofeng You;Dennis Brown

  • Molecular Cloning and Characterization of a Channel-like Transporter Mediating Intestinal Calcium Absorption

    Ji-Bin Peng;Xing-Zhen Chen;Urs V. Berger;Peter M. Vassilev

  • Molecular cloning, primary structure, and characterization of two members of the mammalian electroneutral sodium-(potassium)-chloride cotransporter family expressed in kidney.

    Gerardo Gamba;Akihiko Miyanoshita;Michael Lombardi;Jonathan Lytton

  • Human Intestinal H+/Peptide Cotransporter: CLONING, FUNCTIONAL EXPRESSION, AND CHROMOSOMAL LOCALIZATION

    Rong Liang;You-Jun Fei;Puttur D. Prasad;Sammanda Ramamoorthy

  • The ABCs of membrane transporters in health and disease (SLC series): Introduction

    Matthias A. Hediger;Benjamin Clémençon;Robert E. Burrier;Elspeth A. Bruford

  • Molecular Characterization of a Broad Selectivity Neutral Solute Channel

    Hiroyasu Tsukaguchi;Chairat Shayakul;Urs V. Berger;Bryan Mackenzie

  • A Call for Systematic Research on Solute Carriers

    Adrián César-Razquin;Berend Snijder;Tristan Frappier-Brinton;Ruth Isserlin

  • Molecular physiology of sodium-glucose cotransporters.

    Matthias A. Hediger;David B. Rhoads

  • Mutations in the Tight-Junction Gene Claudin 19 (CLDN19) Are Associated with Renal Magnesium Wasting, Renal Failure, and Severe Ocular Involvement

    Martin Konrad;André Schaller;Dominik Seelow;Amit V. Pandey

  • The glutamate/neutral amino acid transporter family SLC1: molecular, physiological and pharmacological aspects

    Yoshikatsu Kanai;Matthias A. Hediger

Frequent Co-Authors

Yoshikatsu Kanai
Yoshikatsu Kanai Osaka University
Wen Sen Lee
Wen Sen Lee Taipei Medical University
Edward M. Brown
Edward M. Brown University of Rochester Medical Center
Walter F. Boron
Walter F. Boron Case Western Reserve University
Jean-Louis Reymond
Jean-Louis Reymond University of Bern
Rebecca G. Wells
Rebecca G. Wells University of Pennsylvania
Dennis Brown
Dennis Brown Harvard University
Christoph Romanin
Christoph Romanin Johannes Kepler University of Linz
Michael R. Freeman
Michael R. Freeman Cedars-Sinai Medical Center

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