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Hans-Hilger Ropers

Hans-Hilger Ropers

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Genetics
Germany
2024
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Genetics and Molecular Biology
Germany
2024

D-Index & Metrics

Genetics

D-Index
110
Citations
40314
World Ranking
539
National Ranking
39

Medicine

D-Index
110
Citations
40531
World Ranking
5605
National Ranking
311

Research.com Recognitions

  • 2024 - Research.com Genetics in Germany Leader Award
  • 2024 - Research.com Genetics and Molecular Biology in Germany Leader Award
  • 2023 - Research.com Genetics in Germany Leader Award
  • 2002 - Royal Netherlands Academy of Arts and Sciences

Overview

Hans-Hilger Ropers is affiliated with the Max Planck Society in Germany and conducts research primarily in the field of Biochemistry, Genetics and Molecular Biology. Their work spans several specialized subfields, including Genetics, Molecular Biology, Clinical Biochemistry, Developmental and Educational Psychology, and Cellular and Molecular Neuroscience.

Their research topics are diverse but focused on genomic and molecular mechanisms, with particular attention given to:

  • Genomics and Rare Diseases
  • Genetics and Neurodevelopmental Disorders
  • Mitochondrial Function and Pathology
  • RNA Modifications and Cancer
  • Genomic Variations and Chromosomal Abnormalities
  • Metabolism and Genetic Disorders
  • Reading and Literacy Development

Publications by Hans-Hilger Ropers appear in a variety of scientific journals and venues, reflecting the interdisciplinary nature of their work. Frequent publication venues include:

  • Human Genetics and Genomics Advances
  • UNC Libraries
  • Nature Communications
  • Zeitschrift für Kinder- und Jugendpsychiatrie und Psychotherapie
  • Molecular Genetics & Genomic Medicine

Recent significant papers include:

  • "POLRMT mutations impair mitochondrial transcription causing neurological disease," 2021, Nature Communications
  • "A Novel Locus and Candidate Gene for Familial Developmental Dyslexia on Chromosome 4q," 2020, Zeitschrift für Kinder- und Jugendpsychiatrie und Psychotherapie
  • "Discovery of a neuromuscular syndrome caused by biallelic variants in ASCC3," 2021, Human Genetics and Genomics Advances
  • "Discovery of a neuromuscular syndrome caused by biallelic variants in ASCC3," 2022, Human Genetics and Genomics Advances
  • "Comprehensive genotype-phenotype correlation in AP-4 deficiency syndrome; Adding data from a large cohort of Iranian patients," 2020, Clinical Genetics

Hans-Hilger Ropers collaborates frequently with researchers such as Kimia Kahrizi, Hossein Najmabadi, Vera M. Kalscheuer, Divya Nair, and Dong Li, indicating active partnerships in their fields of study.

Throughout their career, Ropers has received recognition including membership in the Royal Netherlands Academy of Arts and Sciences awarded in 2002.

Best Publications

  • Abnormal behavior associated with a point mutation in the structural gene for monoamine oxidase A

    H. G. Brunner;M. Nelen;X. O. Breakefield;H. H. Ropers

  • Deep sequencing reveals 50 novel genes for recessive cognitive disorders

    Hossein Najmabadi;Hao Hu;Masoud Garshasbi;Tomasz Zemojtel

  • X-linked mental retardation and autism are associated with a mutation in the NLGN4 gene, a member of the neuroligin family.

    Frédéric Laumonnier;Frédérique Bonnet-Brilhault;Marie Gomot;Romuald Blanc

  • Localization of the gene for Cowden disease to chromosome 10q22-23

    M. R. Nelen;G. W. Padberg;E. A J Peeters;A. Y. Lin

  • X-linked mental retardation

    Hans-Hilger Ropers;Ben C. J. Hamel

  • A systematic, large-scale resequencing screen of X-chromosome coding exons in mental retardation.

    Patrick S Tarpey;Raffaella Smith;Erin Pleasance;Annabel Whibley

  • Mutations in GRIN2A and GRIN2B encoding regulatory subunits of NMDA receptors cause variable neurodevelopmental phenotypes.

    Sabine Endele;Georg Rosenberger;Kirsten Geider;Bernt Popp

  • Association between X-linked mixed deafness and mutations in the POU domain gene POU3F4

    Y. J. M. De Kok;S. M. Van Der Maarel;M. Bitner-Glindzicz;I. Huber

  • Genetics of Early Onset Cognitive Impairment

    Hans Hilger Ropers

  • Comparative genome hybridization suggests a role for NRXN1 and APBA2 in schizophrenia

    George Kirov;Dilihan Gumus;Wei Chen;Nadine Norton

  • Cloning of a gene that is rearranged in patients with choroideraemia.

    Frans P. M. Cremers;Dorien J. R. van de Pol;Liesbeth P. M. van Kerkhoff;Berend Wieringa

  • Positional cloning of the gene for X-linked retinitis pigmentosa 2

    U. Schwahn;S. Lenzner;J Dong;S. Feil

  • Autosomal dominant and recessive osteochondrodysplasias associated with the COL11A2 locus

    Miikka Vikkula;Edwin C.M Madman;Vincent C.H Lui;Natalia I Zhidkova

  • Mutations in the JARID1C gene, which is involved in transcriptional regulation and chromatin remodeling, cause X-linked mental retardation.

    Lars Riff Jensen;Marion Amende;Ulf Gurok;Bettina Moser

  • A new member of the IL-1 receptor family highly expressed in hippocampus and involved in X-linked mental retardation

    A. Carrie;L. Jun;T. Bienvenu;M.C. Vinet

  • Opitz G/BBB syndrome, a defect of midline development, is due to mutations in a new RING finger gene on Xp22

    Nandita A. Quaderi;Susann Schweiger;Karin Gaudenz;Brunella Franco

  • Mutations in ARHGEF6 , encoding a guanine nucleotide exchange factor for Rho GTPases, in patients with X-linked mental retardation

    K. Kutsche;H.G. Yntema;A. Brandt;I. Jantke

  • Male pseudohermaphroditism due to a homozygous missense mutation of the luteinizing hormone receptor gene

    J.M.J. Kremer;R. Kraaij;S.P.A. Toledo;M. Post

  • Mutations in the X-Linked Cyclin-Dependent Kinase–Like 5 (CDKL5/STK9) Gene Are Associated with Severe Neurodevelopmental Retardation

    Jiong Tao;Hilde Van Esch;M. Hagedorn-Greiwe;Kirsten Hoffmann

  • Disruption of the serine/threonine kinase 9 gene causes severe X-linked infantile spasms and mental retardation

    Vera M. Kalscheuer;Jiong Tao;Andrew Donnelly;Georgina Hollway

Frequent Co-Authors

Vera M. Kalscheuer
Vera M. Kalscheuer Max Planck Society
Andreas Tzschach
Andreas Tzschach University of Freiburg
Reinhard Ullmann
Reinhard Ullmann Max Planck Society
Hossein Najmabadi
Hossein Najmabadi University of Social Welfare and Rehabilitation Sciences
Kimia Kahrizi
Kimia Kahrizi University of Social Welfare and Rehabilitation Sciences
Jozef Gecz
Jozef Gecz University of Adelaide
Jamel Chelly
Jamel Chelly Institute of Genetics and Molecular and Cellular Biology
Andreas W. Kuss
Andreas W. Kuss University of Greifswald
Hans van Bokhoven
Hans van Bokhoven Radboud University
Thomas F. Wienker
Thomas F. Wienker Max Planck Society

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