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Microbiology

D-Index
51
Citations
9626
World Ranking
4325
National Ranking
1671

Overview

Jason K. Whitmire is affiliated with the University of North Carolina at Chapel Hill in the United States. Their research spans multiple areas within medicine, particularly focusing on immunology and microbiology. The main fields of study include medicine and immunology and microbiology, with significant contributions also in immunology, hepatology, epidemiology, molecular biology, and cardiology and cardiovascular medicine.

Their work covers diverse topics such as:

  • Immune Cell Function and Interaction
  • Hepatitis Viruses Studies and Epidemiology
  • Hepatitis C virus research
  • T-cell and B-cell Immunology
  • Hepatitis B Virus Studies
  • Viral Infections and Immunology Research
  • Cytomegalovirus and herpesvirus research

Notable recent publications by Whitmire include:

  • "Caspase-7 activates ASM to repair gasdermin and perforin pores," 2022, published in Nature
  • "Content and Performance of the MiniMUGA Genotyping Array: A New Tool To Improve Rigor and Reproducibility in Mouse Research," 2020, published in Genetics
  • "Gangliosides are essential endosomal receptors for quasi-enveloped and naked hepatitis A virus," 2020, published in Nature Microbiology
  • "Human T cells efficiently control RSV infection," 2023, published in JCI Insight
  • "T cells protect against hepatitis A virus infection and limit infection-induced liver injury," 2021, published in Journal of Hepatology

The scientist frequently collaborates with other researchers including:

  • Ichiro Misumi
  • Stanley M. Lemon
  • John M. Cullen
  • You Li
  • Anshuman Das

Their work is often published in venues such as:

  • UNC Libraries
  • Journal of Hepatology
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Journal of Virology
  • Journal of Clinical Investigation

Best Publications

  • Humoral immunity due to long-lived plasma cells

    Mark K Slifka;Rustom Antia;Jason K Whitmire;Rafi Ahmed

  • Interferon-γ acts directly on CD8+ T cells to increase their abundance during virus infection

    Jason K. Whitmire;Joyce T. Tan;J. Lindsay Whitton

  • 4-1BB Ligand, a Member of the TNF Family, Is Important for the Generation of Antiviral CD8 T Cell Responses

    Joyce T. Tan;Jason K. Whitmire;Rafi Ahmed;Thomas C. Pearson

  • Detection of Intracellular Cytokines by Flow Cytometry

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  • A Role for Perforin in Downregulating T-Cell Responses during Chronic Viral Infection

    Mehrdad Matloubian;M. Suresh;Alison Glass;Marisa Galvan

  • Conserved T Cell Receptor Repertoire in Primary and Memory CD8 T Cell Responses to an Acute Viral Infection

    David J.D. Sourdive;Kaja Murali-Krishna;John D. Altman;Allan J. Zajac

  • Role of CD28-B7 interactions in generation and maintenance of CD8 T cell memory

    M. Suresh;Jason K. Whitmire;Laurie E. Harrington;Christian P. Larsen

  • The Mouse Universal Genotyping Array: From Substrains to Subspecies

    Andrew P. Morgan;Chen Ping Fu;Chia Yu Kao;Catherine E. Welsh

  • Role of CD4 T Cell Help and Costimulation in CD8 T Cell Responses During Listeria monocytogenes Infection

    Devon J. Shedlock;Jason K. Whitmire;Joyce Tan;Andrew S. MacDonald

  • Costimulation in antiviral immunity: differential requirements for CD4+ and CD8+ T cell responses

    Jason K Whitmire;Rafi Ahmed

  • 4-1BB costimulation is required for protective anti-viral immunity after peptide vaccination.

    Joyce T. Tan;Jason K. Whitmire;Kaja Murali-Krishna;Rafi Ahmed

  • Requirement of B cells for generating CD4+ T cell memory.

    Jason K. Whitmire;Mary S. Asano;Susan M. Kaech;Surojit Sarkar

  • CD40-CD40 ligand costimulation is required for generating antiviral CD4 T cell responses but is dispensable for CD8 T cell responses.

    Jason K. Whitmire;Richard A. Flavell;Iqbal S. Grewal;Iqbal S. Grewal;Christian P. Larsen

  • Inflammasomes coordinate pyroptosis and natural killer cell cytotoxicity to clear infection by a ubiquitous environmental bacterium

    Vivien I. Maltez;Alan L. Tubbs;Kevin D. Cook;Youssef Aachoui

  • CD40 LIGAND-DEFICIENT MICE GENERATE A NORMAL PRIMARY CYTOTOXIC T-LYMPHOCYTE RESPONSE BUT A DEFECTIVE HUMORAL RESPONSE TO A VIRAL INFECTION

    Jason K. Whitmire;Mark K. Slifka;Iqbal S. Grewal;Richard A. Flavell

  • The depletion of NK cells prevents T cell exhaustion to efficiently control disseminating virus infection

    Kevin D. Cook;Jason K. Whitmire

  • Regulation of the hepatitis C virus RNA replicase by endogenous lipid peroxidation

    Daisuke Yamane;David R McGivern;Eliane Wauthier;MinKyung Yi

  • Long-Term CD4 Th1 and Th2 Memory following Acute Lymphocytic Choriomeningitis Virus Infection

    Jason K. Whitmire;Mary S. Asano;Kaja Murali-Krishna;M. Suresh

  • A specific role for B cells in the generation of CD8 T cell memory by recombinant Listeria monocytogenes.

    Hao Shen;Jason K. Whitmire;Xin Fan;Devon J. Shedlock

  • Obesity Expands a Distinct Population of T Cells in Adipose Tissue and Increases Vulnerability to Infection

    Ichiro Misumi;Joshua Starmer;Toru Uchimura;Melinda A. Beck

  • Platelets prevent IFN-α/β-induced lethal hemorrhage promoting CTL-dependent clearance of lymphocytic choriomeningitis virus

    Matteo Iannacone;Giovanni Sitia;Masanori Isogawa;Jason K. Whitmire

Frequent Co-Authors

Rafi Ahmed
Rafi Ahmed Emory University
J. Lindsay Whitton
J. Lindsay Whitton Scripps Research Institute
Stanley M. Lemon
Stanley M. Lemon University of North Carolina at Chapel Hill
M. Suresh
M. Suresh University of Wisconsin–Madison
Terry Magnuson
Terry Magnuson University of North Carolina at Chapel Hill
John D. Altman
John D. Altman Emory University
Christian P. Larsen
Christian P. Larsen Emory University
Mark K. Slifka
Mark K. Slifka Oregon National Primate Research Center
Fernando Pardo-Manuel de Villena
Fernando Pardo-Manuel de Villena University of North Carolina at Chapel Hill
Thomas C. Pearson
Thomas C. Pearson Emory University

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