World's Best Scientists 2026 revealed!

D-Index & Metrics

Immunology

D-Index
79
Citations
46842
World Ranking
1656
National Ranking
818

Research.com Recognitions

  • 2012 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

J. Lindsay Whitton is affiliated with the Scripps Research Institute in the United States. Their research spans key areas within biochemistry, genetics, and molecular biology as well as medicine. Whitton has contributed to multiple subfields including infectious diseases, genetics, molecular biology, epidemiology, and cell biology.

Their scientific work addresses several main topics, notably viral gastroenteritis research and epidemiology, RNA modifications and cancer, autophagy in disease and therapy, endoplasmic reticulum stress and disease, research related to SARS-CoV-2 and COVID-19, diabetes and associated disorders, and interferon and immune responses.

Whitton's recent published papers include the following:

  • A food-responsive switch modulates TFEB and autophagy, and determines susceptibility to coxsackievirus infection and pancreatitis, 2020, published in Autophagy
  • Hepatocytes trap and silence coxsackieviruses, protecting against systemic disease in mice, 2020, published in Communications Biology
  • Hepatocytes engulf and rapidly silence coxsackievirus, protecting the host against systemic viral pathology, 2020, published in The Journal of Immunology

Frequent collaborators in Whitton's research include Claudia T. Flynn, Taishi Kimura, Mehrdad Alirezaei, and Selma D. Garcia.

The venues in which Whitton's work has appeared most often are:

  • Autophagy
  • Communications Biology
  • The Journal of Immunology

In recognition of their contributions to science, Whitton was named a Fellow of the American Association for the Advancement of Science (AAAS) in 2012.

Best Publications

  • Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

    Daniel J. Klionsky;Amal Kamal Abdel-Aziz;Sara Abdelfatah;Mahmoud Abdellatif

  • Guidelines for the use and interpretation of assays for monitoring autophagy

    Daniel J. Klionsky;Fabio C. Abdalla;Hagai Abeliovich;Robert T. Abraham

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • Molecular Mimicry, Bystander Activation, or Viral Persistence: Infections and Autoimmune Disease

    Robert S. Fujinami;Matthias G. von Herrath;Urs Christen;J. Lindsay Whitton

  • Clinical implications of dysregulated cytokine production

    M K Slifka;J L Whitton

  • Functional avidity maturation of CD8 + T cells without selection of higher affinity TCR

    Mark K. Slifka;Mark K. Slifka;J. Lindsay Whitton

  • Interferon-γ acts directly on CD8+ T cells to increase their abundance during virus infection

    Jason K. Whitmire;Joyce T. Tan;J. Lindsay Whitton

  • CD4-deficient mice have reduced levels of memory cytotoxic T lymphocytes after immunization and show diminished resistance to subsequent virus challenge.

    M. G. Von Herrath;M. Yokoyama;J. Dockter;M. B. A. Oldstone

  • Rapid on/off cycling of cytokine production by virus-specific CD8 + T cells

    Mark K. Slifka;Fernando Rodriguez;J. Lindsay Whitton

  • NK Markers Are Expressed on a High Percentage of Virus-Specific CD8+ and CD4+ T Cells

    Mark K. Slifka;Robb R. Pagarigan;J. Lindsay Whitton

  • Host and virus determinants of picornavirus pathogenesis and tropism.

    J. Lindsay Whitton;Christopher T. Cornell;Ralph Feuer

  • Detection of Intracellular Cytokines by Flow Cytometry

    Unknown

  • Coxsackievirus B exits the host cell in shed microvesicles displaying autophagosomal markers.

    Scott M. Robinson;Ginger Tsueng;Jon Sin;Vrushali Mangale

  • The role of CD8+ T lymphocytes in coxsackievirus B3-induced myocarditis.

    A Henke;S Huber;A Stelzner;J L Whitton

  • Microorganisms and autoimmunity: making the barren field fertile?

    Matthias G von Herrath;Robert S Fujinami;J Lindsay Whitton

  • DNA immunization: ubiquitination of a viral protein enhances cytotoxic T-lymphocyte induction and antiviral protection but abrogates antibody induction

    Unknown

  • Erratum to: Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (Autophagy, 12, 1, 1-222, 10.1080/15548627.2015.1100356

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • Recombinant vaccinia virus-induced T-cell immunity: quantitation of the response to the virus vector and the foreign epitope.

    Laurie E. Harrington;Robbert van der Most;J. Lindsay Whitton;Rafi Ahmed

  • Cell Cycle Status Affects Coxsackievirus Replication, Persistence, and Reactivation In Vitro

    Ralph Feuer;Ignacio Mena;Robb Pagarigan;Mark K. Slifka

  • Activated and memory CD8+ T cells can be distinguished by their cytokine profiles and phenotypic markers.

    Mark K. Slifka;J. Lindsay Whitton

  • DNA Immunization with Minigenes: Low Frequency of Memory Cytotoxic T Lymphocytes and Inefficient Antiviral Protection Are Rectified by Ubiquitination

    Fernando Rodriguez;Ling Ling An;Stephanie Harkins;Jie Zhang

Frequent Co-Authors

Jason K. Whitmire
Jason K. Whitmire University of North Carolina at Chapel Hill
Mark K. Slifka
Mark K. Slifka Oregon National Primate Research Center
Robert S. Fujinami
Robert S. Fujinami University of Utah
Sergio Lavandero
Sergio Lavandero University of Chile
Michael B. A. Oldstone
Michael B. A. Oldstone Scripps Research Institute
Evelina Gatti
Evelina Gatti Aix-Marseille University
William B. Kiosses
William B. Kiosses La Jolla Institute For Allergy & Immunology
Roberta A. Gottlieb
Roberta A. Gottlieb Cedars-Sinai Medical Center
Kelly S. Doran
Kelly S. Doran University of Colorado Denver
Beth Levine
Beth Levine The University of Texas Southwestern Medical Center

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