World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
60
Citations
16755
World Ranking
11771
National Ranking
5061

Overview

William B. Kiosses is affiliated with the La Jolla Institute For Allergy & Immunology in the United States. Their research spans multiple fields within biomedical science, focusing extensively on immunology, molecular biology, genetics, and epidemiology.

The main domains of their scholarly output include Medicine, Immunology and Microbiology, and Biochemistry, Genetics and Molecular Biology. Within these broader fields, subfields like Immunology, Immunology and Allergy, Molecular Biology, Genetics, and Epidemiology feature prominently in their work.

The scientist has contributed to research on several key topics, including:

  • Cell Adhesion Molecules Research
  • Neutrophil, Myeloperoxidase and Oxidative Mechanisms
  • Immune cells in cancer
  • Immune Response and Inflammation
  • Atherosclerosis and Cardiovascular Diseases
  • Diabetes and associated disorders
  • Diabetes Management and Research

William B. Kiosses has authored papers in reputable and specialized venues. Frequent publication outlets include:

  • The Journal of Immunology
  • UNC Libraries
  • Journal of Allergy and Clinical Immunology
  • Frontiers in Immunology
  • bioRxiv (Cold Spring Harbor Laboratory)

Notable recent publications detail cutting-edge research findings. Selected papers include:

  • "Olfactory receptor 2 in vascular macrophages drives atherosclerosis by NLRP3-dependent IL-1 production," published in 2022 in Science
  • "Elongated neutrophil-derived structures are blood-borne microparticles formed by rolling neutrophils during sepsis," 2020, The Journal of Experimental Medicine
  • "Single cell transcriptomics and TCR reconstruction reveal CD4 T cell response to MHC-II-restricted APOB epitope in human cardiovascular disease," 2022, Nature Cardiovascular Research
  • "NET formation is a default epigenetic program controlled by PAD4 in apoptotic neutrophils," 2023, Science Advances
  • "Chronic ethanol induces a pro-inflammatory switch in interleukin-1β regulation of GABAergic signaling in the medial prefrontal cortex of male mice," 2023, Brain Behavior and Immunity

The scientist has collaborated notably with several researchers, demonstrating ongoing partnerships across projects. Frequent co-authors include:

  • Klaus Ley
  • Marco Orecchioni
  • Sergio Catz
  • Zbigniew Mikulski
  • Holger Winkels

Best Publications

  • Regulation of the small GTP‐binding protein Rho by cell adhesion and the cytoskeleton

    Xiang‐Dong Ren;William B. Kiosses;Martin Alexander Schwartz

  • A mechanosensory complex that mediates the endothelial cell response to fluid shear stress

    Eleni Tzima;Mohamad Irani-Tehrani;William Kiosses;Elizabetta Dejana

  • Integrins regulate Rac targeting by internalization of membrane domains.

    Miguel A. del Pozo;Miguel A. del Pozo;Nazilla B. Alderson;William B. Kiosses;Hui-Hsien Chiang

  • Focal adhesion kinase suppresses Rho activity to promote focal adhesion turnover

    Xiang-Dong Ren;William B. Kiosses;David J. Sieg;Carol A. Otey

  • Phospho-caveolin-1 mediates integrin-regulated membrane domain internalization

    Miguel A. del Pozo;Nagaraj Balasubramanian;Nazilla B. Alderson;William B. Kiosses

  • Binding of paxillin to α 4 integrins modifies integrin-dependent biological responses

    Shouchun Liu;Sheila M. Thomas;Darren G. Woodside;David M. Rose

  • Integrins regulate GTP-Rac localized effector interactions through dissociation of Rho-GDI

    Miguel Angel Del Pozo;William B. Kiosses;Nazilla B. Alderson;Nahum Meller

  • Activation of Rac1 by shear stress in endothelial cells mediates both cytoskeletal reorganization and effects on gene expression

    Eleni Tzima;Miguel Angel Del Pozo;William B. Kiosses;Samih A. Mohamed

  • TLR2 Is Constitutively Expressed within the Kidney and Participates in Ischemic Renal Injury through Both MyD88-Dependent and -Independent Pathways

    Alana A. Shigeoka;Todd D. Holscher;Andrew J. King;Frank W. Hall

  • A role for p21-activated kinase in endothelial cell migration.

    William B. Kiosses;R. Hugh Daniels;Carol Otey;Gary M. Bokoch

  • Rac recruits high-affinity integrin αvβ3 to lamellipodia in endothelial cell migration

    William B. Kiosses;Sanford J. Shattil;Nisar Pampori;Martin Alexander Schwartz

  • Short-term fasting induces profound neuronal autophagy

    Mehrdad Alirezaei;Christopher C. Kemball;Claudia T. Flynn;Malcolm R. Wood

  • Increased filamin binding to beta-integrin cytoplasmic domains inhibits cell migration.

    David A. Calderwood;Anna Huttenlocher;William B. Kiosses;David M. R Rose

  • Differential alphav integrin-mediated Ras-ERK signaling during two pathways of angiogenesis.

    John D. Hood;Ricardo Frausto;William B. Kiosses;Martin A. Schwartz

  • An alpha4 integrin-paxillin-Arf-GAP complex restricts Rac activation to the leading edge of migrating cells.

    Naoyuki Nishiya;William B. Kiosses;Jaewon Han;Mark H. Ginsberg

  • Effects of cell tension on the small GTPase Rac

    Akira Katsumi;Julie Milanini;William B. Kiosses;Miguel A. del Pozo

  • Increased endothelial expression of Toll-like receptor 2 at sites of disturbed blood flow exacerbates early atherogenic events

    Adam E. Mullick;Katrin Soldau;William B. Kiosses;Thomas A. Bell

  • Zizimin1, a novel Cdc42 activator, reveals a new GEF domain for Rho proteins.

    Nahum Meller;Mohammad Irani-Tehrani;William B. Kiosses;Miguel A. Del Pozo

  • The relationship of autophagy defects to cartilage damage during joint aging in a mouse model.

    Beatriz Caramés;Merissa Olmer;William B. Kiosses;Martin K. Lotz

  • Coxsackievirus Infection Induces Autophagy-Like Vesicles and Megaphagosomes in Pancreatic Acinar Cells In Vivo

    Christopher C. Kemball;Mehrdad Alirezaei;Claudia T. Flynn;Malcolm R. Wood

Frequent Co-Authors

Martin A. Schwartz
Martin A. Schwartz Yale University
Lindsey A. Miles
Lindsey A. Miles Scripps Research Institute
Mark H. Ginsberg
Mark H. Ginsberg University of California, San Diego
J. Lindsay Whitton
J. Lindsay Whitton Scripps Research Institute
Nunzio Bottini
Nunzio Bottini University of California, San Diego
Martin Lotz
Martin Lotz Scripps Research Institute
Paul Schimmel
Paul Schimmel Scripps Research Institute
David L. Boyle
David L. Boyle University of California, San Diego
Shu Chien
Shu Chien University of California, San Diego
Howard S. Fox
Howard S. Fox University of Nebraska Medical Center

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