His main research concerns Cell biology, Signal transduction, Actin cytoskeleton, Endothelial stem cell and Immunology. His study of Cell adhesion molecule is a part of Cell biology. His work is dedicated to discovering how Signal transduction, Chemotaxis are connected with Video microscopy, Cell type, Activator and Enzyme activator and other disciplines.
His study looks at the intersection of Actin cytoskeleton and topics like Umbilical vein with Monolayer, Intracellular, Endoplasmic reticulum, Small GTPase and Actin. Peter L. Hordijk has included themes like Reactive oxygen species and Cell adhesion, VCAM-1 in his Endothelial stem cell study. His Immunology study incorporates themes from Interstitial tissue, Motility, Cell movement and Basement membrane.
Peter L. Hordijk mainly investigates Cell biology, Endothelial stem cell, Endothelium, RAC1 and GTPase. He has researched Cell biology in several fields, including Cell adhesion and Actin cytoskeleton, Cytoskeleton. His Endothelial stem cell research includes themes of CD34, Stromal cell, Homing and Cortactin.
The Endothelium study combines topics in areas such as Inflammation, Intercellular Adhesion Molecule-1, ICAM-1, Cell adhesion molecule and Monocyte. Peter L. Hordijk works mostly in the field of RAC1, limiting it down to topics relating to Guanine nucleotide exchange factor and, in certain cases, Pleckstrin homology domain, as a part of the same area of interest. His work focuses on many connections between Signal transduction and other disciplines, such as Chemotaxis, that overlap with his field of interest in Chemokine.
The scientist’s investigation covers issues in Cell biology, Endothelium, Endothelial stem cell, Inflammation and CDC42. His Cell biology research includes elements of Angiogenesis and Adherens junction. His research integrates issues of Proinflammatory cytokine, Ligand, CD40 and Antigen-presenting cell in his study of Endothelium.
His studies deal with areas such as Occludin, Chemokine, Protein phosphorylation, Cytoskeleton and Claudin as well as Endothelial stem cell. His Inflammation research is multidisciplinary, incorporating elements of Receptor, Extracellular matrix, Mechanotransduction and Cell type. His GTPase study combines topics from a wide range of disciplines, such as Cell division and Pleckstrin homology domain.
Cell biology, Endothelium, Endothelial stem cell, Inflammation and Heterotrimeric G protein are his primary areas of study. His work deals with themes such as Vasoconstriction and Cadherin, which intersect with Cell biology. Peter L. Hordijk interconnects Ephrin, Tyrosine phosphorylation, Erythropoietin-producing hepatocellular receptor and Leukocyte migration in the investigation of issues within Endothelium.
His Endothelial stem cell research incorporates themes from Chemokine, Receptor, Mechanotransduction, Vascular disease and Cell type. His Inflammation research is multidisciplinary, incorporating perspectives in Tumor necrosis factor alpha, Contractility, Anatomy and Endothelial dysfunction. His work deals with themes such as Molecular biology, Biophysics and Biosensor, which intersect with Heterotrimeric G protein.
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Breaching multiple barriers : Leukocyte motility through venular walls and the interstitium
Sussan Nourshargh;Peter L. Hordijk;Michael Sixt.
Nature Reviews Molecular Cell Biology (2010)
Regulation of NADPH Oxidases: The Role of Rac Proteins
Peter L. Hordijk.
Circulation Research (2006)
Inhibition of invasion of epithelial cells by Tiam1-Rac signaling.
Peter L. Hordijk;Jean Paul ten Klooster;Rob A. van der Kammen;Frits Michiels.
Pertussis toxin-sensitive activation of p21ras by G protein-coupled receptor agonists in fibroblasts
E J van Corven;P L Hordijk;R H Medema;J L Bos.
Proceedings of the National Academy of Sciences of the United States of America (1993)
Expression and localization of NOX2 and NOX4 in primary human endothelial cells
J.D. Van Buul;M. Fernandez-Borja;E.C. Anthony;P.L. Hordijk.
Antioxidants & Redox Signaling (2005)
Cleavage of CXCR1 on neutrophils disables bacterial killing in cystic fibrosis lung disease.
Dominik Hartl;Dominik Hartl;Philipp Latzin;Peter Hordijk;Veronica Marcos.
Nature Medicine (2007)
Reactive oxygen species mediate Rac-induced loss of cell-cell adhesion in primary human endothelial cells
Sandra van Wetering;Jaap D. van Buul;Safira Quik;Frederik P. J. Mul.
Journal of Cell Science (2002)
Molecular and functional interactions among monocytes, platelets, and endothelial cells and their relevance for cardiovascular diseases.
Janine M. van Gils;Jaap Jan Zwaginga;Jaap Jan Zwaginga;Peter L. Hordijk.
Journal of Leukocyte Biology (2009)
Regulated Membrane Localization of Tiam1, Mediated by the NH2-terminal Pleckstrin Homology Domain, Is Required for Rac-dependent Membrane Ruffling and C-Jun NH2-terminal Kinase Activation
Frits Michiels;Jord C. Stam;Peter L. Hordijk;Rob A. van der Kammen.
Journal of Cell Biology (1997)
Activation of Rhoa and ROCK are essential for detachment of migrating leukocytes.
Jacqueline Alblas;Laurien Ulfman;Peter Hordijk;Leo Koenderman.
Molecular Biology of the Cell (2001)
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