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Theodorus W. J. Gadella

Theodorus W. J. Gadella

D-Index & Metrics

Biology and Biochemistry

D-Index
61
Citations
14059
World Ranking
11301
National Ranking
292

Overview

Theodorus W. J. Gadella is affiliated with the University of Amsterdam in the Netherlands. Their research spans the fields of Biochemistry, Genetics and Molecular Biology, with a particular focus on Molecular Biology, Biophysics, Cell Biology, Bioengineering, and Materials Chemistry.

Their primary topics of work include advanced fluorescence microscopy techniques, advanced biosensing and bioanalysis techniques, bioluminescence and chemiluminescence research, receptor mechanisms and signaling, advanced biosensing techniques and applications, analytical chemistry and sensors, and studies related to biotin and related molecules.

Frequent publication venues for Gadella include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Methods
  • Journal of Cell Science
  • The Journal of Physical Chemistry B
  • Nature Communications

Selected recent papers authored by Gadella are:

  • mScarlet3: a brilliant and fast-maturing red fluorescent protein, 2023, Nature Methods
  • A turquoise fluorescence lifetime-based biosensor for quantitative imaging of intracellular calcium, 2021, Nature Communications
  • Visualizing endogenous Rho activity with an improved localization-based, genetically encoded biosensor, 2021, Journal of Cell Science
  • Multiparameter screening method for developing optimized red-fluorescent proteins, 2020, Nature Protocols
  • Single-cell imaging of ERK and Akt activation dynamics and heterogeneity induced by G-protein-coupled receptors, 2022, Journal of Cell Science

Gadella has collaborated frequently with several researchers, including:

  • Joachim Goedhart
  • Franka H. van der Linden
  • Laura van Weeren
  • Eike K. Mahlandt
  • Jaap D. van Buul

Best Publications

  • mScarlet: a bright monomeric red fluorescent protein for cellular imaging

    Daphne S Bindels;Lindsay Haarbosch;Laura van Weeren;Marten Postma

  • Structure-Guided Evolution of Cyan Fluorescent Proteins Towards a Quantum Yield of 93%

    Joachim Goedhart;David von Stetten;Marjolaine Noirclerc-Savoye;Marjolaine Noirclerc-Savoye;Mickaël Lelimousin

  • Bright monomeric red fluorescent protein with an extended fluorescence lifetime

    Ekaterina M Merzlyak;Joachim Goedhart;Dmitry Shcherbo;Mariya E Bulina

  • Cyan and yellow super fluorescent proteins with improved brightness, protein folding, and FRET Förster radius.

    Gert-Jan Kremers;Joachim Goedhart;Erik B. Van Munster;Theodorus W. J. Gadella

  • Controlled light-exposure microscopy reduces photobleaching and phototoxicity in fluorescence live-cell imaging

    R.A. Hoebe;C.H. van Oven;Th.W.J. Gadella;P.B. Dhonukshe;P.B. Dhonukshe

  • Fluorescence lifetime imaging microscopy (FLIM).

    Erik B van Munster;Theodorus W J Gadella

  • Bright cyan fluorescent protein variants identified by fluorescence lifetime screening

    Joachim Goedhart;Laura van Weeren;Mark A Hink;Norbert O E Vischer

  • HyPer-3: a genetically encoded H(2)O(2) probe with improved performance for ratiometric and fluorescence lifetime imaging.

    Dmitry S. Bilan;Luke Pase;Linda Joosen;Andrey Yu. Gorokhovatsky

  • Phospholipase D Activation Correlates with Microtubule Reorganization in Living Plant Cells

    Pankaj Dhonukshe;Ana M. Laxalt;Joachim Goedhart;Theodorus W. J. Gadella

  • Auxin transport inhibitors impair vesicle motility and actin cytoskeleton dynamics in diverse eukaryotes

    Pankaj Dhonukshe;Pankaj Dhonukshe;Pankaj Dhonukshe;Ilya Grigoriev;Rainer Fischer;Motoki Tominaga

  • Endocytosis of cell surface material mediates cell plate formation during plant cytokinesis.

    Pankaj Dhonukshe;Pankaj Dhonukshe;František Baluška;František Baluška;Markus Schlicht;Andrej Hlavacka

  • Analysis of MADS box protein-protein interactions in living plant cells.

    Richard G. H. Immink;Theodorus W. J. Gadella;Silvia Ferrario;Marco Busscher

  • An Orange Fluorescent Protein with a Large Stokes Shift for Single-Excitation Multicolor FCCS and FRET Imaging

    Daria M. Shcherbakova;Mark A. Hink;Linda Joosen;Theodorus W. J. Gadella

  • The Arabidopsis kinase-associated protein phosphatase controls internalization of the somatic embryogenesis receptor kinase 1

    Khalid Shah;Eugenia Russinova;Theodorus W.J. Gadella;Joost Willemse

  • Visualization of PtdIns3P dynamics in living plant cells

    Joop E.M. Vermeer;Wessel van Leeuwen;Rafa Tobeña-Santamaria;Ana M. Laxalt

  • A mTurquoise-Based cAMP Sensor for Both FLIM and Ratiometric Read-Out Has Improved Dynamic Range

    Jeffrey B. Klarenbeek;Joachim Goedhart;Mark A. Hink;Theodorus W. J. Gadella

  • Conformational changes in CLIP-170 regulate its binding to microtubules and dynactin localization

    Gideon Lansbergen;Yulia Komarova;Yulia Komarova;Mauro Modesti;Claire Wyman

  • Improved Green and Blue Fluorescent Proteins for Expression in Bacteria and Mammalian Cells

    Gert-Jan Kremers;Joachim Goedhart;Dave J. Van Den Heuvel;Hans C. Gerritsen

  • Visualization of phosphatidylinositol 4,5-bisphosphate in the plasma membrane of suspension-cultured tobacco BY-2 cells and whole Arabidopsis seedlings

    Wessel Van Leeuwen;Joop E.M. Vermeer;Theodorus W.J. Gadella;Teun Munnik

  • Alteration of Microtubule Dynamic Instability during Preprophase Band Formation Revealed by Yellow Fluorescent Protein–CLIP170 Microtubule Plus-End Labeling

    Pankaj Dhonukshe;Theodorus W. J. Gadella

Frequent Co-Authors

Antoine Royant
Antoine Royant Institut de Biologie Structurale
Carsten Schultz
Carsten Schultz Oregon Health & Science University
Kees Jalink
Kees Jalink Antoni van Leeuwenhoek Hospital
Peter L. Hordijk
Peter L. Hordijk University of Amsterdam
Teun Munnik
Teun Munnik University of Amsterdam
Ton Bisseling
Ton Bisseling Wageningen University & Research
Ben Scheres
Ben Scheres Wageningen University & Research
Jiří Friml
Jiří Friml Institute of Science and Technology Austria
Ikram Blilou
Ikram Blilou King Abdullah University of Science and Technology
Erik Nielsen
Erik Nielsen Northern Arizona University

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