His primary areas of study are Shigella flexneri, Secretion, Microbiology, Cell biology and Virulence. His Shigella flexneri research is multidisciplinary, incorporating elements of Extracellular, Cytoplasm and Transfection. His Secretion research incorporates themes from Shigella, Mutant and Effector.
His research investigates the link between Microbiology and topics such as Type three secretion system that cross with problems in Organelle, Membrane and Red blood cell. His Cell biology study incorporates themes from In vitro and Translocon. He combines subjects such as Plasmid, Operon and Enterobacteriaceae with his study of Virulence.
Claude Parsot mainly investigates Shigella flexneri, Secretion, Microbiology, Effector and Biochemistry. The various areas that he examines in his Shigella flexneri study include Molecular biology, Cytoplasm, Secretory protein and Chaperone. His study in Secretion is interdisciplinary in nature, drawing from both Intracellular parasite, Bacteria, Mutant, Enterobacteriaceae and Cell biology.
His work deals with themes such as Plasmid, Shigella, Type three secretion system, Virulence and Peptide sequence, which intersect with Microbiology. His Effector study combines topics from a wide range of disciplines, such as Plasma protein binding, Ubiquitin, Ubiquitin ligase, Coactivator and Innate immune system. His work in the fields of Biochemistry, such as Enzyme, Proteinase K, Gram-negative bacteria and Lysis, intersects with other areas such as Congo red.
Shigella flexneri, Secretion, Effector, Microbiology and Immune system are his primary areas of study. Shigella flexneri and Molecular biology are commonly linked in his work. Claude Parsot has included themes like Bacterial outer membrane, Cytoplasm and Intracellular parasite in his Secretion study.
His work carried out in the field of Effector brings together such families of science as Plasma protein binding, Ubiquitin, Ubiquitin ligase and Kinase activity. The concepts of his Microbiology study are interwoven with issues in Lymphocyte, Programmed cell death and Vacuole. In the subject of general Immune system, his work in Acquired immune system and Priming is often linked to B-1 cell, thereby combining diverse domains of study.
His primary areas of investigation include Secretion, Shigella flexneri, ATG8, Actin and Intracellular. His ATG8 research overlaps with other disciplines such as Vacuole, Bacterial outer membrane, Microbiology, RAB1 and Cytoplasm. In his research, Claude Parsot performs multidisciplinary study on Vacuole and Context.
The study incorporates disciplines such as Host cell cytoplasm, Green fluorescent protein, Intracellular parasite and Effector in addition to Actin.
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Nonpolar mutagenesis of the ipa genes defines IpaB, IpaC, and IpaD as effectors of Shigella flexneri entry into epithelial cells.
R Ménard;P J Sansonetti;C Parsot.
Journal of Bacteriology (1993)
The tripartite type III secreton of Shigella flexneri inserts IpaB and IpaC into host membranes.
Ariel Blocker;Pierre Gounon;Eric Larquet;Kirsten Niebuhr.
Journal of Cell Biology (1999)
The secretion of the Shigella flexneri Ipa invasins is activated by epithelial cells and controlled by IpaB and IpaD.
R. Ménard;P. Sansonetti;C. Parsot.
The EMBO Journal (1994)
Structure and composition of the Shigella flexneri "needle complex", a part of its type III secreton.
Ariel Blocker;Noureddine Jouihri;Eric Larquet;Pierre Gounon.
Molecular Microbiology (2001)
The virulence plasmid pWR100 and the repertoire of proteins secreted by the type III secretion apparatus of Shigella flexneri.
Carmen Buchrieser;Philippe Glaser;Christophe Rusniok;Hafed Nedjari.
Molecular Microbiology (2000)
An injected bacterial effector targets chromatin access for transcription factor NF-kappaB to alter transcription of host genes involved in immune responses.
Laurence Arbibe;Laurence Arbibe;Dong Wook Kim;Dong Wook Kim;Dong Wook Kim;Eric Batsche;Thierry Pedron;Thierry Pedron.
Nature Immunology (2007)
Extracellular association and cytoplasmic partitioning of the IpaB and IpaC invasins of S. flexneri
Robert Ménard;Philippe Sansonetti;Claude Parsot;Thierry Vasselon.
Conversion of PtdIns(4,5)P2 into PtdIns(5)P by the S.flexneri effector IpgD reorganizes host cell morphology
Kirsten Niebuhr;Sylvie Giuriato;Thierry Pedron;Dana J. Philpott.
The EMBO Journal (2002)
Optimization of virulence functions through glucosylation of Shigella LPS.
Nicholas P. West;Philippe Sansonetti;Joëlle Mounier;Rachel M. Exley.
The Shigella flexneri effector OspG interferes with innate immune responses by targeting ubiquitin-conjugating enzymes
Dong Wook Kim;Gerlinde Lenzen;Anne-Laure Page;Pierre Legrain.
Proceedings of the National Academy of Sciences of the United States of America (2005)
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