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Jorge E. Galán

Jorge E. Galán

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Microbiology
USA
2026

D-Index & Metrics

Microbiology

D-Index
118
Citations
51936
World Ranking
166
National Ranking
75

Research.com Recognitions

  • 2026 - Research.com Microbiology in United States Leader Award
  • 2025 - Research.com Microbiology in United States Leader Award

Overview

Jorge E. Galán is affiliated with Yale University in the United States. Their research encompasses various aspects of microbiology, molecular biology, and related fields, with a particular focus on bacterial pathogens.

Their recent publications include investigations into the interactions between Salmonella bacteria and host inflammatory responses. Notable papers authored or co-authored by Jorge E. Galán include:

  • Salmonella Typhimurium and inflammation: a pathogen-centric affair, 2021, Nature Reviews Microbiology
  • Itaconate is an effector of a Rab GTPase cell-autonomous host defense pathway against Salmonella, 2020, Science
  • The Salmonella effector protein SopD targets Rab8 to positively and negatively modulate the inflammatory response, 2021, Nature Microbiology
  • Parkinson's disease kinase LRRK2 coordinates a cell-intrinsic itaconate-dependent defence pathway against intracellular Salmonella, 2023, Nature Microbiology
  • Cryo-EM structure of the needle filament tip complex of the Salmonella type III secretion injectisome, 2021, Proceedings of the National Academy of Sciences

Jorge E. Galán collaborates frequently with several researchers, including:

  • María Lara-Tejero
  • Shu-Jung Chang
  • Eduardo Soto
  • Meixin Chen
  • Huan Lian

The primary publication venues for Jorge E. Galán's work include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Microbiology
  • Proceedings of the National Academy of Sciences
  • eLife
  • Nature Reviews Microbiology

Jorge E. Galán has also contributed to book publications, including a title published by Springer Science+Business Media:

  • Bacterial Type III Protein Secretion Systems, 2020

The main fields of study covered by Jorge E. Galán's research are:

  • Biochemistry, Genetics and Molecular Biology
  • Agricultural and Biological Sciences
  • Environmental Science

Within these broader fields, their work spans several subfields, such as:

  • Endocrinology
  • Food Science
  • Genetics
  • Ecology
  • Immunology

The scientist's main research topics include:

  • Salmonella and Campylobacter epidemiology
  • Bacterial Genetics and Biotechnology
  • Bacteriophages and microbial interactions
  • Vibrio bacteria research studies
  • Escherichia coli research studies
  • Endoplasmic Reticulum Stress and Disease
  • CRISPR and Genetic Engineering

Best Publications

  • IRAK-M is a negative regulator of toll-like receptor signaling

    Richard A. Flavell;Koichi Kobayashi;Ruslan M. Medzhitov

  • Type III Secretion Machines: Bacterial Devices for Protein Delivery into Host Cells

    Jorge E. Galán;Alan Collmer

  • Amplification of an invA gene sequence of Salmonella typhimurium by polymerase chain reaction as a specific method of detection of Salmonella.

    K. Rahn;S.A. De Grandis;R.C. Clarke;S.A. McEwen

  • Protein delivery into eukaryotic cells by type III secretion machines

    Jorge E. Galán;Hans Wolf-Watz

  • Supramolecular structure of the Salmonella typhimurium type III protein secretion system.

    Tomoko Kubori;Yukiyasu Matsushima;Yukiyasu Matsushima;Dai Nakamura;Dai Nakamura;Jaimol Uralil;Jaimol Uralil

  • Cloning and molecular characterization of genes whose products allow Salmonella typhimurium to penetrate tissue culture cells.

    J E Galán;rd R Curtiss

  • Critical role for NALP3/CIAS1/cryopyrin in innate and adaptive immunity through its regulation of caspase-1

    Fayyaz S. Sutterwala;Yasunori Ogura;Marian Szczepanik;Marian Szczepanik;Maria Lara-Tejero

  • RICK/Rip2/CARDIAK mediates signalling for receptors of the innate and adaptive immune systems

    Koichi Kobayashi;Naohiro Inohara;Lorraine D. Hernandez;Jorge E. Galán

  • S. typhimurium Encodes an Activator of Rho GTPases that Induces Membrane Ruffling and Nuclear Responses in Host Cells

    Wolf Dietrich Hardt;Li Mei Chen;Kornel E. Schuebel;Xosé R. Bustelo

  • Salmonella interactions with host cells: type III secretion at work.

    Jorge E. Galán

  • Molecular and functional characterization of the Salmonella invasion gene invA: homology of InvA to members of a new protein family.

    J E Galán;C Ginocchio;P Costeas

  • A Salmonella protein antagonizes Rac-1 and Cdc42 to mediate host-cell recovery after bacterial invasion

    Yixin Fu;Jorge E. Galán

  • A bacterial toxin that controls cell cycle progression as a deoxyribonuclease I-like protein.

    Maria Lara-Tejero;Jorge E. Galán

  • Molecular genetic bases of Salmonella entry into host cells

    Jorge E. Galán

  • Chaperone release and unfolding of substrates in type III secretion

    Yukihiro Akeda;Jorge E. Galán

  • Developmental Control of Endocytosis in Dendritic Cells by Cdc42

    Wendy S Garrett;Li-Mei Chen;Ruth Kroschewski;Ruth Kroschewski;Melanie Ebersold;Melanie Ebersold

  • Role of the S. typhimurium actin-binding protein SipA in bacterial internalization.

    Daoguo Zhou;Mark S. Mooseker;Jorge E. Galán

  • A Salmonella inositol polyphosphatase acts in conjunction with other bacterial effectors to promote host cell actin cytoskeleton rearrangements and bacterial internalization.

    Daoguo Zhou;Li-Mei Chen;Lorraine Hernandez;Stephen B. Shears

  • Bacterial type III secretion systems: specialized nanomachines for protein delivery into target cells

    Jorge E. Galán;Maria Lara-Tejero;Thomas C. Marlovits;Samuel Wagner

  • Salmonella spp. are cytotoxic for cultured macrophages

    Li Mei Chen;Koné Kaniga;Jorge E. Galán

Frequent Co-Authors

Jun Liu
Jun Liu Yale University
Richard A. Flavell
Richard A. Flavell Yale University
Gordon Dougan
Gordon Dougan University of Cambridge
James B. Bliska
James B. Bliska Dartmouth College
Ruben O. Donis
Ruben O. Donis University of Washington
Roy Curtiss
Roy Curtiss University of Florida
Stanley Falkow
Stanley Falkow Stanford University
Xi Chen
Xi Chen University of California, Davis
Fayyaz S. Sutterwala
Fayyaz S. Sutterwala Cedars-Sinai Medical Center

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