World's Best Scientists 2026 revealed!

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Biology and Biochemistry

D-Index
50
Citations
10035
World Ranking
17562
National Ranking
759

Overview

Olivier Bensaude is affiliated with the École Normale Supérieure in France. Their research primarily focuses on biochemistry, genetics, and molecular biology, with a strong emphasis on molecular biology. Their scientific work covers several interconnected subfields, including immunology, epidemiology, genetics, and cancer research.

The scientist's main topics of research include:

  • RNA Research and Splicing
  • RNA modifications and cancer
  • Herpesvirus Infections and Treatments
  • Toxin Mechanisms and Immunotoxins
  • RNA regulation and disease
  • CRISPR and Genetic Engineering
  • Interferon and immune responses

Recent papers authored or co-authored by Olivier Bensaude include:

  • "Structural and functional insights into CWC27/CWC22 heterodimer linking the exon junction complex to spliceosomes," published in 2020 in Nucleic Acids Research
  • "HSV-1 ICP22 Is a Selective Viral Repressor of Cellular RNA Polymerase II-Mediated Transcription Elongation," published in 2021 in Vaccines
  • "Exon-junction complex association with stalled ribosomes and slow translation-independent disassembly," published in 2024 in Nature Communications
  • "JMJD6 Regulates Splicing of Its Own Gene Resulting in Alternatively Spliced Isoforms with Different Nuclear Targets," published in 2020 in International Journal of Molecular Sciences
  • "HSV-1 ICP22 is a selective viral repressor of cellular RNA polymerase II-mediated transcription elongation," published in 2021 in bioRxiv (Cold Spring Harbor Laboratory)

The scientist's frequent co-authors include:

  • Hervé Le Hir
  • Nur Firdaus Isa
  • Nur Nadiah Che Aziz
  • Shona Murphy
  • Isabelle Barbosa

Olivier Bensaude's work has appeared repeatedly in respected venues, with frequent publications in:

  • Vaccines
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nucleic Acids Research
  • Nature Communications
  • BMC Molecular and Cell Biology

Best Publications

  • 7SK small nuclear RNA binds to and inhibits the activity of CDK9/cyclin T complexes

    Van Trung Nguyen;Tamás Kiss;Annemieke A. Michels;Olivier Bensaude

  • Heat shock proteins, first major products of zygotic gene activity in mouse embryo

    O. Bensaude;C. Babinet;M. Morange;F. Jacob

  • In vivo degradation of RNA polymerase II largest subunit triggered by alpha-amanitin.

    Van Trung Nguyen;Federico Giannoni;Marie-Françoise Dubois;Sook-Jae Seo

  • Investigating RNA polymerase II carboxyl-terminal domain (CTD) phosphorylation

    Benoît Palancade;Olivier Bensaude

  • Single-molecule tracking in live cells reveals distinct target-search strategies of transcription factors in the nucleus

    Ignacio Izeddin;Vincent Récamier;Lana Bosanac;Lana Bosanac;Ibrahim I Cissé

  • Binding of the 7SK snRNA turns the HEXIM1 protein into a P-TEFb (CDK9/cyclin T) inhibitor

    Annemieke A Michels;Alessandro Fraldi;Qintong Li;Todd E Adamson

  • LARP7 is a stable component of the 7SK snRNP while P-TEFb, HEXIM1 and hnRNP A1 are reversibly associated

    Brian J. Krueger;Célia Jeronimo;Bibhuti Bhusan Roy;Annie Bouchard

  • Growth-related changes in phosphorylation of yeast RNA polymerase II.

    Meera Patturajan;Roberta J. Schulte;Bartholomew M. Sefton;Ronald Berezney

  • MAQ1 and 7SK RNA Interact with CDK9/Cyclin T Complexes in a Transcription-Dependent Manner

    Annemieke A. Michels;Van Trung Nguyen;Alessandro Fraldi;Valérie Labas

  • The KIN28 Gene is Required both for RNA Polymerase II Mediated Transcription and Phosphorylation of the Rpb1p CTD

    Jean-Gabriel Valay;Michel Simon;Marie-Françoise Dubois;Olivier Bensaude

  • HSP70 AND HSP40 CHAPERONE ACTIVITIES IN THE CYTOPLASM AND THE NUCLEUS OF MAMMALIAN CELLS

    Annemieke A. Michels;Bart Kanon;Antonius W.T. Konings;Kenzo Ohtsuka

  • The hyperfluidization of mammalian cell membranes acts as a signal to initiate the heat shock protein response

    Gábor Balogh;Ibolya Horváth;Enikõ Nagy;Zsófia Hoyk

  • 7SK RNA, a non-coding RNA regulating P-TEFb, a general transcription factor.

    Gaelle Diribarne;Olivier Bensaude

  • A short region of its homeodomain is necessary for engrailed nuclear export and secretion.

    Alexis Maizel;Olivier Bensaude;Alain Prochiantz;Alain Joliot

  • The Transcriptional Inhibitors, Actinomycin D and α-Amanitin, Activate the HIV-1 Promoter and Favor Phosphorylation of the RNA Polymerase II C-terminal Domain

    Céline Cassé;Federico Giannoni;Van Trung Nguyen;Marie-Françoise Dubois

  • Nuclear translocation and carboxyl‐terminal domain phosphorylation of RNA polymerase II delineate the two phases of zygotic gene activation in mammalian embryos

    Sylvain Bellier;Sylvie Chastant;Sylvie Chastant;Pierre Adenot;Michel Vincent

  • Inhibition of HIV-1 replication by P-TEFb inhibitors DRB, seliciclib and flavopiridol correlates with release of free P-TEFb from the large, inactive form of the complex

    Sebastian Biglione;Sebastian Biglione;Sarah A Byers;Sarah A Byers;Jason P Price;Van Trung Nguyen

  • CTD serine-2 plays a critical role in splicing and termination factor recruitment to RNA polymerase II in vivo

    Bo Gu;Dirk Eick;Olivier Bensaude

  • The Nuclear Matrix Protein P255 Is a Highly Phosphorylated form of RNA Polymerase II Largest Subunit Which Associates With Spliceosomes

    Michel Vincent;Pascal Lauriault;Marie-Françoise Dubois;Sébastien Lavoie

  • The Transcription-Dependent Dissociation of P-TEFb-HEXIM1-7SK RNA Relies upon Formation of hnRNP-7SK RNA Complexes

    Charlotte Barrandon;François Bonnet;Van Trung Nguyen;Valérie Labas

Frequent Co-Authors

Xavier Darzacq
Xavier Darzacq University of California, Berkeley
Harm H. Kampinga
Harm H. Kampinga University Medical Center Groningen
David H. Price
David H. Price University of Iowa
László Vígh
László Vígh Hungarian Academy of Sciences
David P. Lane
David P. Lane Karolinska Institute
Bartholomew M. Sefton
Bartholomew M. Sefton Salk Institute for Biological Studies
Péter Csermely
Péter Csermely Semmelweis University
Alain Prochiantz
Alain Prochiantz Collège de France
Claude Kedinger
Claude Kedinger University of Strasbourg
Peter F. Stadler
Peter F. Stadler Leipzig University

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