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D-Index & Metrics

Molecular Biology

D-Index
101
Citations
35366
World Ranking
514
National Ranking
286

Research.com Recognitions

  • 2015 - Fellow of the American Academy of Arts and Sciences

Overview

Stewart Shuman is affiliated with the Memorial Sloan Kettering Cancer Center in the United States. Their research primarily falls within the domain of Biochemistry, Genetics, and Molecular Biology, with a significant focus on Molecular Biology. The body of work also spans Genetics, Cell Biology, Epidemiology, and Infectious Diseases.

The scientist's research topics cover various aspects of RNA and protein synthesis mechanisms,RNA modifications and cancer, fungal and yeast genetics research, RNA research and splicing, DNA repair mechanisms, bacterial genetics, and biotechnology, as well as biochemical and molecular research.

Frequent publication venues for their work include:

  • Nucleic Acids Research
  • RNA
  • mBio
  • Proceedings of the National Academy of Sciences
  • Journal of Biological Chemistry

Key frequent co-authors collaborating with Stewart Shuman include:

  • Beate Schwer
  • Ana M. Sánchez
  • Angad Garg
  • Shreya Ghosh
  • Garrett M. Warren

Representative recent publications authored or co-authored by Stewart Shuman include:

  • "Transcriptional interference at tandem lncRNA and protein-coding genes: an emerging theme in regulation of cellular nutrient homeostasis," 2020, Nucleic Acids Research
  • "A genetic screen for suppressors of hyper-repression of the fission yeast PHO regulon by Pol2 CTD mutation T4A implicates inositol 1-pyrophosphates as agonists of precocious lncRNA transcription termination," 2020, Nucleic Acids Research
  • "Cleavage-Polyadenylation Factor Cft1 and SPX Domain Proteins Are Agents of Inositol Pyrophosphate Toxicosis in Fission Yeast," 2022, mBio
  • "Activities and Structure-Function Analysis of Fission Yeast Inositol Pyrophosphate (IPP) Kinase-Pyrophosphatase Asp1 and Its Impact on Regulation of pho1 Gene Expression," 2022, mBio
  • "Genetic screen for suppression of transcriptional interference identifies a gain-of-function mutation in Pol2 termination factor Seb1," 2021, Proceedings of the National Academy of Sciences

In 2015, Stewart Shuman was recognized as a Fellow of the American Academy of Arts and Sciences.

Best Publications

  • Identification of microRNAs of the herpesvirus family

    Sébastien Pfeffer;Alain Sewer;Mariana Lagos-Quintana;Robert Sheridan

  • 5′-Capping enzymes are targeted to pre-mRNA by binding to the phosphorylated carboxy-terminal domain of RNA polymerase II

    Susan McCracken;Nova Fong;Emanuel Rosonina;Krassimir Yankulov

  • Structure-function analysis of STING activation by c[G(2',5')pA(3',5')p] and targeting by antiviral DMXAA.

    Pu Gao;Manuel Ascano;Thomas Zillinger;Weiyi Wang

  • Dynamic association of capping enzymes with transcribing RNA polymerase II

    Stephanie C. Schroeder;Beate Schwer;Stewart Shuman;David Bentley

  • What messenger RNA capping tells us about eukaryotic evolution

    Stewart Shuman

  • Structure, mechanism, and evolution of the mRNA capping apparatus.

    Stewart Shuman

  • Distinct Roles for CTD Ser-2 and Ser-5 Phosphorylation in the Recruitment and Allosteric Activation of Mammalian mRNA Capping Enzyme

    C.Kiong Ho;Stewart Shuman

  • Friction and torque govern the relaxation of DNA supercoils by eukaryotic topoisomerase IB

    Daniel A. Koster;Vincent Croquette;Cees Dekker;Stewart Shuman

  • Active Disruption of an RNA-Protein Interaction by a DExH/D RNA Helicase

    Eckhard Jankowsky;Christian H. Gross;Stewart Shuman;Anna Marie Pyle;Anna Marie Pyle

  • Conservation of Structure and Mechanism between Eukaryotic Topoisomerase I and Site-Specific Recombinases

    Chonghui Cheng;Paul Kussie;Nikola Pavletich;Stewart Shuman

  • Novel approach to molecular cloning and polynucleotide synthesis using vaccinia DNA topoisomerase.

    S Shuman

  • Bacterial DNA repair by non-homologous end joining.

    Stewart Shuman;Michael S Glickman

  • RNA capping enzyme and DNA ligase: a superfamily of covalent nucleotidyl transferases.

    Stewart Shuman;Beate Schwer

  • X-Ray Crystallography Reveals a Large Conformational Change during Guanyl Transfer by mRNA Capping Enzymes

    Kjell Håkansson;Aidan J. Doherty;Stewart Shuman;Dale B. Wigley

  • Structure of an mRNA capping enzyme bound to the phosphorylated carboxy-terminal domain of RNA polymerase II.

    Carme Fabrega;Vincent Shen;Stewart Shuman;Christopher D. Lima

  • Capping Enzyme in Eukaryotic mRNA Synthesis

    Stewart Shuman

  • The DExH protein NPH-II is a processive and directional motor for unwinding RNA.

    Eckhard Jankowsky;Christian H. Gross;Stewart Shuman;Anna Marie Pyle;Anna Marie Pyle

  • Crucial role for DNA ligase III in mitochondria but not in Xrcc1-dependent repair

    Deniz Simsek;Deniz Simsek;Amy Furda;Yankun Gao;Jérôme Artus

  • Mechanism of nonhomologous end-joining in mycobacteria: a low-fidelity repair system driven by Ku, ligase D and ligase C.

    Chunling Gong;Paola Bongiorno;Paola Bongiorno;Alexandra Martins;Alexandra Martins;Nicolas C Stephanou;Nicolas C Stephanou

  • Site-specific ribonuclease activity of eukaryotic DNA topoisomerase I.

    Jo Ann Sekiguchi;Stewart Shuman

Frequent Co-Authors

Beate Schwer
Beate Schwer Cornell University
Taha Merghoub
Taha Merghoub Cornell University
Jedd D. Wolchok
Jedd D. Wolchok Cornell University
Christopher D. Lima
Christopher D. Lima Memorial Sloan Kettering Cancer Center
Michael S. Glickman
Michael S. Glickman Memorial Sloan Kettering Cancer Center
Masad J. Damha
Masad J. Damha McGill University
Thomas Tuschl
Thomas Tuschl Rockefeller University
Sidney M. Hecht
Sidney M. Hecht Arizona State University
David Bentley
David Bentley University of Colorado Denver
Anna Marie Pyle
Anna Marie Pyle Yale University

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