2015 - Fellow of the American Academy of Arts and Sciences
His main research concerns Biochemistry, DNA, Molecular biology, RNA and DNA ligase. His studies in RNA triphosphatase, Capping enzyme, Guanylyltransferase, Binding site and RNA capping are all subfields of Biochemistry research. Stewart Shuman combines subjects such as Enzyme and Five-prime cap with his study of RNA triphosphatase.
His DNA research is multidisciplinary, relying on both Mycobacterium smegmatis, Phosphodiester bond and Active site. His Molecular biology research integrates issues from Recombinant DNA, Saccharomyces cerevisiae, In vitro recombination, Methyltransferase and Cell biology. His DNA ligase study integrates concerns from other disciplines, such as DNA repair and DNA replication.
Stewart Shuman mainly focuses on Biochemistry, RNA, DNA, Molecular biology and DNA ligase. His Biochemistry study focuses mostly on RNA triphosphatase, Active site, Capping enzyme, Enzyme and Guanylyltransferase. His studies deal with areas such as Triphosphatase and Messenger RNA as well as RNA triphosphatase.
His study in DNA is interdisciplinary in nature, drawing from both Phosphodiester bond, Cleavage and Stereochemistry. His work carried out in the field of Molecular biology brings together such families of science as Saccharomyces cerevisiae, Cell biology, RNA polymerase II, Transcription and Binding site. The DNA ligase study combines topics in areas such as Non-homologous end joining, DNA clamp, Polymerase and DNA polymerase.
The scientist’s investigation covers issues in Biochemistry, RNA, DNA, Cell biology and Vaccinia. His work on Biochemistry deals in particular with DNA ligase, Polynucleotide Kinase, Transferase, Amino acid and RNA capping. His RNA research is multidisciplinary, incorporating elements of Phosphotransferase and NAD+ kinase.
His DNA study combines topics from a wide range of disciplines, such as Molecular biology, Phosphodiester bond and Nucleic acid. His biological study spans a wide range of topics, including Polymerase and DNA polymerase I. His Cell biology study combines topics in areas such as Schizosaccharomyces pombe, Synthetic lethality, Messenger RNA, Transcription and Binding site.
Stewart Shuman focuses on Biochemistry, RNA, DNA, Gene and Transcription. In his works, Stewart Shuman conducts interdisciplinary research on Biochemistry and CTD. His DNA research incorporates themes from Molecular biology, Nucleic acid and Helicase.
As part of the same scientific family, Stewart Shuman usually focuses on Molecular biology, concentrating on Binding site and intersecting with DNA Mutational Analysis and Protein subunit. His Transcription study integrates concerns from other disciplines, such as Transcription factor, Gene expression and Cell biology. The study incorporates disciplines such as Phosphodiester bond and Ligase ribozyme in addition to DNA ligase.
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Identification of microRNAs of the herpesvirus family
Sébastien Pfeffer;Alain Sewer;Mariana Lagos-Quintana;Robert Sheridan.
Nature Methods (2005)
5′-Capping enzymes are targeted to pre-mRNA by binding to the phosphorylated carboxy-terminal domain of RNA polymerase II
Susan McCracken;Nova Fong;Emanuel Rosonina;Krassimir Yankulov.
Genes & Development (1997)
Dynamic association of capping enzymes with transcribing RNA polymerase II
Stephanie C. Schroeder;Beate Schwer;Stewart Shuman;David Bentley.
Genes & Development (2000)
Structure, mechanism, and evolution of the mRNA capping apparatus.
Progress in Nucleic Acid Research and Molecular Biology (2001)
What messenger RNA capping tells us about eukaryotic evolution
Nature Reviews Molecular Cell Biology (2002)
Structure-function analysis of STING activation by c[G(2',5')pA(3',5')p] and targeting by antiviral DMXAA.
Pu Gao;Manuel Ascano;Thomas Zillinger;Weiyi Wang.
Distinct Roles for CTD Ser-2 and Ser-5 Phosphorylation in the Recruitment and Allosteric Activation of Mammalian mRNA Capping Enzyme
C.Kiong Ho;Stewart Shuman.
Molecular Cell (1999)
Friction and torque govern the relaxation of DNA supercoils by eukaryotic topoisomerase IB
Daniel A. Koster;Vincent Croquette;Cees Dekker;Stewart Shuman.
Active Disruption of an RNA-Protein Interaction by a DExH/D RNA Helicase
Eckhard Jankowsky;Christian H. Gross;Stewart Shuman;Anna Marie Pyle;Anna Marie Pyle.
Conservation of Structure and Mechanism between Eukaryotic Topoisomerase I and Site-Specific Recombinases
Chonghui Cheng;Paul Kussie;Nikola Pavletich;Stewart Shuman.
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