World's Best Scientists 2026 revealed!

D-Index & Metrics

Immunology

D-Index
106
Citations
37262
World Ranking
570
National Ranking
340

Medicine

D-Index
107
Citations
37733
World Ranking
6315
National Ranking
3365

Research.com Recognitions

  • 1991 - Fellow of John Simon Guggenheim Memorial Foundation

Overview

Mark I. Greene is affiliated with the University of Pennsylvania in the United States and has contributed to research primarily in the fields of Medicine, Immunology and Microbiology, and Biochemistry, Genetics and Molecular Biology. Their work encompasses a range of subfields including Immunology, Oncology, Molecular Biology, Pulmonary and Respiratory Medicine, and Surgery.

Their research topics focus on several key areas such as:

  • Immune Cell Function and Interaction
  • T-cell and B-cell Immunology
  • IL-33, ST2, and ILC Pathways
  • HER2/EGFR in Cancer Research
  • Lung Cancer Treatments and Mutations
  • Cell death mechanisms and regulation
  • Cancer-related gene regulation

Recent publications by Mark I. Greene include:

  • "Regulatory T Cells: Regulation of Identity and Function," 2021, published in Frontiers in Immunology
  • "Th1 cytokine interferon gamma improves response in HER2 breast cancer by modulating the ubiquitin proteasomal pathway," 2021, published in Molecular Therapy
  • "PRMT5 Is Required for T Cell Survival and Proliferation by Maintaining Cytokine Signaling," 2020, published in Frontiers in Immunology
  • "Structural Features and PF4 Functions that Occur in Heparin-Induced Thrombocytopenia (HIT) Complicated by COVID-19," 2020, published in Antibodies
  • "Intratumoral delivery of dendritic cells plus anti-HER2 therapy triggers both robust systemic antitumor immunity and complete regression in HER2 mammary carcinoma," 2022, published in Journal for ImmunoTherapy of Cancer

Mark I. Greene frequently publishes in the following venues:

  • Frontiers in Immunology
  • Infection Control and Hospital Epidemiology
  • Molecular Therapy
  • Cancers
  • Antibodies

The scientist has collaborated regularly with several co-authors, including:

  • Payal Grover
  • Peeyush N. Goel
  • Hongtao Zhang
  • Qiang Wang
  • Krithika N. Kodumudi

Mark I. Greene was awarded the title of Fellow of the John Simon Guggenheim Memorial Foundation in 1991.

Best Publications

  • The neu oncogene: an erb-B-related gene encoding a 185,000-Mr tumour antigen.

    Alan L. Schechter;David F. Stern;Lalitha Vaidyanathan;Stuart J. Decker

  • Deacetylase inhibition promotes the generation and function of regulatory T cells

    Ran Tao;Edwin F de Zoeten;Engin Özkaynak;Chunxia Chen

  • Smad3 and NFAT cooperate to induce Foxp3 expression through its enhancer

    Yukiko Tone;Keiji Furuuchi;Yoshitsugu Kojima;Mark L Tykocinski

  • ErbB receptors: from oncogenes to targeted cancer therapies

    Hongtao Zhang;Alan Berezov;Qiang Wang;Geng Zhang

  • The Therapeutic Effect of Anti-HER2/neu Antibody Depends on Both Innate and Adaptive Immunity

    Sae Gwang Park;Zhujun Jiang;Eric D. Mortenson;Liufu Deng

  • Bound water molecules and conformational stabilization help mediate an antigen-antibody association.

    T N Bhat;G A Bentley;G Boulot;M I Greene

  • p185neu Expression in Human Lung Adenocarcinomas Predicts Shortened Survival

    Jeffrey A. Kern;David A. Schwartz;Joanne E. Nordberg;David B. Weiner

  • A point mutation in the neu oncogene mimics ligand induction of receptor aggregation

    David B. Weiner;Jing Liu;Jeffrey A. Cohen;William V. Williams

  • Down-modulation of an oncogene protein product and reversion of the transformed phenotype by monoclonal antibodies.

    Jeffrey A. Drebin;Victoria C. Link;Victoria C. Link;David F. Stern;Robert A. Weinberg

  • Regulation of the Immune Response to Tumor Antigens I. Immunosuppressor Cells in Tumor-Bearing Hosts

    Shigeyoshi Fujimoto;Mark I. Greene;Alec H. Sehon

  • Developmental defects in Gorlin syndrome related to a putative tumor suppressor gene on chromosome 9.

    Mae R. Gailani;Sherri J. Bale;David J. Leffell;John J. DiGiovanna

  • Intermolecular association of the p185neu protein and EGF receptor modulates EGF receptor function

    Takuro Wada;Xiaolan Qian;Mark I. Greene

  • FOXP3 interactions with histone acetyltransferase and class II histone deacetylases are required for repression

    Bin Li;Arabinda Samanta;Xiaomin Song;Kathryn T. Iacono

  • Development of Foxp3+ Regulatory T Cells Is Driven by the c-Rel Enhanceosome

    Qingguo Ruan;Vasumathi Kameswaran;Yukiko Tone;Li Li

  • Synergistic interaction of p185c-neu and the EGF receptor leads to transformation of rodent fibroblasts

    Yasuo Kokai;Jeffrey N. Myers;Takuro Wada;Valerie I. Brown

  • CD147 immunoglobulin superfamily receptor function and role in pathology

    Kathryn T. Iacono;Amy L. Brown;Mark I. Greene;Sandra J. Saouaf

  • The Ubiquitin Ligase Stub1 Negatively Modulates Regulatory T Cell Suppressive Activity by Promoting Degradation of the Transcription Factor Foxp3

    Zuojia Chen;Joseph Barbi;Shurui Bu;Shurui Bu;Huang Yu Yang;Huang Yu Yang

  • Expression of the neu gene-encoded protein (P185neu) in human non-small cell carcinomas of the lung

    David B. Weiner;Joanne Nordberg;Robert Robinson;Peter C. Nowell

  • Impairment of antigen-presenting cell function by ultraviolet radiation.

    Mark Irwin Greene;Man Sun Sy;Margaret Kripke;Baruj Benacerraf

  • BRCA1 binds c-Myc and inhibits its transcriptional and transforming activity in cells

    Qiang Wang;Hongtao Zhang;Kiichi Kajino;Mark I Greene

  • Inhibition of tumor growth by a monoclonal antibody reactive with an oncogene-encoded tumor antigen

    Jeffrey A. Drebin;Victoria C. Link;Robert A. Weinberg;Mark I. Greene

Frequent Co-Authors

Ramachandran Murali
Ramachandran Murali Cedars-Sinai Medical Center
Hongtao Zhang
Hongtao Zhang University of Pennsylvania
David B. Weiner
David B. Weiner The Wistar Institute
William V. Williams
William V. Williams GlaxoSmithKline (United Kingdom)
Bin Li
Bin Li Shanghai Jiao Tong University
Baruj Benacerraf
Baruj Benacerraf Harvard University
Wayne W. Hancock
Wayne W. Hancock University of Pennsylvania
Alfred Nisonoff
Alfred Nisonoff Brandeis University
Ronald N. Germain
Ronald N. Germain National Institute of Allergy and Infectious Diseases
Bernard N. Fields
Bernard N. Fields Harvard University

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

Exploring Immunology can lead to diverse career paths, especially when combined with healthcare and nursing specializations. Many students pursue advanced nursing degrees to complement their immunology knowledge, preparing for roles in patient care and research.

For those interested in mental health, top programs like the best pmhnp programs online offer high clinical placement rates, providing valuable hands-on experience. Affordability is also crucial; students can find some of the cheapest pmhnp programs to balance quality education with cost-effectiveness.

Graduates with a Doctor of Nursing Practice (DNP) degree can expect competitive salaries, varying by location. Detailed insights on earnings are available at doctor of nursing practice salary.

For nurses aiming to specialize further, transition opportunities such as the fnp to acute care np bridge program provide a structured path to acute care nurse practitioner roles, enhancing career growth options within immunology-related health fields.

Best Scientists Citing Mark I. Greene

Trending Scientists