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Immunology

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113
Citations
45512
World Ranking
434
National Ranking
266

Medicine

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114
Citations
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World Ranking
4764
National Ranking
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Research.com Recognitions

  • 2011 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

David B. Weiner is affiliated with The Wistar Institute in the United States. Their research spans multiple domains within medicine, immunology and microbiology, and biochemistry, genetics, and molecular biology. They have contributed significantly to subfields including infectious diseases, immunology, molecular biology, oncology, and epidemiology.

Their recent scientific papers cover diverse topics in immunology and infectious diseases, with a focus on COVID-19 and vaccine development. Notable publications include:

  • Immunogenicity of a DNA vaccine candidate for COVID-19 (2020) published in Nature Communications
  • Safety and immunogenicity of INO-4800 DNA vaccine against SARS-CoV-2: A preliminary report of an open-label, Phase 1 clinical trial (2020) published in EClinicalMedicine
  • DNA vaccines: prime time is now (2020) published in Current Opinion in Immunology
  • Tumor-infiltrating mast cells are associated with resistance to anti-PD-1 therapy (2021) published in Nature Communications
  • Personalized neoantigen vaccine and pembrolizumab in advanced hepatocellular carcinoma: a phase 1/2 trial (2024) published in Nature Medicine

Their research interests prominently include SARS-CoV-2 and COVID-19 research, immunotherapy and immune responses, vaccines and immunoinformatics approaches, CAR-T cell therapy research, COVID-19 clinical research studies, monoclonal and polyclonal antibodies research, and RNA interference and gene delivery.

David B. Weiner frequently collaborates with other researchers in the field. Frequent co-authors include:

  • Ami Patel
  • Nicholas J. Tursi
  • Laurent Humeau
  • E. Gary
  • Kate E. Broderick

Their work is published regularly in journals and platforms such as Cancer Research, bioRxiv (Cold Spring Harbor Laboratory), The Journal of Immunology, Frontiers in Immunology, and Nature Communications.

David B. Weiner was recognized as a Fellow of the American Association for the Advancement of Science (AAAS) in 2011.

Best Publications

  • Antibody mediated in vivo delivery of small interfering RNAs via cell-surface receptors

    Erwei Song;Pengcheng Zhu;Sang Kyung Lee;Dipanjan Chowdhury

  • DNA vaccines: ready for prime time?

    Michele A. Kutzler;David B. Weiner

  • Gene inoculation generates immune responses against human immunodeficiency virus type 1.

    Bin Wang;Kenneth E. Ugen;Vasantha Srikantan;Michael G. Agadjanyan

  • Safety, efficacy, and immunogenicity of VGX-3100, a therapeutic synthetic DNA vaccine targeting human papillomavirus 16 and 18 E6 and E7 proteins for cervical intraepithelial neoplasia 2/3: a randomised, double-blind, placebo-controlled phase 2b trial.

    Cornelia L Trimble;Matthew P Morrow;Kimberly A Kraynyak;Xuefei Shen

  • Innate Lymphoid Cells Promote Anatomical Containment of Lymphoid-Resident Commensal Bacteria

    Gregory F. Sonnenberg;Laurel A. Monticelli;Theresa Alenghat;Thomas C. Fung

  • First Human Trial of a DNA-Based Vaccine for Treatment of Human Immunodeficiency Virus Type 1 Infection: Safety and Host Response

    Rob Roy MacGregor;Jean D. Boyer;Kenneth E. Ugen;Kim E. Lacy

  • Immunogenicity of a DNA vaccine candidate for COVID-19.

    Trevor R.F. Smith;Ami Patel;Stephanie Ramos;Dustin Elwood

  • p185neu Expression in Human Lung Adenocarcinomas Predicts Shortened Survival

    Jeffrey A. Kern;David A. Schwartz;Joanne E. Nordberg;David B. Weiner

  • A point mutation in the neu oncogene mimics ligand induction of receptor aggregation

    David B. Weiner;Jing Liu;Jeffrey A. Cohen;William V. Williams

  • Clinical Applications of DNA Vaccines: Current Progress

    Bernadette Ferraro;Matthew P. Morrow;Natalie A. Hutnick;Thomas H. Shin

  • Electroporation delivery of DNA vaccines: prospects for success

    Niranjan Y Sardesai;David B Weiner

  • Protection of chimpanzees from high-dose heterologous HIV-1 challenge by DNA vaccination.

    Jean D. Boyer;Kenneth E. Ugen;Bin Wang;Michael Agadjanyan

  • In vivo engineering of a cellular immune response by coadministration of IL-12 expression vector with a DNA immunogen.

    Jong J. Kim;Velpandi Ayyavoo;Mark L. Bagarazzi;Michael A. Chattergoon

  • Immunotherapy Against HPV16/18 Generates Potent TH1 and Cytotoxic Cellular Immune Responses

    Mark L. Bagarazzi;Jian Yan;Matthew P. Morrow;Xuefei Shen

  • Compositions and methods for delivery of genetic material

    David B. Weiner;William V. Williams;Bin Wang;Leslie R. Coney

  • DNA vaccination: antigen presentation and the induction of immunity.

    Devon J. Shedlock;David B. Weiner

  • Serum Vpr regulates productive infection and latency of human immunodeficiency virus type 1.

    David N. Levy;Yosef Refaeli;Rob Roy MacGregor;David B. Weiner

  • Expression of the neu gene-encoded protein (P185neu) in human non-small cell carcinomas of the lung

    David B. Weiner;Joanne Nordberg;Robert Robinson;Peter C. Nowell

  • HIV-1 Vpr suppresses immune activation and apoptosis through regulation of nuclear factor kappa B.

    Velpandi Ayyavoo;Artin Mahboubi;S. Mahalingam;R. Ramalingam;R. Ramalingam

  • Safety and immunogenicity of an anti-Middle East respiratory syndrome coronavirus DNA vaccine: a phase 1, open-label, single-arm, dose-escalation trial.

    Kayvon Modjarrad;Christine C. Roberts;Kristin T. Mills;Amy R. Castellano

  • Antigens produced in plants by infection with chimeric plant viruses immunize against rabies virus and HIV-1

    V. Yusibov;A. Modelska;K. Steplewski;M. Agadjanyan

Frequent Co-Authors

Karuppiah Muthumani
Karuppiah Muthumani The Wistar Institute
Jean D. Boyer
Jean D. Boyer Inovio Pharmaceuticals (United States)
William V. Williams
William V. Williams GlaxoSmithKline (United Kingdom)
Niranjan Y. Sardesai
Niranjan Y. Sardesai University of Pennsylvania
Kenneth E. Ugen
Kenneth E. Ugen University of South Florida
Mark I. Greene
Mark I. Greene University of Pennsylvania
Thomas Kieber-Emmons
Thomas Kieber-Emmons University of Arkansas for Medical Sciences
George N. Pavlakis
George N. Pavlakis Emory University
Mark G. Lewis
Mark G. Lewis Walter Reed Army Institute of Research
Gary Kobinger
Gary Kobinger The University of Texas Medical Branch at Galveston

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