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Immunology

D-Index
62
Citations
16331
World Ranking
3116
National Ranking
1460

Overview

Jean D. Boyer is affiliated with Inovio Pharmaceuticals in the United States and has a research career focused primarily on medicine and immunology and microbiology. Their work spans multiple subfields including infectious diseases, immunology, oncology, epidemiology, and biotechnology.

The main topics addressed in Boyer's research include SARS-CoV-2 and COVID-19 research, immunotherapy and immune responses, cancer immunotherapy and biomarkers, CAR-T cell therapy research, COVID-19 clinical research studies, SARS-CoV-2 detection and testing, and animal virus infections studies.

Recent notable publications by Boyer include the following:

  • "Immunogenicity of a DNA vaccine candidate for COVID-19" (2020) in Nature Communications
  • "Safety and immunogenicity of INO-4800 DNA vaccine against SARS-CoV-2: A preliminary report of an open-label, Phase 1 clinical trial" (2020) in EClinicalMedicine
  • "SARS-CoV-2 DNA Vaccine INO-4800 Induces Durable Immune Responses Capable of Being Boosted in a Phase 1 Open-Label Trial" (2022) in The Journal of Infectious Diseases
  • "A Phase 1 Trial Assessing the Safety and Tolerability of a Therapeutic DNA Vaccination Against HPV16 and HPV18 E6/E7 Oncogenes After Chemoradiation for Cervical Cancer" (2020) in International Journal of Radiation Oncology*Biology*Physics
  • "INO-4800 DNA vaccine induces neutralizing antibodies and T cell activity against global SARS-CoV-2 variants" (2021) in npj Vaccines

Frequent coauthors collaborating with Boyer include:

  • David B. Weiner
  • Matthew P. Morrow
  • Albert J. Sylvester
  • Laurent Humeau
  • Kimberly A. Kraynyak

Common publication venues for Boyer's work are:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Cancer Research
  • Nature Communications
  • npj Vaccines
  • Vaccines

Best Publications

  • Gene inoculation generates immune responses against human immunodeficiency virus type 1.

    Bin Wang;Kenneth E. Ugen;Vasantha Srikantan;Michael G. Agadjanyan

  • Safety, efficacy, and immunogenicity of VGX-3100, a therapeutic synthetic DNA vaccine targeting human papillomavirus 16 and 18 E6 and E7 proteins for cervical intraepithelial neoplasia 2/3: a randomised, double-blind, placebo-controlled phase 2b trial.

    Cornelia L Trimble;Matthew P Morrow;Kimberly A Kraynyak;Xuefei Shen

  • First Human Trial of a DNA-Based Vaccine for Treatment of Human Immunodeficiency Virus Type 1 Infection: Safety and Host Response

    Rob Roy MacGregor;Jean D. Boyer;Kenneth E. Ugen;Kim E. Lacy

  • Immunogenicity of a DNA vaccine candidate for COVID-19.

    Trevor R.F. Smith;Ami Patel;Stephanie Ramos;Dustin Elwood

  • Gene transfer in humans using a conditionally replicating lentiviral vector

    Bruce L. Levine;Laurent M. Humeau;Jean Boyer;Rob-Roy MacGregor

  • Protection of chimpanzees from high-dose heterologous HIV-1 challenge by DNA vaccination.

    Jean D. Boyer;Kenneth E. Ugen;Bin Wang;Michael Agadjanyan

  • In vivo engineering of a cellular immune response by coadministration of IL-12 expression vector with a DNA immunogen.

    Jong J. Kim;Velpandi Ayyavoo;Mark L. Bagarazzi;Michael A. Chattergoon

  • Immunotherapy Against HPV16/18 Generates Potent TH1 and Cytotoxic Cellular Immune Responses

    Mark L. Bagarazzi;Jian Yan;Matthew P. Morrow;Xuefei Shen

  • Safety and immunogenicity of an anti-Middle East respiratory syndrome coronavirus DNA vaccine: a phase 1, open-label, single-arm, dose-escalation trial.

    Kayvon Modjarrad;Christine C. Roberts;Kristin T. Mills;Amy R. Castellano

  • CD8 positive T cells influence antigen-specific immune responses through the expression of chemokines.

    Jong J. Kim;Liesl K. Nottingham;Jeong I. Sin;Anthony Tsai

  • Modulation of amplitude and direction of in vivo immune responses by co‐administration of cytokine gene expression cassettes with DNA immunogens

    Jong J. Kim;Neil N. Trivedi;Liesl K. Nottingham;Lake Morrison

  • Engineering of in vivo immune responses to DNA immunization via codelivery of costimulatory molecule genes

    Jong J. Kirn;Mark L. Bagarazzi;Neil Trivedi;Yin Hu

  • Specific immune induction following DNA-based immunization through in vivo transfection and activation of macrophages/antigen-presenting cells.

    Michael A. Chattergoon;Tara M. Robinson;Jean D. Boyer;David B. Weiner

  • Standardization of cytokine flow cytometry assays

    Holden T Maecker;Aline Rinfret;Patricia D'Souza;Janice Darden

  • Modulating the immune response to genetic immunization.

    Adam. D. Cohen;Jean D. Boyer;David B. Weiner

  • Safety and Immunogenicity of an Anti-Zika Virus DNA Vaccine - Preliminary Report.

    Pablo Tebas;Christine C. Roberts;Kar Muthumani;Emma L. Reuschel

  • Safety and Comparative Immunogenicity of an HIV-1 DNA Vaccine in Combination with Plasmid Interleukin 12 and Impact of Intramuscular Electroporation for Delivery

    Spyros A. Kalams;Scott D. Parker;Marnie Elizaga;Barbara Metch

  • Intramuscular therapeutic vaccination targeting HPV16 induces T cell responses that localize in mucosal lesions.

    Leonel Maldonado;Jessica E. Teague;Matthew P. Morrow;Iveta Jotova

  • Safety and immunogenicity of INO-4800 DNA vaccine against SARS-CoV-2: A preliminary report of an open-label, Phase 1 clinical trial.

    Pablo Tebas;Shu Ping Yang;Jean D. Boyer;Emma L. Reuschel

  • In Vivo Modulation of Vaccine-Induced Immune Responses toward a Th1 Phenotype Increases Potency and Vaccine Effectiveness in a Herpes Simplex Virus Type 2 Mouse Model

    Jeong-Im Sin;Jong J. Kim;Jean D. Boyer;Richard B. Ciccarelli

  • Coimmunization with an optimized IL-15 plasmid results in enhanced function and longevity of CD8 T cells that are partially independent of CD4 T cell help.

    Michele A. Kutzler;Tara M. Robinson;Michael A. Chattergoon;Daniel K. Choo

Frequent Co-Authors

David B. Weiner
David B. Weiner The Wistar Institute
Kenneth E. Ugen
Kenneth E. Ugen University of South Florida
Niranjan Y. Sardesai
Niranjan Y. Sardesai University of Pennsylvania
William V. Williams
William V. Williams GlaxoSmithKline (United Kingdom)
Pablo Tebas
Pablo Tebas University of Pennsylvania
George N. Pavlakis
George N. Pavlakis Emory University
Karuppiah Muthumani
Karuppiah Muthumani The Wistar Institute
Mark G. Lewis
Mark G. Lewis Walter Reed Army Institute of Research
Rob Roy MacGregor
Rob Roy MacGregor University of Pennsylvania
Carl H. June
Carl H. June University of Pennsylvania

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