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Genetics

D-Index
59
Citations
15545
World Ranking
3222
National Ranking
7

Overview

Shih-Feng Tsai is affiliated with the National Health Research Institutes in Taiwan. Their research spans multiple areas within medicine and biochemistry, genetics, and molecular biology. The scientist's work covers several subfields, including molecular biology, immunology, infectious diseases, genetics, and oncology.

The main topics addressed in Tsai's research include SARS-CoV-2 and COVID-19 research, T-cell and B-cell immunology, SARS-CoV-2 detection and testing, genomics and rare diseases, RNA and protein synthesis mechanisms, genetics and neurodevelopmental disorders, and RNA regulation and disease.

Tsai has published a number of papers in various peer-reviewed journals. Notable recent publications include:

  • Emergence and Persistent Dominance of SARS-CoV-2 Omicron BA.2.3.7 Variant, Taiwan (2023) in Emerging Infectious Diseases
  • A Clinical and Integrated Genetic Study of Isolated and Combined Dystonia in Taiwan (2022) in Journal of Molecular Diagnostics
  • HBV DNA Integration into Telomerase or MLL4 Genes and TERT Promoter Point Mutation as Three Independent Signatures in Subgrouping HBV-Related HCC with Distinct Features (2023) in Liver Cancer
  • EGFR Mutation-Harboring Lung Cancer Cells Produce CLEC11A with Endothelial Trophic and Tumor-Promoting Activities (2022) in Cancers
  • Artificial-Intelligence-Assisted Discovery of Genetic Factors for Precision Medicine of Antiplatelet Therapy in Diabetic Peripheral Artery Disease (2022) in Biomedicines

Tsai frequently publishes in journals such as the Journal of Molecular Diagnostics, bioRxiv (Cold Spring Harbor Laboratory), Emerging Infectious Diseases, Liver Cancer, and Biomedicines.

The scientist often collaborates with other researchers, including Yung-Feng Lin, Hui-Ying Weng, Chen-Chi Wu, Pei-Lung Chen, and Pei-Lan Shao.

Best Publications

  • Erythroid differentiation in chimaeric mice blocked by a targeted mutation in the gene for transcription factor GATA-1

    Larysa Pevny;M. Celeste Simon;Elizabeth Robertson;William H. Klein

  • Cloning of cDNA for the major DNA-binding protein of the erythroid lineage through expression in mammalian cells

    Shih-Feng Tsai;David I. K. Martin;David I. K. Martin;Leonard I. Zon;Leonard I. Zon;Alan D. D'Andrea;Alan D. D'Andrea

  • High Frequency of Epidermal Growth Factor Receptor Mutations with Complex Patterns in Non–Small Cell Lung Cancers Related to Gefitinib Responsiveness in Taiwan

    Shiu Feng Huang;Hui Ping Liu;Ling Hui Li;Yuan Chieh Ku

  • Comparative Genome Analysis of Vibrio vulnificus, a Marine Pathogen

    Chung Yung Chen;Keh Ming Wu;Yo Cheng Chang;Chuan Hsiung Chang

  • HUMAN GATA-3 : A LINEAGE-RESTRICTED TRANSCRIPTION FACTOR THAT REGULATES THE EXPRESSION OF THE T CELL RECEPTOR ALPHA GENE

    I C Ho;P Vorhees;N Marin;B K Oakley

  • Functional analysis and in vivo footprinting implicate the erythroid transcription factor GATA-1 as a positive regulator of its own promoter.

    Shih-Feng Tsai;E. Strauss;S. H. Orkin

  • Mutation in the Tyrosine Kinase Domain of Epidermal Growth Factor Receptor Is a Predictive and Prognostic Factor for Gefitinib Treatment in Patients with Non–Small Cell Lung Cancer

    Teh-Ying Chou;Chao-Hua Chiu;Ling-Hui Li;Chun-Yen Hsiao

  • KEAP1 E3 Ligase-Mediated Downregulation of NF-κB Signaling by Targeting IKKβ

    Dung Fang Lee;Hsu Ping Kuo;Hsu Ping Kuo;Mo Liu;Mo Liu;Chao Kai Chou;Chao Kai Chou

  • Genome Sequencing and Comparative Analysis of Klebsiella pneumoniae NTUH-K2044, a Strain Causing Liver Abscess and Meningitis

    Keh-Ming Wu;Ling-Hui Li;Jing-Jou Yan;Nina Tsao;Nina Tsao

  • Increased γ-globin expression in a nondeletion HPFH mediated by an erythroid-specif ic DNA-binding factor

    David I. K. Martin;Shih-Feng Tsai;Stuart H. Orkin

  • Construction and analysis of a human-chimpanzee comparative clone map.

    Asao Fujiyama;Hidemi Watanabe;Atsushi Toyoda;Todd D. Taylor

  • Cisd2 deficiency drives premature aging and causes mitochondria-mediated defects in mice.

    Yi Fan Chen;Cheng Heng Kao;Ya Ting Chen;Ya Ting Chen;Chih Hao Wang

  • Sequencing and analysis of the large virulence plasmid pLVPK of Klebsiella pneumoniae CG43.

    Ying Tsong Chen;Hwan You Chang;Yi Chyi Lai;Chao Chi Pan

  • Type II Collagen Gene Variants and Inherited Osteonecrosis of the Femoral Head

    Yu Fen Liu;Wei Ming Chen;Yung Feng Lin;Ruei Cheng Yang

  • Genetic variants associated with phenytoin-related severe cutaneous adverse reactions

    Wen Hung Chung;Wen Hung Chung;Wan Chun Chang;Yun Shien Lee;Ying Ying Wu

  • Chromosomal changes and clonality relationship between primary and recurrent hepatocellular carcinoma

    Yann Jang Chen;Shiou Hwei Yeh;Jung Ta Chen;Cheng Chung Wu

  • Serum-Induced Iron-Acquisition Systems and TonB Contribute to Virulence in Klebsiella pneumoniae Causing Primary Pyogenic Liver Abscess

    Pei-Fang Hsieh;Tzu-Lung Lin;Cha-Ze Lee;Shih-Feng Tsai

  • DNA sequence and comparative analysis of chimpanzee chromosome 22.

    H. Watanabe;A. Fujiyama;M. Hattori;T. D. Taylor

  • Regulated expression of globin chains and the erythroid transcription factor GATA-1 during erythropoiesis in the developing mouse.

    E. Whitelaw;Shih-Feng Tsai;P. Hogben;S. H. Orkin

  • The major human erythroid DNA-binding protein (GF-1): primary sequence and localization of the gene to the X chromosome.

    Leonard I. Zon;Shih-Feng Tsai;Shawn Burgess;Paul Matsudaira

Frequent Co-Authors

Ih-Jen Su
Ih-Jen Su National Health Research Institutes
Stuart H. Orkin
Stuart H. Orkin Harvard University
Robert J. Desnick
Robert J. Desnick Icahn School of Medicine at Mount Sinai
Pei-Jer Chen
Pei-Jer Chen National Taiwan University
Chang-Phone Fung
Chang-Phone Fung Taipei Veterans General Hospital
Jin-Town Wang
Jin-Town Wang National Taiwan University
Shiou-Hwei Yeh
Shiou-Hwei Yeh National Taiwan University
Dung Fang Lee
Dung Fang Lee The University of Texas Health Science Center at Houston
Bernhard O. Palsson
Bernhard O. Palsson University of California, San Diego
Shan-Chwen Chang
Shan-Chwen Chang National Taiwan University

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