Dung Fang Lee

What is he best known for?

The fields of study he is best known for:

• Gene
• Cancer
• Transcription factor

His primary areas of study are Signal transduction, Cancer research, Cell biology, Downregulation and upregulation and Cell growth. In general Signal transduction, his work in PI3K/AKT/mTOR pathway and ErbB is often linked to ROR1 linking many areas of study. His Cancer research research is multidisciplinary, relying on both I-Kappa-B Kinase, Akt/PKB signaling pathway, CHUK, Hypertelorism and PTPN11.

His Cell biology research incorporates themes from Ubiquitin, Ubiquitin ligase, Carcinogenesis, Reprogramming and IκB kinase. His work focuses on many connections between Downregulation and upregulation and other disciplines, such as MAPK/ERK pathway, that overlap with his field of interest in Catenin, Oncogene, Beta-catenin and Transplantation. His studies deal with areas such as Receptor tyrosine kinase and Phosphorylation as well as Catenin.

His most cited work include:

• IκB Kinase Promotes Tumorigenesis through Inhibition of Forkhead FOXO3a (750 citations)
• Patient-specific induced pluripotent stem-cell-derived models of LEOPARD syndrome (584 citations)
• IKKβ Suppression of TSC1 Links Inflammation and Tumor Angiogenesis via the mTOR Pathway (511 citations)

What are the main themes of his work throughout his whole career to date?

Dung Fang Lee mainly focuses on Cancer research, Cell biology, Induced pluripotent stem cell, Signal transduction and Carcinogenesis. His biological study spans a wide range of topics, including Cancer, Metastasis, Cell growth, Downregulation and upregulation and Phosphorylation. His Downregulation and upregulation research is multidisciplinary, incorporating elements of Oncogene, Mdm2, Transplantation and MAPK/ERK pathway.

The concepts of his Cell biology study are interwoven with issues in Embryonic stem cell, Ubiquitin, IκB kinase and Homeobox protein NANOG. His work carried out in the field of Signal transduction brings together such families of science as Molecular biology, Kinase, Beta-Transducin Repeat-Containing Proteins and Transactivation. Dung Fang Lee interconnects Germline mutation, Wnt signaling pathway, Angiogenesis and GSK-3 in the investigation of issues within Carcinogenesis.

He most often published in these fields:

• Cancer research (72.97%)
• Cell biology (46.85%)
• Induced pluripotent stem cell (28.83%)

What were the highlights of his more recent work (between 2015-2021)?

• Cancer research (72.97%)
• Induced pluripotent stem cell (28.83%)
• Cell biology (46.85%)

In recent papers he was focusing on the following fields of study:

Cancer research, Induced pluripotent stem cell, Cell biology, Cancer and Osteosarcoma are his primary areas of study. His Cancer research study integrates concerns from other disciplines, such as Germline mutation, Carcinogenesis, Transcriptome, Metastasis and Notch signaling pathway. The Induced pluripotent stem cell study combines topics in areas such as Angiogenesis, Disease, Pathogenesis and Li–Fraumeni syndrome.

His Cell biology study combines topics from a wide range of disciplines, such as Mutation, Embryonic stem cell, Oxidative phosphorylation and Germ layer. His Cancer research includes elements of Genome editing, Reprogramming, Cellular differentiation and Bioinformatics. In his research, Mitochondrion and Downregulation and upregulation is intimately related to Pediatric cancer, which falls under the overarching field of Mesenchymal stem cell.

Between 2015 and 2021, his most popular works were:

• Osteosarcoma: Molecular Pathogenesis and iPSC Modeling (57 citations)
• MiR-26a inhibits stem cell-like phenotype and tumor growth of osteosarcoma by targeting Jagged1. (47 citations)
• AKT1 inhibits epithelial-to-mesenchymal transition in breast cancer through phosphorylation-dependent Twist1 degradation (45 citations)

In his most recent research, the most cited papers focused on:

• Gene
• Cancer
• Transcription factor

Dung Fang Lee spends much of his time researching Induced pluripotent stem cell, Cancer research, Bioinformatics, Stem cell and Genome editing. Dung Fang Lee combines subjects such as Cancer, Cancer Etiology, Pathogenesis and Human disease, Disease with his study of Induced pluripotent stem cell. His work on Osteosarcoma as part of general Cancer research study is frequently linked to AKT2, therefore connecting diverse disciplines of science.

Dung Fang Lee interconnects Intrahepatic Cholangiocarcinoma, Genomic profiling, Advanced stage, Cause of death and Liver cancer in the investigation of issues within Bioinformatics. His Stem cell research is multidisciplinary, incorporating perspectives in DNA-binding protein, Transcription factor, Zinc finger, Chromatin and Molecular biology. Dung Fang Lee focuses mostly in the field of Genome editing, narrowing it down to topics relating to Cellular differentiation and, in certain cases, Cell, Retinoblastoma, Cell biology, Cas9 and Germline.