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Thomas Arnesen

Thomas Arnesen

D-Index & Metrics

Molecular Biology

D-Index
50
Citations
9642
World Ranking
2567
National Ranking
9

Overview

Thomas Arnesen is affiliated with the University of Bergen in Norway. Their research primarily spans the fields of Biochemistry, Genetics and Molecular Biology, with significant contributions also in Medicine. Within these broad domains, their work focuses on several subfields including Molecular Biology, Oncology, Cancer Research, Surgery, and Cell Biology.

The main topics addressed in Arnesen's work include:

  • Peptidase Inhibition and Analysis
  • Ubiquitin and proteasome pathways
  • Signaling Pathways in Disease
  • Protease and Inhibitor Mechanisms
  • Pancreatic function and diabetes
  • Chemical Synthesis and Analysis
  • Glycosylation and Glycoproteins Research

Arnesen has published extensively in several key scientific venues. The most frequent publication forums include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Communications
  • Trends in Biochemical Sciences
  • Journal of Biological Chemistry
  • Methods in enzymology on CD-ROM/Methods in enzymology

Notable recent publications by Thomas Arnesen are:

  • N-terminal acetylation shields proteins from degradation and promotes age-dependent motility and longevity (2023, Nature Communications)
  • Mechanism of actin N-terminal acetylation (2020, Science Advances)
  • Mechanisms of Congenital Heart Disease Caused by NAA15 Haploinsufficiency (2021, Circulation Research)
  • Molecular basis for N-terminal acetylation by human NatE and its modulation by HYPK (2020, Nature Communications)
  • Biallelic NAA60 variants with impaired N-terminal acetylation capacity cause autosomal recessive primary familial brain calcifications (2024, Nature Communications)

Throughout their career, Arnesen has collaborated frequently with several co-authors, including:

  • Nina McTiernan
  • Rasmus Ree
  • Henriette Aksnes
  • Adrian Drazic
  • Sylvia Varland

Best Publications

  • The world of protein acetylation

    Adrian Drazic;Line M. Myklebust;Rasmus Ree;Thomas Arnesen;Thomas Arnesen

  • Proteomics analyses reveal the evolutionary conservation and divergence of N-terminal acetyltransferases from yeast and humans

    Thomas Arnesen;Petra Van Damme;Bogdan Polevoda;Kenny Helsens

  • Spotlight on protein N-terminal acetylation.

    Rasmus Ree;Sylvia Varland;Sylvia Varland;Thomas Arnesen;Thomas Arnesen

  • Protein N-terminal acetyltransferases: when the start matters

    Kristian K. Starheim;Kris Gevaert;Thomas Arnesen;Thomas Arnesen

  • Using VAAST to Identify an X-Linked Disorder Resulting in Lethality in Male Infants Due to N-Terminal Acetyltransferase Deficiency

    Alan F. Rope;Kai Wang;Rune Evjenth;Jinchuan Xing

  • Towards a functional understanding of protein N-terminal acetylation.

    Thomas Arnesen

  • Co-translational, Post-translational, and Non-catalytic Roles of N-Terminal Acetyltransferases.

    Henriette Aksnes;Rasmus Moen Ree;Thomas Arnesen;Thomas Arnesen

  • First Things First: Vital Protein Marks by N-Terminal Acetyltransferases

    Henriette Aksnes;Adrian Drazic;Michael Bruno Eric Marie;Thomas Arnesen;Thomas Arnesen

  • Identification and characterization of the human ARD1–NATH protein acetyltransferase complex

    Thomas Arnesen;Thomas Arnesen;Dave Anderson;Christian Baldersheim;Michel Lanotte

  • N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB

    Petra Van Damme;Marta Lasa;Bogdan Polevoda;Cristina Gazquez

  • NatF Contributes to an Evolutionary Shift in Protein N-Terminal Acetylation and Is Important for Normal Chromosome Segregation

    Petra Van Damme;Kristine Hole;Ana Pimenta-Marques;Kenny Helsens

  • N-terminal modifications of cellular proteins: The enzymes involved, their substrate specificities and biological effects.

    Sylvia Varland;Camilla Osberg;Camilla Osberg;Thomas Arnesen;Thomas Arnesen

  • Protein N-terminal acetyltransferases in cancer.

    T V Kalvik;T Arnesen;T Arnesen

  • NAA80 is actin’s N-terminal acetyltransferase and regulates cytoskeleton assembly and cell motility

    Adrian Drazic;Henriette Aksnes;Michaël Marie;Malgorzata Boczkowska

  • Molecular basis for N-terminal acetylation by the heterodimeric NatA complex

    Glen Liszczak;Glen Liszczak;Jacob M Goldberg;Håvard Foyn;E James Petersson

  • The Chaperone-Like Protein HYPK Acts Together with NatA in Cotranslational N-Terminal Acetylation and Prevention of Huntingtin Aggregation

    Thomas Arnesen;Thomas Arnesen;Kristian K. Starheim;Kristian K. Starheim;Petra Van Damme;Rune Evjenth

  • Proteome-derived Peptide Libraries Allow Detailed Analysis of the Substrate Specificities of Nα-acetyltransferases and Point to hNaa10p as the Post-translational Actin Nα-acetyltransferase

    Petra Van Damme;Rune Evjenth;Håvard Foyn;Håvard Foyn;Kimberly Demeyer

  • Knockdown of Human Nα-Terminal Acetyltransferase Complex C Leads to p53-Dependent Apoptosis and Aberrant Human Arl8b Localization

    Kristian K. Starheim;Kristian K. Starheim;Darina Gromyko;Darina Gromyko;Rune Evjenth;Anita Ryningen

  • A synopsis of eukaryotic Nα-terminal acetyltransferases: nomenclature, subunits and substrates

    Bogdan Polevoda;Thomas Arnesen;Thomas Arnesen;Fred Sherman

  • N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB

    P. Van Damme;M. Lasa;B. Polevoda;C. Gazquez

Frequent Co-Authors

Johan R. Lillehaug
Johan R. Lillehaug University of Bergen
Kris Gevaert
Kris Gevaert Ghent University
Petra Van Damme
Petra Van Damme Ghent University
Gholson J. Lyon
Gholson J. Lyon Cold Spring Harbor Laboratory
Ronen Marmorstein
Ronen Marmorstein University of Pennsylvania
Joël Vandekerckhove
Joël Vandekerckhove Ghent University
Mark Yandell
Mark Yandell University of Utah
Lynn B. Jorde
Lynn B. Jorde University of Utah
Leslie G. Biesecker
Leslie G. Biesecker National Institutes of Health
Hakon Hakonarson
Hakon Hakonarson Children's Hospital of Philadelphia

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