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Biology and Biochemistry

D-Index
67
Citations
12917
World Ranking
8371
National Ranking
612

Overview

Markus Wirtz is affiliated with Heidelberg University in Germany and has a significant body of work in fields intersecting biochemistry, genetics, and molecular biology, as well as agricultural and biological sciences. Their research contributions focus extensively on molecular biology and plant science, with additional involvement in oncology, renewable energy and environmental sustainability, and environmental chemistry.

The primary research topics covered in their publications include peptidase inhibition and analysis, ubiquitin and proteasome pathways, nitrogen and sulfur effects on Brassica, signaling pathways in disease, photosynthetic processes and mechanisms, plant stress responses and tolerance, and plant nutrient uptake and metabolism.

Frequent publication venues for their work are:

  • Nature Communications
  • PLANT PHYSIOLOGY
  • bioRxiv (Cold Spring Harbor Laboratory)
  • New Phytologist
  • The Plant Cell

Markus Wirtz has collaborated repeatedly with a group of co-authors, including:

  • Rüdiger Hell
  • Laura Armbruster
  • Eric Linster
  • Thierry Meinnel
  • Carmela Giglione

Recent publications illustrate the scope and focus of their work. These include:

  • A molecular switch in sulfur metabolism to reduce arsenic and enrich selenium in rice grain (2021, Nature Communications)
  • Dual lysine and N-terminal acetyltransferases reveal the complexity underpinning protein acetylation (2020, Molecular Systems Biology)
  • Cotranslational N-degron masking by acetylation promotes proteome stability in plants (2022, Nature Communications)
  • The Arabidopsis Nα-acetyltransferase NAA60 locates to the plasma membrane and is vital for the high salt stress response (2020, New Phytologist)
  • Mitochondrial alternative NADH dehydrogenases NDA1 and NDA2 promote survival of reoxygenation stress in Arabidopsis by safeguarding photosynthesis and limiting ROS generation (2022, New Phytologist)

Their contributions reflect attention to plant molecular responses to environmental stresses and biochemical mechanisms regulating protein modifications and stability. The work intersects analyses of metabolic pathways, stress tolerance, and photosynthetic mechanisms, contributing to a broader understanding of plant biology and molecular function.

Best Publications

  • Evidence for a SAL1-PAP Chloroplast Retrograde Pathway That Functions in Drought and High Light Signaling in Arabidopsis

    Gonzalo M. Estavillo;Peter A. Crisp;Wannarat Pornsiriwong;Markus Wirtz

  • The NADPH-dependent thioredoxin system constitutes a functional backup for cytosolic glutathione reductase in Arabidopsis.

    Laurent Marty;Wafi Siala;Markus Schwarzländer;Mark D. Fricker

  • Methionine salvage and S-adenosylmethionine: essential links between sulfur, ethylene and polyamine biosynthesis

    Margret Sauter;Barbara Moffatt;Maye Chin Saechao;Rüdiger Hell

  • The analysis of Arabidopsis nicotianamine synthase mutants reveals functions for nicotianamine in seed iron loading and iron deficiency responses

    Marco Klatte;Mara Schuler;Markus Wirtz;Claudia Fink-Straube

  • Vacuolar Nicotianamine Has Critical and Distinct Roles under Iron Deficiency and for Zinc Sequestration in Arabidopsis

    Michael J. Haydon;Michael J. Haydon;Miki Kawachi;Miki Kawachi;Markus Wirtz;Stefan Hillmer

  • Analysis of the Arabidopsis O-Acetylserine(thiol)lyase Gene Family Demonstrates Compartment-Specific Differences in the Regulation of Cysteine Synthesis

    Corinna Heeg;Cordula Kruse;Ricarda Jost;Michael Gutensohn

  • O-acetylserine (thiol) lyase: an enigmatic enzyme of plant cysteine biosynthesis revisited in Arabidopsis thaliana.

    Markus Wirtz;Michel Droux;Rüdiger Hell

  • Retrograde Plastid Redox Signals in the Expression of Nuclear Genes for Chloroplast Proteins of Arabidopsis thaliana

    Vidal Fey;Raik Wagner;Katharina Braütigam;Markus Wirtz

  • Functional analysis of the cysteine synthase protein complex from plants: Structural, biochemical and regulatory properties

    Markus Wirtz;Rüdiger Hell

  • Regulation of Sulfate Uptake and Expression of Sulfate Transporter Genes in Brassica oleracea as Affected by Atmospheric H2S and Pedospheric Sulfate Nutrition

    Peter Buchner;C. Elisabeth E. Stuiver;Sue Westerman;Markus Wirtz

  • Disruption of adenosine-5'-phosphosulfate kinase in Arabidopsis reduces levels of sulfated secondary metabolites

    Sarah G. Mugford;Naoko Yoshimoto;Michael Reichelt;Markus Wirtz

  • Balancing metabolites in drought: the sulfur assimilation conundrum

    Kai Xun Chan;Markus Wirtz;Su Yin Phua;Gonzalo M. Estavillo

  • Dynamic Plastid Redox Signals Integrate Gene Expression and Metabolism to Induce Distinct Metabolic States in Photosynthetic Acclimation in Arabidopsis

    Katharina Bräutigam;Lars Dietzel;Tatjana Kleine;Elke Ströher

  • SULTR3;1 is a chloroplast-localized sulfate transporter in Arabidopsis thaliana

    Min-Jie Cao;Zhen Wang;Markus Wirtz;Ruediger Hell

  • Restricting glutathione biosynthesis to the cytosol is sufficient for normal plant development.

    Maciej Pasternak;Benson Lim;Markus Wirtz;Riidiger Hell

  • Sulfite Reductase Defines a Newly Discovered Bottleneck for Assimilatory Sulfate Reduction and Is Essential for Growth and Development in Arabidopsis thaliana

    Muhammad Sayyar Khan;Florian Heinrich Haas;Arman Allboje Samami;Amin Moghaddas Gholami

  • Differential Regulation of the Expression of Two High-Affinity Sulfate Transporters, SULTR1.1 and SULTR1.2, in Arabidopsis

    Hatem Rouached;Markus Wirtz;Remi Alary;Rüdiger Hell

  • Integration of light and metabolic signals for stem cell activation at the shoot apical meristem

    Anne Pfeiffer;Denis Janocha;Yihan Dong;Anna Medzihradszky

  • Synthesis of the sulfur amino acids: cysteine and methionine

    Markus Wirtz;Michel Droux

  • The role of methionine recycling for ethylene synthesis in Arabidopsis

    Katharina Bürstenbinder;Guillaume Rzewuski;Markus Wirtz;Rüdiger Hell

Frequent Co-Authors

Rüdiger Hell
Rüdiger Hell Heidelberg University
Andreas J. Meyer
Andreas J. Meyer University of Bonn
Oliver Berkowitz
Oliver Berkowitz La Trobe University
Markus Schwarzländer
Markus Schwarzländer University of Münster
Janneke Balk
Janneke Balk John Innes Centre
Michael Reichelt
Michael Reichelt Max Planck Society
Thierry Meinnel
Thierry Meinnel University of Paris-Saclay
Stanislav Kopriva
Stanislav Kopriva University of Cologne
Margret Sauter
Margret Sauter Kiel University
Michela Schiavon
Michela Schiavon University of Padua

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