His scientific interests lie mostly in Proteoglycan, Biochemistry, Cell biology, Perlecan and Basement membrane. His biological study spans a wide range of topics, including Molecular biology, Biophysics and Glycosaminoglycan. His work on Laminin and Cell type as part of general Biochemistry research is frequently linked to Aggrecan, thereby connecting diverse disciplines of science.
His study in Cell biology is interdisciplinary in nature, drawing from both Immunohistochemistry, Neurofilament, Cartilage and Senile plaques. His Perlecan research is under the purview of Heparan sulfate. His biological study deals with issues like Extracellular matrix, which deal with fields such as Cell and Myocyte.
His primary areas of investigation include Biochemistry, Proteoglycan, Cell biology, Molecular biology and Perlecan. His Proteoglycan study incorporates themes from Biophysics and Peptide sequence. His Cell biology research includes themes of Chondrocyte, In vitro and Cartilage.
His Molecular biology research also works with subjects such as
Cell biology, Perlecan, Extracellular matrix, Biochemistry and Stromal cell are his primary areas of study. His Cell biology research incorporates themes from Cell growth, Wound healing, Receptor, Growth factor and Stimulation. His Perlecan research integrates issues from Chondrocyte, Chondroitin sulfate, Endochondral ossification and Endocrinology.
His Extracellular matrix research includes elements of Molecular biology, Agarose, Procollagen peptidase and In vitro. His Keratan sulfate study, which is part of a larger body of work in Biochemistry, is frequently linked to Proteoglycan synthesis, bridging the gap between disciplines. Keratan sulfate is a subfield of Proteoglycan that he tackles.
The scientist’s investigation covers issues in Cell biology, Extracellular matrix, Molecular biology, Wound healing and Perlecan. His Cell biology study incorporates themes from Receptor, Biochemistry and Cell growth. He works on Biochemistry which deals in particular with Lumican.
His research in Extracellular matrix intersects with topics in Procollagen peptidase and Basement membrane. As part of one scientific family, he deals mainly with the area of Perlecan, narrowing it down to issues related to the Chondrocyte, and often Chondroitin sulfate, Fibroblast growth factor, Immunoprecipitation and Heparan sulfate. His Keratocan study results in a more complete grasp of Proteoglycan.
This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.
Basement Membrane Complexes with Biological Activity
Hynda K. Kleinman;Mary L. McGarvey;John R. Hassell;Vicki L. Star.
Isolation of a heparan sulfate-containing proteoglycan from basement membrane
John R. Hassell;Pamela Gehron Robey;Hans-Jurgen Barrach;Joseph Wilczek.
Proceedings of the National Academy of Sciences of the United States of America (1980)
Perlecan is essential for cartilage and cephalic development
Eri Arikawa-Hirasawa;Hideto Watanabe;Hiroya Takami;John R. Hassell.
Nature Genetics (1999)
Influence of a reconstituted basement membrane and its components on casein gene expression and secretion in mouse mammary epithelial cells.
Ming Liang Li;Judith Aggeler;Deborah A. Farson;Carroll Hatier.
Proceedings of the National Academy of Sciences of the United States of America (1987)
The complete sequence of perlecan, a basement membrane heparan sulfate proteoglycan, reveals extensive similarity with laminin A chain, low density lipoprotein-receptor, and the neural cell adhesion molecule.
Douglas M. Noonan;Anna Fulle;Piera Valente;Silla Cai.
Journal of Biological Chemistry (1991)
Biological activities of laminin
Hynda K. Kleinman;Frances B. Cannon;Gordon W. Laurie;John R. Hassell.
Journal of Cellular Biochemistry (1985)
Proteoglycan core protein families.
John R. Hassell;James H. Kimura;Vincent C. Hascall.
Annual Review of Biochemistry (1986)
Complete primary structure of the rat cartilage proteoglycan core protein deduced from cDNA clones.
K Doege;M Sasaki;E Horigan;J R Hassell.
Journal of Biological Chemistry (1987)
The presence of heparan sulfate proteoglycans in the neuritic plaques and congophilic angiopathy in Alzheimer's disease.
A. D. Snow;H. Mar;D. Nochlin;K. Kimata.
American Journal of Pathology (1988)
The molecular basis of corneal transparency
John R. Hassell;David E. Birk.
Experimental Eye Research (2010)
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