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Biology and Biochemistry

D-Index
61
Citations
10037
World Ranking
11603
National Ranking
4994

Overview

James L. Funderburgh was affiliated with the University of Pittsburgh in the United States. Their research focused primarily on the field of Medicine, with significant contributions in Radiology, Nuclear Medicine and Imaging, Public Health, Environmental and Occupational Health, Surgery, Molecular Biology, and Cancer Research.

The scientist's main topics of work included:

  • Corneal Surgery and Treatments
  • Corneal surgery and disorders
  • Ocular Surface and Contact Lens
  • Tissue Engineering and Regenerative Medicine
  • Extracellular vesicles in disease
  • MicroRNA in disease regulation
  • Mesenchymal stem cell research

Throughout their career, James L. Funderburgh published in various journals such as:

  • Journal of Advanced Research
  • Eye and Vision
  • Experimental Eye Research
  • International Journal of Molecular Sciences
  • Communications Materials

Among their recent papers were:

  • "Human corneal stromal stem cells express anti-fibrotic microRNA-29a and 381-5p - A robust cell selection tool for stem cell therapy of corneal scarring", 2022, Journal of Advanced Research
  • "The anti-scarring effect of corneal stromal stem cell therapy is mediated by transforming growth factor β3", 2020, Eye and Vision
  • "A novel transgenic mouse model for corneal scar visualization", 2020, Experimental Eye Research
  • "Generation of Functional Immortalized Human Corneal Stromal Stem Cells", 2022, International Journal of Molecular Sciences
  • "In vivo engraftment into the cornea endothelium using extracellular matrix shrink-wrapped cells", 2022, Communications Materials

Funderburgh collaborated frequently with other researchers, including:

  • Moira L. Geary
  • Yiqin Du
  • Martha L. Funderburgh
  • Irona Khandaker
  • Gary Hin-Fai Yam

Their work addressed various aspects of corneal biology and regenerative medicine, investigating mechanisms such as microRNA regulation and stem cell therapies aimed at treating corneal scarring and disorders. This focus extended into developing models for visualization of corneal scars and enhancing understanding of extracellular matrix interactions in corneal cells.

Best Publications

  • MINI REVIEW Keratan sulfate: structure, biosynthesis, and function

    James L. Funderburgh

  • Multipotent stem cells in human corneal stroma.

    Yiqin Du;Martha L. Funderburgh;Mary M. Mann;Nirmala SundarRaj

  • Role of Lumican in the Corneal Epithelium during Wound Healing

    Shizuya Saika;Atsushi Shiraishi;Satoko Saika;Chia-Yang Liu

  • Keratocyte Phenotype Mediates Proteoglycan Structure A ROLE FOR FIBROBLASTS IN CORNEAL FIBROSIS

    James L. Funderburgh;Mary M. Mann;Martha L. Funderburgh

  • Proteoglycan synthesis by bovine keratocytes and corneal fibroblasts: maintenance of the keratocyte phenotype in culture.

    Marianne P. Beales;James L. Funderburgh;James V. Jester;John R. Hassell;John R. Hassell

  • Stem Cell Therapy Restores Transparency to Defective Murine Corneas

    Yiqin Du;Eric C. Carlson;Martha L. Funderburgh;David E. Birk

  • Molecular Cloning and Tissue Distribution of Keratocan BOVINE CORNEAL KERATAN SULFATE PROTEOGLYCAN 37A

    Lolita M. Corpuz;James L. Funderburgh;Martha L. Funderburgh;George S. Bottomley

  • Human limbal biopsy–derived stromal stem cells prevent corneal scarring

    Sayan Basu;Andrew J. Hertsenberg;Martha L. Funderburgh;Michael K. Burrow

  • Mimecan, the 25-kDa Corneal Keratan Sulfate Proteoglycan, Is a Product of the Gene Producing Osteoglycin

    James L. Funderburgh;Lolita M. Corpuz;Mary R. Roth;Martha L. Funderburgh

  • Concise Review: Stem Cells in the Corneal Stroma

    Niveditha Pinnamaneni;James L. Funderburgh

  • Proteoglycan Expression during Transforming Growth Factor β-induced Keratocyte-Myofibroblast Transdifferentiation

    James L. Funderburgh;Martha L. Funderburgh;Mary M. Mann;Lolita M. Corpuz

  • Keratan sulfate biosynthesis.

    James L. Funderburgh

  • Regenerating Eye Tissues to Preserve and Restore Vision.

    Jeffrey H. Stern;Yangzi Tian;James Funderburgh;Graziella Pellegrini

  • Keratocan, a Cornea-specific Keratan Sulfate Proteoglycan, Is Regulated by Lumican

    Eric C. Carlson;Chia-Yang Liu;Tai-ichiro Chikama;Yasuhito Hayashi

  • Mesenchymal Stem Cells Reduce Corneal Fibrosis and Inflammation via Extracellular Vesicle-Mediated Delivery of miRNA

    Golnar Shojaati;Golnar Shojaati;Irona Khandaker;Martha L. Funderburgh;Mary M. Mann

  • Characterization and Expression of the Mouse Lumican Gene

    Saixia Ying;Atsushi Shiraishi;Candace W.-C. Kao;Richard L. Converse

  • The engineering of organized human corneal tissue through the spatial guidance of corneal stromal stem cells

    Jian Wu;Yiqin Du;Simon C. Watkins;James L. Funderburgh

  • Adipose-derived stem cells differentiate to keratocytes in vitro.

    Du Y;Roh Ds;Funderburgh Ml;Mann Mm

  • Functional reconstruction of rabbit corneal epithelium by human limbal cells cultured on amniotic membrane.

    Yiqin Du;Jing Chen;James L Funderburgh;Xiuan Zhu

  • Limbal Biopsy Derived Stromal Stem Cells Prevent Corneal Scarring

    Sayan Basu;Sayan Basu;Andrew Hertsenberg;Martha L Funderburgh;James L Funderburgh

Frequent Co-Authors

Chia-Yang Liu
Chia-Yang Liu Indiana University
David L. Kaplan
David L. Kaplan Tufts University
Winston W.-Y. Kao
Winston W.-Y. Kao University of Cincinnati
David E. Birk
David E. Birk University of South Florida
William R. Wagner
William R. Wagner University of Pittsburgh
Joel S. Schuman
Joel S. Schuman Wills Eye Hospital
John R. Hassell
John R. Hassell University of South Florida
Robin R. Ali
Robin R. Ali King's College London
David Ayares
David Ayares University of Maryland, Baltimore
Simon C. Watkins
Simon C. Watkins University of Pittsburgh

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