World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
140
Citations
76097
World Ranking
272
National Ranking
186

Overview

Renato V. Iozzo is affiliated with Thomas Jefferson University in the United States and has a research focus predominantly in the fields of Biochemistry, Genetics and Molecular Biology, as well as Medicine. Their scholarly output includes 95 publications related to biochemistry and molecular biology topics and 57 publications within medical research.

Their research spans several subfields, notably Cell Biology with 42 published works, Molecular Biology with 38, Epidemiology with 9, Immunology and Allergy with 8, and Cancer Research with 7. The main topics covered in their work include proteoglycans and glycosaminoglycans research, with 66 publications addressing this area. Other frequently investigated themes are glycosylation and glycoproteins research (16 publications), fibroblast growth factor research (16), cell adhesion molecules research (16), angiogenesis and VEGF in cancer (16), autophagy in disease and therapy (14), and connective tissue disorders research (12).

Renato V. Iozzo has authored several recent papers that contribute to the understanding of extracellular matrix components and their roles in disease, including:

  • The Role of Decorin and Biglycan Signaling in Tumorigenesis, 2021, Frontiers in Oncology
  • Decorin deficiency promotes epithelial-mesenchymal transition and colon cancer metastasis, 2020, Matrix Biology
  • Mediation of Cartilage Matrix Degeneration and Fibrillation by Decorin in Post-traumatic Osteoarthritis, 2020, Arthritis & Rheumatology
  • Decorin regulates cartilage pericellular matrix micromechanobiology, 2020, Matrix Biology
  • Oncosuppressive roles of decorin through regulation of multiple receptors and diverse signaling pathways, 2022, American Journal of Physiology-Cell Physiology

Their publications are frequently found in specialized scientific journals with a focus on extracellular matrix biology and molecular biochemistry. Key publication venues include:

  • Matrix Biology (13 publications)
  • Matrix Biology Plus (5 publications)
  • Journal of Biological Chemistry (5 publications)
  • Proteoglycan Research (5 publications)
  • American Journal of Physiology-Cell Physiology (3 publications)

Renato V. Iozzo collaborates regularly with a core group of coauthors who have contributed to multiple scientific outputs. These include Simone Buraschi (17 publications), Christopher Xie (10 publications), Thomas Neill (10 publications), Antonino Belfiore (9 publications), and Andrea Morrione (9 publications).

Best Publications

  • Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

    Daniel J. Klionsky;Amal Kamal Abdel-Aziz;Sara Abdelfatah;Mahmoud Abdellatif

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • Matrix Proteoglycans: From Molecular Design to Cellular Function

    Renato V. Iozzo

  • Targeted Disruption of Decorin Leads to Abnormal Collagen Fibril Morphology and Skin Fragility

    Keith G. Danielson;Helene Baribault;David F. Holmes;Helen Graham

  • Proteoglycan form and function: A comprehensive nomenclature of proteoglycans

    Renato V. Iozzo;Liliana Schaefer

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • Proteoglycans of the extracellular environment: clues from the gene and protein side offer novel perspectives in molecular diversity and function.

    Renato V. Iozzo;Alan D. Murdoch

  • The biology of the small leucine-rich proteoglycans. Functional network of interactive proteins.

    Renato V. Iozzo

  • The Degradation of Human Endothelial Cell-derived Perlecan and Release of Bound Basic Fibroblast Growth Factor by Stromelysin, Collagenase, Plasmin, and Heparanases

    John M. Whitelock;Alan D. Murdoch;Renato V. Iozzo;P. Anne Underwood

  • Fibroblast growth factor-2.

    Matthew A Nugent;Renato V Iozzo

  • Proteoglycans in cancer biology, tumour microenvironment and angiogenesis

    Renato V. Iozzo;Ralph D. Sanderson

  • Basement membrane proteoglycans: from cellar to ceiling.

    Renato V. Iozzo

  • The family of the small leucine-rich proteoglycans: key regulators of matrix assembly and cellular growth.

    Renato V. Iozzo

  • Phenotypic effects of biglycan deficiency are linked to collagen fibril abnormalities, are synergized by decorin deficiency, and mimic Ehlers-Danlos-like changes in bone and other connective tissues.

    A. Corsi;T. Xu;Xiao-dong Chen;A. Boyde

  • Biological functions of the small leucine-rich proteoglycans: from genetics to signal transduction.

    Liliana Schaefer;Renato V. Iozzo

  • Heparan sulfate proteoglycans: heavy hitters in the angiogenesis arena.

    Renato V. Iozzo;James D. San Antonio

  • Heparan sulfate: a complex polymer charged with biological activity.

    John M. Whitelock;Renato V. Iozzo

  • The role of decorin in collagen fibrillogenesis and skin homeostasis

    Charles C. Reed;Renato V. Iozzo

  • Mice that lack thrombospondin 2 display connective tissue abnormalities that are associated with disordered collagen fibrillogenesis, an increased vascular density, and a bleeding diathesis.

    Themis R. Kyriakides;Yu Hong Zhu;Lynne T. Smith;Steven D. Bain

  • Biological Functions of the Small Leucine-rich Proteoglycans: From Genetics to

    Liliana Schaefer;Renato V. Iozzo

Frequent Co-Authors

Liliana Schaefer
Liliana Schaefer Goethe University Frankfurt
Leonard G. Gomella
Leonard G. Gomella Thomas Jefferson University
John M. Whitelock
John M. Whitelock University of New South Wales
David E. Birk
David E. Birk University of South Florida
Bruno Calabretta
Bruno Calabretta Thomas Jefferson University
Louis J. Soslowsky
Louis J. Soslowsky University of Pennsylvania
Stephen C. Peiper
Stephen C. Peiper Thomas Jefferson University
Marian F. Young
Marian F. Young National Institutes of Health
Nikos K. Karamanos
Nikos K. Karamanos University of Patras
Matteo Fassan
Matteo Fassan University of Padua

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