What is he best known for?
The fields of study he is best known for:
His primary scientific interests are in Molecular biology, Cancer research, Cell growth, Cell biology and Cell culture.
Bruno Calabretta has researched Molecular biology in several fields, including Haematopoiesis and Complementary DNA, MYB, Gene expression, Gene.
The Cancer research study combines topics in areas such as Apoptosis, ABL, Chronic myelogenous leukemia, Leukemia and breakpoint cluster region.
His biological study spans a wide range of topics, including Protein biosynthesis, K562 cells, Philadelphia chromosome and Untranslated region.
His research integrates issues of Phenotype, Cell cycle and In vitro in his study of Cell growth.
His Cell biology research incorporates themes from Cyclin B, Cyclin A and Cyclin D.
His most cited work include:
- Guidelines for the use and interpretation of assays for monitoring autophagy (3242 citations)
- Transformation of hematopoietic cells by BCR/ABL requires activation of a PI-3k/Akt-dependent pathway (550 citations)
- THE BIOLOGY OF CML BLAST CRISIS (485 citations)
What are the main themes of his work throughout his whole career to date?
Molecular biology, Cancer research, Cell biology, Haematopoiesis and Cell culture are his primary areas of study.
His Molecular biology research is multidisciplinary, incorporating perspectives in Gene expression, Cellular differentiation, Messenger RNA, Gene and MYB.
His Cancer research study combines topics from a wide range of disciplines, such as ABL, Chronic myelogenous leukemia, Leukemia, Stem cell and breakpoint cluster region.
His study in breakpoint cluster region is interdisciplinary in nature, drawing from both Tyrosine kinase and Philadelphia chromosome.
The concepts of his Cell biology study are interwoven with issues in Cell cycle, Apoptosis and Transfection.
His Cell culture research is multidisciplinary, relying on both Cell growth and Sense.
He most often published in these fields:
- Molecular biology (45.17%)
- Cancer research (48.29%)
- Cell biology (23.36%)
What were the highlights of his more recent work (between 2008-2021)?
- Cancer research (48.29%)
- Stem cell (10.90%)
- Transcription factor (9.97%)
In recent papers he was focusing on the following fields of study:
Bruno Calabretta spends much of his time researching Cancer research, Stem cell, Transcription factor, Cell biology and Leukemia.
Bruno Calabretta does research in Cancer research, focusing on Myeloid leukemia specifically.
His Stem cell research includes elements of Autophagy, Chronic myelogenous leukemia and Imatinib mesylate.
His Cell biology research incorporates elements of Cell culture and K562 cells.
His work in K562 cells addresses issues such as Ccaat-enhancer-binding proteins, which are connected to fields such as Molecular biology and Enhancer binding.
His Molecular biology study incorporates themes from Transfection and Phosphorylation.
Between 2008 and 2021, his most popular works were:
- Guidelines for the use and interpretation of assays for monitoring autophagy (3242 citations)
- Targeting autophagy potentiates tyrosine kinase inhibitor-induced cell death in Philadelphia chromosome-positive cells, including primary CML stem cells. (459 citations)
- Inhibiting Interactions of Lysine Demethylase LSD1 with Snail/Slug Blocks Cancer Cell Invasion (90 citations)
In his most recent research, the most cited papers focused on:
Bruno Calabretta mainly focuses on Cancer research, Stem cell, Myeloid leukemia, Molecular biology and Cancer cell.
Bruno Calabretta mostly deals with Imatinib mesylate in his studies of Cancer research.
His work carried out in the field of Stem cell brings together such families of science as Autophagy, Chronic myelogenous leukemia, Cellular differentiation and ABL.
His Molecular biology study combines topics in areas such as MYB, Protein stabilization and Cell biology.
He works mostly in the field of Cell biology, limiting it down to topics relating to K562 cells and, in certain cases, CD34 and Haematopoiesis.
His Cancer cell research focuses on Cancer stem cell and how it relates to breakpoint cluster region.
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